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Index > Protein center > Ap3b2(Gene name) > Mouse
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  • Ap3b2 (Gene name),
  • AP-3 complex subunit beta-2 (Protein name ),  AP3B2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ap3b2;
    Protein name:
    AP-3 complex subunit beta-2;
    Alternative:
    Adaptor protein complex AP-3 subunit beta-2;Adapter-related protein complex 3 subunit beta-2;Clathrin assembly protein complex 3 beta-2 large chain;Beta-3B-adaptin;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Adaptor protein complex 3 (AP-3) is an heterotetramer composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin (mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2).
    Function:
    Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles.
    Subcellular Location:
    Golgi apparatus Cytoplasmic vesicle clathrin-coated vesicle membrane Peripheral membrane protein Cytoplasmic side Golgi apparatus Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
    Protein Attributes:
    Sequence length:
    1082
    Sequence:
    50:
    MSAAPAYSED | KGGSAGPGEP | EYGHDPASGG | IFSSDYKRHD | DLKEMLDTNK | 
    100:
    DSLKLEAMKR | IVAMIARGKN | ASDLFPAVVK | NVACKNIEVK | KLVYVYLVRY | 
    150:
    AEEQQDLALL | SISTFQRGLK | DPNQLIRASA | LRVLSSIRVP | IIVPIMMLAI | 
    200:
    KEAASDMSPY | VRKTAAHAIP | KLYSLDSDQK | DQLIEVIEKL | LADKTTLVAG | 
    250:
    SVVMAFEEVC | PERIDLIHKN | YRKLCNLLID | VEEWGQVVII | SMLTRYARTQ | 
    300:
    FLSPTQNESL | LEENPEKAFY | GSEEDEAKGP | GSEEAATAAL | PARKPYVMDP | 
    350:
    DHRLLLRNTK | PLLQSRSAAV | VMAVAQLYFH | LAPKAEVGVI | AKALVRLLRS | 
    400:
    HSEVQYVVLQ | NVATMSIKRR | GMFEPYLKSF | YIRSTDPTQI | KILKLEVLTN | 
    450:
    LANETNIPTV | LREFQTYIRS | MDKDFVAATI | QAIGRCATNI | GRVRDTCLNG | 
    500:
    LVQLLSNRDE | LVVAESVVVI | KKLLQMQPAQ | HGEIIKHLAK | LTDNIQVPMA | 
    550:
    RASILWLIGE | YCEHVPKIAP | DVLRKMAKSF | TAEEDIVKLQ | VINLAAKLYL | 
    600:
    TNSKQTKLLT | QYVLSLAKYD | QNYDIRDRAR | FTRQLIVPSE | QGGALSRHAK | 
    650:
    KLFLAPKPAP | ILESSFKDRD | HFQLGSLSHL | LNAKATGYQE | LPDWPEEAPD | 
    700:
    PSVRNVEVPE | WTKCSNREKR | KEKEKPFYSD | SEGESGPTES | ADSEPESESE | 
    750:
    SESKSSSGSG | SGESSSESDN | EEEDEEKGGG | SESEQSEEED | EKKKKTKKKK | 
    800:
    ASEGHREGSS | SEEGSDSSSS | SESEVTSESE | EEQVEPASWR | KKTPPGSKSA | 
    850:
    PVAKEISLLD | LEDFTPPSVQ | PVSPPMVVST | SLAADLEGLT | LTDSSLVPSL | 
    900:
    LSPVSSIGRQ | ELLHRVAGEG | LSVDYAFSRQ | PFSGDPHMVS | LHIYFSNNSE | 
    950:
    TPIKGLHVGT | PKLPAGISIQ | EFPEIESLAP | GESTTTVMGI | NFCDSTQAAN | 
    1000:
    FQLCTQTRQF | YVSIQPPVGE | LMAPVFMSEN | EFKKEQGKLT | GMNEITEKLT | 
    1050:
    LPDTCRSDHM | VVQKVTATAN | LGRVPCGTSD | EYRFAGRTLT | SGSLVLLTLD | 
    1082:
    ARAAGAAQLT | VNSEKMVIGT | MLVKDVIQAL | TQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse AP-3 complex subunit beta-2
    ELISA Kit for Mouse AP-3 complex subunit beta-2
    CLIA Kit for Mouse AP-3 complex subunit beta-2
    CLIA Kit for Mouse AP-3 complex subunit beta-2
    Polyclonal Antibody for Mouse AP-3 complex subunit beta-2
    Polyclonal Antibody for Mouse AP-3 complex subunit beta-2
    Monoclonal Antibody for Mouse AP-3 complex subunit beta-2
    Monoclonal Antibody for Mouse AP-3 complex subunit beta-2
    Protein for Mouse AP-3 complex subunit beta-2
    Protein for Mouse AP-3 complex subunit beta-2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Ap3b2, a neuron specific subunit of adaptor protein complex 3 (AP-3)."
      Seong E. , Burmeister M.
      Submitted (2004-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6J.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-738
      strain: C57BL/6J.
      tissue: Embryonic head.
    4. 4.
      "Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains."
      Inoue S. , Sano H. , Ohta M.
      Biochem. Biophys. Res. Commun.268:553-561(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 608-1082
      tissue: Brain.
    5. 5.
      "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
      Munton R.P. , Tweedie-Cullen R. , Livingstone-Zatchej M. , Weinandy F. , Waidelich M. , Longo D. , Gehrig P. , Potthast F. , Rutishauser D. , Gerrits B. , Panse C. , Schlapbach R. , Mansuy I.M.
      Mol. Cell. Proteomics6:283-293(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain cortex.
    6. 6.
      "The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse."
      Larimore J. , Tornieri K. , Ryder P.V. , Gokhale A. , Zlatic S.A. , Craige B. , Lee J.D. , Talbot K. , Pare J.F. , Smith Y. , Faundez V.
      Mol. Biol. Cell22:4854-4867(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ASSOCIATION WITH THE BLOC-1 COMPLEX
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