Transcription factor AP-2-delta (Protein name
), AP2D_MOUSE from NCBI database.
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Gene name:
Tcfap2d(Tcfap2d);
Protein name:
Transcription factor AP-2-delta(AP2-delta);
Alternative:
Activating enhancer-binding protein 2-delta;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members.
Function:
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
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Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBUNIT;TISSUE SPECIFICITY