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Index > Protein center > ANAPC13(Gene name) > Human
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  • ANAPC13 (Gene name),
  • Anaphase-promoting complex subunit 13 (Protein name ),  APC13_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    ANAPC13;
    Protein name:
    Anaphase-promoting complex subunit 13(APC13);
    Alternative:
    Cylosome subunit 13;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    The APC/C is composed of at least 12 subunits.
    Function:
    Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    74
    Sequence:
    50:
    MDSEVQRDGR | ILDLIDDAWR | EDKLPYEDVA | IPLNELPEPE | QDNGGTTESV | 
    74:
    KEQEMKWTDL | ALQYLHENVP | PIGN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    MIM:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human APC13
    ELISA Kit for Human APC13
    ELISA Kit for Human APC13
    CLIA Kit for Human APC13
    CLIA Kit for Human APC13
    CLIA Kit for Human APC13
    Polyclonal Antibody for Human APC13
    Polyclonal Antibody for Human APC13
    Polyclonal Antibody for Human APC13
    Monoclonal Antibody for Human APC13
    Monoclonal Antibody for Human APC13
    Monoclonal Antibody for Human APC13
    Protein for Human APC13
    Protein for Human APC13
    Protein for Human APC13

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    3. 3.
      "Swm1/Apc13 is an evolutionarily conserved subunit of the anaphase-promoting complex stabilizing the association of Cdc16 and Cdc27."
      Schwickart M. , Havlis J. , Habermann B. , Bogdanova A. , Camasses A. , Oelschlaegel T. , Shevchenko A. , Zachariae W.
      Mol. Cell. Biol.24:3562-3576(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    4. 4.
      "Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C."
      Dube P. , Herzog F. , Gieffers C. , Sander B. , Riedel D. , Mueller S.A. , Engel A. , Peters J.-M. , Stark H.
      Mol. Cell20:867-879(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE APC/C COMPLEX
    5. 5.
      "Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex."
      Jin L. , Williamson A. , Banerjee S. , Philipp I. , Rape M.
      Cell133:653-665(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF THE APC/C
    6. 6.
      "Molecular architecture and mechanism of the anaphase-promoting complex."
      Chang L. , Zhang Z. , Yang J. , McLaughlin S.H. , Barford D.
      Nature513:388-393(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY ELECTRON MICROSCOPY (7.4 ANGSTROMS) OF THE APC/C;SUBUNIT
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