Protein name:
Putative gamma-secretase subunit APH-1C;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Potential component of the gamma-secretase complex.
Function:
Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein).
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MTLPVFFGCA | FIAFGPAFAL | YLFTIATDPL | RVIFLIAGAF | FWLVSLLLSS |
100:
MFWFLVRVIT | NNRDESVQNY | LLIFGALLSV | CIQELFRLAY | YKLLKKASEG |
150:
LKSINPEEDI | APSMRLLAYV | SGLGFGIMSG | VFSFVNTLSN | SLGPGTVGIH |
200:
GDSPQFFLNS | AFMTLVVIML | HVFWGVVFFD | GCEKNKWYTL | LTVLLTHLVV |
250:
STQTFLSPYY | EVNLVTAYII | MVLMGIWAFY | VAGGSCRSLK | FCLLCQDKDF |

Vaild Sequence:
Related Databases
Uniprot: