Aplp1 ELISA Kit for Mouse(Mus musculus) | EIAab.comAplp1 ELISA Kit for Mouse(Mus musculus)

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Aplp1 (Gene name),

Amyloid-like protein 1 (Protein name ), APLP1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Aplp1;

Protein name:

Amyloid-like protein 1(APLP;APLP-1);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Monomer and homodimer. Heparin binding promotes homodimerization. Binds, via its C-terminus, to the PID domain of several cytoplasmic proteins, including APBB and APBA family members, MAPK8IP1 and Dab1 (By similarity). Binding to Dab1 inhibits its serine phosphorylation. Interacts with CPEB1.

Function:

The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.

Subcellular Location:

C30 Cytoplasm C-terminally processed in the Golgi complex.

Protein Attributes:

Sequence length:

653

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

653:

ERP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.2381

Pfam:

PF10515

KEGG:

mmu:11803

String:

Q03157

SMR:

Q03157

Uniprot:

Q03157

FOR

ELISA Kit for Mouse APLP

CLIA Kit for Mouse APLP

Polyclonal Antibody for Mouse APLP

Monoclonal Antibody for Mouse APLP

Protein for Mouse APLP

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor."
Wasco W. , Bupp K. , Magendantz M. , Gusella J.F. , Tanzi R.E. , Solomon F.
Proc. Natl. Acad. Sci. U.S.A.89:10758-10762(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Retina.
3.

"Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I."
Beher D. , Hesse L. , Masters C.L. , Multhaup G.
J. Biol. Chem.271:1613-1620(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COLLAGEN-BINDING
4.

"Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1."
Homayouni R. , Rice D.S. , Sheldon M. , Curran T.
J. Neurosci.19:7507-7515(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DAB1
5.

"C-jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK."
Matsuda S. , Yasukawa T. , Homma Y. , Ito Y. , Niikura T. , Hiraki T. , Hirai S. , Ohno S. , Kita Y. , Kawasumi M. , Kouyama K. , Yamamoto T. , Kyriakis J.M. , Nishimoto I.
J. Neurosci.21:6597-6607(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MAPK8IP1
6.

"Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2."
Morris S.M. , Cooper J.A.
Traffic2:111-123(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DAB2
7.

"Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription."
Scheinfeld M.H. , Ghersi E. , Laky K. , Fowlkes B.J. , D'Adamio L.
J. Biol. Chem.277:44195-44201(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING BY GAMMA SECRETASE;INTERACTION WITH APBB1;MUTAGENESIS OF TYR-641
8.

"Crystal structures of the Dab homology domains of mouse disabled 1 and 2."
Yun M. , Keshvara L. , Park C.G. , Zhang Y.M. , Dickerson J.B. , Zheng J. , Rock C.O. , Curran T. , Park H.W.
J. Biol. Chem.278:36572-36581(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DAB1
9.

"Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation."
Cao Q. , Huang Y.-S. , Kan M.-C. , Richter J.D.
Mol. Cell. Biol.25:10930-10939(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CPEB1

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