Gene name:
AP3B1 (ADTB3A) ;
Protein name:
AP-3 complex subunit beta-1 ;
Alternative:
Adaptor protein complex AP-3 subunit beta-1 ;Adapter-related protein complex 3 subunit beta-1 ;Clathrin assembly protein complex 3 beta-1 large chain ;Beta-3A-adaptin ;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Sub Unit:
Adaptor protein complex 3 (AP-3) is an heterotetramer composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin (mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2).
Function:
Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles.
Subcellular Location:
Golgi apparatus
Cytoplasmic vesicle
clathrin-coated vesicle membrane
Peripheral membrane protein
Cytoplasmic side
Golgi apparatus
Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein Attributes:
50:
MSGNSFAYSE | QAGGGEATEL | GQEATSTVSP | SGAFGLFSSD | LKKNEDLKQM |
100:
LESNKDSAKL | DAMKRIVGMI | AKGKNASELF | PAVVKNVASK | NIEIKKLVYV |
150:
YLVRYAEEQQ | DLALLSISTF | QRALKDPNQL | IRASALRVLS | SIRVPIIVPI |
200:
MMLAIKEASA | DLSPYVRKNA | AHAIQKLYSL | DPEQKEMLIE | VIEKLLKDKS |
250:
TLVAGSVVMA | FEEVCPDRID | LIHKNYRKLC | NLLVDVEEWG | QVVIIHMLTR |
300:
YARTQFVSPW | KEDDGLEDNE | KNFYESDDEQ | KEKTDQKKKP | YAMDPDHRLL |
350:
IRNTKPLLQS | RNAAVVMAVA | QLYWHISPKS | EVGIISKSLV | RLLRSNREVQ |
400:
YIVLQNIATM | SIQRKGMLEP | YLKSFYVRST | DPTMIKILKL | EILTNLANEA |
450:
NISTLLREFQ | TYVKSQDKQF | AAATIQTIGR | CATSISEVTD | TCLSGLVCLL |
500:
SNRDEIVVAE | SVVVIKKLLQ | MQPAQHGEII | KHMAKLLDSI | TVPVARASIL |
550:
WLIGENCERV | PKIAPDVLRK | MAKSFTNEDD | LVKLQILNLG | AKLYLTNSKQ |
600:
TKLLTQYILN | LGKYDQNYDI | RDRTRFIRQL | IVPNEKSGAL | SKYAKKIFLA |
650:
QKPAPLLESP | FKDRDHFQLG | TLSHTLNTKA | IGYLELSNWP | EVAPDPSVRN |
700:
VEVIELQAKE | WTPAGKAKKE | NPARKFYSDS | EEEEDSSDSS | SDSESESGSA |
750:
SGEQDEEGDS | SEDSSEDSSS | EHRSDSESVS | EVGDKRTAKR | NSKSKGKSDS |
800:
EDEEKENEKS | KTSDSSSTDS | SSVEESSSDS | ESESESESES | ESKKVTMEKE |
850:
KKTKEDRNLT | KDVSLLDLDD | FNPVSTPVVL | PTPALSPSLI | ADLEGLNLST |
900:
SSSVISVNTP | VFVPVKTHVL | LHRMSGRGLA | AHYFFPRQPC | IFGDKMVSIQ |
950:
ITLNNTTDRK | IENIHIEGKK | LPMGMQMHVF | NPIESLEPEG | SITVSMGIDF |
1000:
CDSTQTASFQ | LCTKDDCFNV | NIQPPVGELL | LPVAMSEKDF | KKEQGMLTGM |
1050:
NETSTVIIAA | PQNFTPSVIL | QKVVNIANVG | VVPSGQDNIY | RFAAKTVHSG |
1091:
SLMLVTVELK | EGSTAQLIIN | TERTVIGSVL | LRELKPVLSQ | G
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Bovine
Human
Dog
ELISA Kit for Dog AP-3 complex subunit beta-1
ELISA Kit for Dog AP-3 complex subunit beta-1
ELISA Kit for Dog AP-3 complex subunit beta-1
ELISA Kit for Dog AP-3 complex subunit beta-1
CLIA Kit for Dog AP-3 complex subunit beta-1
CLIA Kit for Dog AP-3 complex subunit beta-1
CLIA Kit for Dog AP-3 complex subunit beta-1
CLIA Kit for Dog AP-3 complex subunit beta-1
Polyclonal Antibody for Dog AP-3 complex subunit beta-1
Polyclonal Antibody for Dog AP-3 complex subunit beta-1
Polyclonal Antibody for Dog AP-3 complex subunit beta-1
Polyclonal Antibody for Dog AP-3 complex subunit beta-1
Monoclonal Antibody for Dog AP-3 complex subunit beta-1
Monoclonal Antibody for Dog AP-3 complex subunit beta-1
Monoclonal Antibody for Dog AP-3 complex subunit beta-1
Monoclonal Antibody for Dog AP-3 complex subunit beta-1
Protein for Dog AP-3 complex subunit beta-1
Protein for Dog AP-3 complex subunit beta-1
Protein for Dog AP-3 complex subunit beta-1
Protein for Dog AP-3 complex subunit beta-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
Benson K.F.
,
Li F.-Q.
,
Person R.E.
,
Albani D.
,
Duan Z.
,
Wechsler J.
,
Meade-White K.
,
Williams K.
,
Acland G.M.
,
Niemeyer G.
,
Lothrop C.D.
,
Horwitz M.
Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Peripheral blood .