Gene name:
Aqr (Kiaa0560) ;
Protein name:
Intron-binding protein aquarius ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Identified in the spliceosome C complex.
Function:
Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Subcellular Location:
Nucleus
Localizes to speckle-like regions of the nucleoplasm.
Protein Attributes:
50:
MAAPAQPKKI | VAPTVSQINA | EFVTQLACKY | WAPHIKKKSP | FDIKVIEEIY |
100:
EKEIVKSRFA | IRKIMLLEFS | QYLENYLWMN | YSPEVSSKAY | LMSICCMVNE |
150:
KFRENVPAWE | TFKKKPDHFP | FFFKCILKAA | LAETDGEFSL | HEQTLLLLFL |
200:
DHCFNSLEVD | LIRSQVQQLI | SLPMWMGLQP | ARLELELKKT | PKLRKFWNLI |
250:
KKNDEKMDPE | AREQAYQERR | FLSRLIQKFI | SVLKSIPLSE | PVTMDKVHYC |
300:
ERFIELMIDL | EALLPTRRWF | NTILDDSHLL | VHCYLSSLVH | REEDGHLFSQ |
350:
LLDMLKFYTG | FEINDQTGNA | LTENEMTTIH | YDRITSLQRA | AFAHFPELYD |
400:
FALSNVAEVD | ARDSLVKFFG | PLSSNTLHQV | ASYLCLLPTL | PKNEDTTFDK |
450:
EFLLELLVSR | HERRISQIQQ | LNQMPLYPTE | KIIWDENIVP | TEYYSGEGCL |
500:
ALPKLNLQFL | TLHDYLLRNF | NLFRLESTYE | IRQDIEDSVS | RMKPWQSEYG |
550:
GVVFGGWARM | AQPIVAFTVV | EVAKPNIGEN | WPTRVRADVT | INLNVRDHIK |
600:
DEWEGLRKHD | VCFLITVRPT | KPYGTKFDRR | RPFIEQVGLV | YVRGCEIQGM |
650:
LDDKGRVIED | GPEPRPNLRG | ESRTFRVFLD | PNQYQQDMTN | TIQNGAEDVY |
700:
DTFNVIMRRK | PKENNFKAVL | ETIRNLMNTD | CVVPDWLHDI | ILGYGDPSSA |
750:
HYSKMPNQIA | TLDFNDTFLS | IEHLKASFPG | HNVKVTVSDP | ALQIPPFRIT |
800:
FPVRSGKGKK | RKDADGEEDD | TEEAKTLIVE | PHVIPNRGPY | PYNQPKRNTI |
850:
QFTHTQIEAI | RAGMQPGLTM | VVGPPGTGKT | DVAVQIISNI | YHNFPEQRTL |
900:
IVTHSNQALN | QLFEKIMALD | IDERHLLRLG | HGEEELETEK | DFSRYGRVNY |
950:
VLARRIELLE | EVKRLQKSLG | VPGDASYTCE | TAGYFFLYQV | MSRWEEYMSR |
1000:
VKNSGTACPD | AAPDAAQVAT | FFPFHEYFAN | APQPIFKGRS | YEEDMEIAEG |
1050:
CFRHIKKIFT | QLEEFRASEL | LRSGLDRSKY | LLVKEAKIIA | MTCTHAALKR |
1100:
HDLVKLGFKY | DNILMEEAAQ | ILEIETFIPL | LLQNPQDGFS | RLKRWIMIGD |
1150:
HHQLPPVIKN | MAFQKYSNME | QSLFTRFVRV | GVPTVDLDAQ | GRARASLCNL |
1200:
YNWRYKNLGN | LPHVQLLPEF | STANAGLLYD | FQLINVEDFQ | GVGESEPNPY |
1250:
FYQNLGEAEY | VVALFMYMCL | LGYPADKISI | LTTYNGQKHL | IRDIINRRCG |
1300:
NNPLIGRPNK | VTTVDRFQGQ | QNDYILLSLV | RTRAVGHLRD | VRRLVVAMSR |
1350:
ARLGLYIFAR | VSLFQNCFEL | TPAFSQLTAR | PLHLHIIPTE | PFPTSRKNGE |
1400:
RPPHEVQVIK | NMPQMANFVY | NMYMHLIQTT | HHYHQTFLQL | PPAMVEEGEE |
1450:
GQSQETEMEA | EEETVSAQGN | LTPSPADASL | SQETPAAQPD | CSSQTEDTSA |
1481:
PCDIATAAEP | VSAAAEAATP | QDAESVPTET | E
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse Intron-binding protein aquarius
ELISA Kit for Mouse Intron-binding protein aquarius
CLIA Kit for Mouse Intron-binding protein aquarius
CLIA Kit for Mouse Intron-binding protein aquarius
Polyclonal Antibody for Mouse Intron-binding protein aquarius
Polyclonal Antibody for Mouse Intron-binding protein aquarius
Monoclonal Antibody for Mouse Intron-binding protein aquarius
Monoclonal Antibody for Mouse Intron-binding protein aquarius
Protein for Mouse Intron-binding protein aquarius
Protein for Mouse Intron-binding protein aquarius
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Bone marrow .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Eye .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 35-794;DEVELOPMENTAL STAGE;INDUCTION