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Index > Protein center > APBA3(Gene name) > Human
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  • APBA3 (Gene name),
  • Amyloid beta A4 precursor protein-binding family A member 3 (Protein name ),  APBA3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    APBA3(MINT3;X11L2);
    Protein name:
    Amyloid beta A4 precursor protein-binding family A member 3;
    Alternative:
    Neuron-specific X11L2 protein;Adapter protein X11gamma;Neuronal Munc18-1-interacting protein 3(Mint-3);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds to the cytoplasmic domain of amyloid protein (APP) in vivo.
    Function:
    May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    575
    Sequence:
    50:
    MDFPTISRSP | SGPPAMDLEG | PRDILVPSED | LTPDSQWDPM | PGGPGSLSRM | 
    100:
    ELDESSLQEL | VQQFEALPGD | LVGPSPGGAP | CPLHIATGHG | LASQEIADAH | 
    150:
    GLLSAEAGRD | DLLGLLHCEE | CPPSQTGPEE | PLEPAPRLLQ | PPEDPDEDSD | 
    200:
    SPEWVEGASA | EQEGSRSSSS | SPEPWLETVP | LVTPEEPPAG | AQSPETLASY | 
    250:
    PAPQEVPGPC | DHEDLLDGVI | FGARYLGSTQ | LVSERNPPTS | TRMAQAREAM | 
    300:
    DRVKAPDGET | QPMTEVDLFV | STKRIKVLTA | DSQEAMMDHA | LHTISYTADI | 
    350:
    GCVLVLMARR | RLARRPAPQD | HGRRLYKMLC | HVFYAEDAQL | IAQAIGQAFA | 
    400:
    AAYSQFLRES | GIDPSQVGVH | PSPGACHLHN | GDLDHFSNSD | NCREVHLEKR | 
    450:
    RGEGLGVALV | ESGWGSLLPT | AVIANLLHGG | PAERSGALSI | GDRLTAINGT | 
    500:
    SLVGLPLAAC | QAAVRETKSQ | TSVTLSIVHC | PPVTTAIIHR | PHAREQLGFC | 
    550:
    VEDGIICSLL | RGGIAERGGI | RVGHRIIEIN | GQSVVATPHA | RIIELLTEAY | 
    575:
    GEVHIKTMPA | ATYRLLTGQE | QPVYL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    MIM:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Amyloid beta A4 precursor protein-binding family A member 3
    ELISA Kit for Human Amyloid beta A4 precursor protein-binding family A member 3
    ELISA Kit for Human Amyloid beta A4 precursor protein-binding family A member 3
    CLIA Kit for Human Amyloid beta A4 precursor protein-binding family A member 3
    CLIA Kit for Human Amyloid beta A4 precursor protein-binding family A member 3
    CLIA Kit for Human Amyloid beta A4 precursor protein-binding family A member 3
    Polyclonal Antibody for Human Amyloid beta A4 precursor protein-binding family A member 3
    Polyclonal Antibody for Human Amyloid beta A4 precursor protein-binding family A member 3
    Polyclonal Antibody for Human Amyloid beta A4 precursor protein-binding family A member 3
    Monoclonal Antibody for Human Amyloid beta A4 precursor protein-binding family A member 3
    Monoclonal Antibody for Human Amyloid beta A4 precursor protein-binding family A member 3
    Monoclonal Antibody for Human Amyloid beta A4 precursor protein-binding family A member 3
    Protein for Human Amyloid beta A4 precursor protein-binding family A member 3
    Protein for Human Amyloid beta A4 precursor protein-binding family A member 3
    Protein for Human Amyloid beta A4 precursor protein-binding family A member 3

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "X11L2, a new member of X11 protein family interacts with Alzheimer's beta-amyloid precursor protein."
      Tanahashi H. , Tabira T.
      Biochem. Biophys. Res. Commun.255:663-667(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    4. 4.
      "Genomic organization of the human X11L2 gene (APBA3), a third member of the X11 protein family interacting with Alzheimer's beta-amyloid precursor protein."
      Tanahashi H. , Tabira T.
      NeuroReport10:2575-2578(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 207-575
    5. 5.
      "Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2."
      Okamoto M. , Suedhof T.C.
      Eur. J. Cell Biol.77:161-165(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 472-575
    6. 6.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-372;VARIANT [LARGE SCALE ANALYSIS] ARG-376;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "Mint3 enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1."
      Sakamoto T. , Seiki M.
      J. Biol. Chem.284:30350-30359(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH HIF1AN;SUBCELLULAR LOCATION
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Solution structure of the PDZ domain of amyloid beta A4 precursor protein-binding family A member 3."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2008-04) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 387-569
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