Gene name:
AQR (KIAA0560) ;
Protein name:
Intron-binding protein aquarius ;
Alternative:
Intron-binding protein of 160 kDa (IBP160) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Identified in the spliceosome C complec.
Function:
Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Subcellular Location:
Nucleus
Localizes to speckle-like regions of the nucleoplasm.
Protein Attributes:
50:
MAAPAQPKKI | VAPTVSQINA | EFVTQLACKY | WAPHIKKKSP | FDIKVIEDIY |
100:
EKEIVKSRFA | IRKIMLLEFS | QYLENYLWMN | YSPEVSSKAY | LMSICCMVNE |
150:
KFRENVPAWE | IFKKKPDHFP | FFFKHILKAA | LAETDGEFSL | HEQTVLLLFL |
200:
DHCFNSLEVD | LIRSQVQQLI | SLPMWMGLQL | ARLELELKKT | PKLRKFWNLI |
250:
KKNDEKMDPE | AREQAYQERR | FLSQLIQKFI | SVLKSVPLSE | PVTMDKVHYC |
300:
ERFIELMIDL | EALLPTRRWF | NTILDDSHLL | VHCYLSNLVR | REEDGHLFSQ |
350:
LLDMLKFYTG | FEINDQTGNA | LTENEMTTIH | YDRITSLQRA | AFAHFPELYD |
400:
FALSNVAEVD | TRESLVKFFG | PLSSNTLHQV | ASYLCLLPTL | PKNEDTTFDK |
450:
EFLLELLVSR | HERRISQIQQ | LNQMPLYPTE | KIIWDENIVP | TEYYSGEGCL |
500:
ALPKLNLQFL | TLHDYLLRNF | NLFRLESTYE | IRQDIEDSVS | RMKPWQSEYG |
550:
GVVFGGWARM | AQPIVAFTVV | EVAKPNIGEN | WPTRVRADVT | INLNVRDHIK |
600:
DEWEGLRKHD | VCFLITVRPT | KPYGTKFDRR | RPFIEQVGLV | YVRGCEIQGM |
650:
LDDKGRVIED | GPEPRPNLRG | ESRTFRVFLD | PNQYQQDMTN | TIQNGAEDVY |
700:
ETFNIIMRRK | PKENNFKAVL | ETIRNLMNTD | CVVPDWLHDI | ILGYGDPSSA |
750:
HYSKMPNQIA | TLDFNDTFLS | IEHLKASFPG | HNVKVTVEDP | ALQIPPFRIT |
800:
FPVRSGKGKK | RKDADVEDED | TEEAKTLIVE | PHVIPNRGPY | PYNQPKRNTI |
850:
QFTHTQIEAI | RAGMQPGLTM | VVGPPGTGKT | DVAVQIISNI | YHNFPEQRTL |
900:
IVTHSNQALN | QLFEKIMALD | IDERHLLRLG | HGEEELETEK | DFSRYGRVNY |
950:
VLARRIELLE | EVKRLQKSLG | VPGDASYTCE | TAGYFFLYQV | MSRWEEYISK |
1000:
VKNKGSTLPD | VTEVSTFFPF | HEYFANAPQP | IFKGRSYEED | MEIAEGCFRH |
1050:
IKKIFTQLEE | FRASELLRSG | LDRSKYLLVK | EAKIIAMTCT | HAALKRHDLV |
1100:
KLGFKYDNIL | MEEAAQILEI | ETFIPLLLQN | PQDGFSRLKR | WIMIGDHHQL |
1150:
PPVIKNMAFQ | KYSNMEQSLF | TRFVRVGVPT | VDLDAQGRAR | ASLCNLYNWR |
1200:
YKNLGNLPHV | QLLPEFSTAN | AGLLYDFQLI | NVEDFQGVGE | SEPNPYFYQN |
1250:
LGEAEYVVAL | FMYMCLLGYP | ADKISILTTY | NGQKHLIRDI | INRRCGNNPL |
1300:
IGRPNKVTTV | DRFQGQQNDY | ILLSLVRTRA | VGHLRDVRRL | VVAMSRARLG |
1350:
LYIFARVSLF | QNCFELTPAF | SQLTARPLHL | HIIPTEPFPT | TRKNGERPSH |
1400:
EVQIIKNMPQ | MANFVYNMYM | HLIQTTHHYH | QTLLQLPPAM | VEEGEEVQNQ |
1450:
ETELETEEEA | MTVQADIIPS | PTDTSCRQET | PAFQTDTTPS | ETGATSTPEA |
1485:
IPALSETTPT | VVGAVSAPAE | ANTPQDATSA | PEETK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Intron-binding protein aquarius
ELISA Kit for Human Intron-binding protein aquarius
CLIA Kit for Human Intron-binding protein aquarius
CLIA Kit for Human Intron-binding protein aquarius
Polyclonal Antibody for Human Intron-binding protein aquarius
Polyclonal Antibody for Human Intron-binding protein aquarius
Monoclonal Antibody for Human Intron-binding protein aquarius
Monoclonal Antibody for Human Intron-binding protein aquarius
Protein for Human Intron-binding protein aquarius
Protein for Human Intron-binding protein aquarius
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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Brain .
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"The full-ORF clone resource of the German cDNA consortium."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Uterus .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE SPLICEOSOMAL C COMPLEX
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Cited for : FUNCTION;RNA-BINDING;SUBCELLULAR LOCATION
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Cited for : IDENTIFICATION AS PART OF THE XAB2 COMPLEX
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Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-1051;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]