Arf1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comArf1 ELISA Kit for Rat(Rattus norvegicus)

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Arf1 (Gene name),

ADP-ribosylation factor 1 (Protein name ), ARF1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Arf1;

Protein name:

ADP-ribosylation factor 1;

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with ARHGAP21, PSCD2, HERC1 and GGA1 (By similarity). Interacts with PRKCABP, ASAP2 and PIP5K1A. Interacts with ARFGAP1, which hydrolyzes GTP and thus, regulates its function.Interacts with PI4KB in the Golgi complex. Interacts with NCS1/FREQ in the Golgi and at the plasma membrane.

Function:

GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles.

Subcellular Location:

Golgi apparatus Cytoplasm perinuclear region

Protein Attributes:

Sequence length:

181

Sequence:

50:

100:

150:

181:

RNWYIQATCA | TSGDGLYEGL | DWLSNQLRNQ | K

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P84079

UniGene:

Rn.93735

KEGG:

rno:64310

Pfam:

PF00025

SMR:

P84079

Uniprot:

P84079

FOR

ELISA Kit for Rat ADP-ribosylation factor 1

CLIA Kit for Rat ADP-ribosylation factor 1

Polyclonal Antibody for Rat ADP-ribosylation factor 1

Monoclonal Antibody for Rat ADP-ribosylation factor 1

Protein for Rat ADP-ribosylation factor 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Interspecies relationships among ADP-ribosylation factors (ARFs): evidence of evolutionary pressure to maintain individual identities."
Price S.R. , Nightingale M.S. , Tsuchiya M. , Moss J. , Vaughan M.
Mol. Cell. Biochem.159:15-23(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pituitary.
3.

"ADP-ribosylation factor-directed GTPase-activating protein. Purification and partial characterization."
Makler V. , Cukierman E. , Rotman M. , Admon A. , Cassel D.
J. Biol. Chem.270:5232-5237(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ARFGAP1
4.

"Interaction of the PDZ domain of human PICK1 with class I ADP-ribosylation factors."
Takeya R. , Takeshige K. , Sumimoto H.
Biochem. Biophys. Res. Commun.267:149-155(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PRKCABP
5.

"Identification of a new Pyk2 target protein with Arf-GAP activity."
Andreev J. , Simon J.-P. , Sabatini D.D. , Kam J. , Plowman G. , Randazzo P.A. , Schlessinger J.
Mol. Cell. Biol.19:2338-2350(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ASAP2
6.

"Type I phosphatidylinositol 4-phosphate 5-kinase directly interacts with ADP-ribosylation factor 1 and is responsible for phosphatidylinositol 4,5-bisphosphate synthesis in the Golgi compartment."
Jones D.H. , Morris J.B. , Morgan C.P. , Kondo H. , Irvine R.F. , Cockcroft S.
J. Biol. Chem.275:13962-13966(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIP5K1B
7.

"The small GTPase Arf1 modulates Arp2/3-mediated actin polymerization via PICK1 to regulate synaptic plasticity."
Rocca D.L. , Amici M. , Antoniou A. , Suarez E.B. , Halemani N. , Murk K. , McGarvey J. , Jaafari N. , Mellor J.R. , Collingridge G.L. , Hanley J.G.
Neuron79:293-307(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PICK1 AND GRIA2;SUBCELLULAR LOCATION
8.

"The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms."
Greasley S.E. , Jhoti H. , Teahan C. , Solari R. , Fensome A. , Thomas G.M. , Cockcroft S. , Bax B.
Nat. Struct. Biol.2:797-806(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) IN COMPLEX WITH GDP

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