Protein name:
Anaphase-promoting complex subunit 5 (APC5) ;
Alternative:
Cyclosome subunit 5 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
The APC/C is composed of at least 12 subunits.
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Subcellular Location:
N/A
Protein Attributes:
50:
MASVHESLYF | NPMMTNGVVH | ANVFGIKDWV | TPYKIAVLVL | LNEMSRTGEG |
100:
AVSLMERRRL | NQLLLPLLQG | PDITLSKLYK | LIEESCPQLA | NSVQIRIKLM |
150:
AEGELKDMEQ | FFDDLSDSFS | GTEPEVHKTS | VVGLFLRHMI | LAYSKLSFSQ |
200:
VFKLYTALQQ | YFQNGEKKTV | EDADMELTSR | DEGERKMEKE | ELDVSVREEE |
250:
VSCSGPLSQK | QAEFFLSQQA | SLLKNDETKA | LTPASLQKEL | NNLLKFNPDF |
300:
AEAHYLSYLN | NLRVQDVFSS | THSLLHYFDR | LILTGAESKS | NGEEGYGRSL |
350:
RYAALNLAAL | HCRFGHYQQA | ELALQEAIRI | AQESNDHVCL | QHCLSWLYVL |
400:
GQKRSDSYVL | LEHSVKKAVH | FGLPYLASLG | IQSLVQQRAF | AGKTANKLMD |
450:
ALKDSDLLHW | KHSLSELIDI | SIAQKTAIWR | LYGRSTMALQ | QAQMLLSMNS |
500:
LEAVNAGVQQ | NNTESFAVAL | CHLAELHAEQ | GCFAAASEVL | KHLKERFPPN |
550:
SQHAQLWMLC | DQKIQFDRAM | NDGKYHLADS | LVTGITALNS | IEGVYRKAVV |
600:
LQAQNQMSEA | HKLLQKLLVH | CQKLKNTEMV | ISVLLSVAEL | YWRSSSPTIA |
650:
LPMLLQALAL | SKEYRLQYLA | SETVLNLAFA | QLILGIPEQA | LSLLHMAIEP |
700:
ILADGAILDK | GRAMFLVAKC | QVASAASYDQ | PKKAEALEAA | IENLNEAKNY |
750:
FAKVDCKERI | RDVVYFQARL | YHTLGKTQER | NRCAMLFRQL | HQELPSHGVP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Chicken
Human
Rat
Polyclonal Antibody for Human APC5
Polyclonal Antibody for Human APC5
Polyclonal Antibody for Human APC5
Polyclonal Antibody for Human APC5
Monoclonal Antibody for Human APC5
Monoclonal Antibody for Human APC5
Monoclonal Antibody for Human APC5
Monoclonal Antibody for Human APC5
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Esophagus .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Brain .
tissue :
Cervix .
tissue :
Lung .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT SER-195
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION OF THE APC/C
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TPR REPEATS
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ELECTRON MICROSCOPY OF THE APC/C
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY ELECTRON MICROSCOPY (7.4 ANGSTROMS) OF THE APC/C;SUBUNIT
13.
"The consensus coding sequences of human breast and colorectal cancers."
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Science314:268-274(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : VARIANT [LARGE SCALE ANALYSIS] HIS-617