Protein name:
Rho guanine nucleotide exchange factor 9 ;
Alternative:
Rac/Cdc42 guanine nucleotide exchange factor 9 ;Collybistin ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with GPHN.
Function:
Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MQWIRGGSGM | LITGDSIVSA | EAVWDHVTMA | NRGVAFKAGD | VIKVLDASNK |
100:
DWWWGQIDDE | EGWFPASFVR | LWVNQEDGVE | EGPSDVQNGH | LDPNSDCLCL |
150:
GRPLQNRDQM | RANVINEIMS | TERHYIKHLK | DICEGYLKQC | RKRRDMFSDE |
200:
QLKVIFGNIE | DIYRFQMGFV | RDLEKQYNND | DPHLSEIGPC | FLEHQDGFWI |
250:
YSEYCNNHLD | ACMELSKLMK | DSRYQHFFEA | CRLLQQMIDI | AIDGFLLTPV |
300:
QKICKYPLQL | AELLKYTAQD | HSDYRYVAAA | LAVMRNVTQQ | INERKRRLEN |
350:
IDKIAQWQAS | VLDWEGDDIL | DRSSELIYTG | EMAWIYQPYG | RNQQRVFFLF |
400:
DHQMVLCKKD | LIRRDILYYK | GRIDMDKYEV | IDIEDGRDDD | FNVSMKNAFK |
450:
LHNKETEEVH | LFFAKKLEEK | IRWLRAFREE | RKMVQEDEKI | GFEISENQKR |
493:
QAAMTVRKAS | KQKGRVGEEE | NQSLELKRAC | EVLQRLWSPG | KKS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Rat
Mouse
Human
ELISA Kit for Rat Rho guanine nucleotide exchange factor 9
ELISA Kit for Rat Rho guanine nucleotide exchange factor 9
ELISA Kit for Rat Rho guanine nucleotide exchange factor 9
ELISA Kit for Rat Rho guanine nucleotide exchange factor 9
CLIA Kit for Rat Rho guanine nucleotide exchange factor 9
CLIA Kit for Rat Rho guanine nucleotide exchange factor 9
CLIA Kit for Rat Rho guanine nucleotide exchange factor 9
CLIA Kit for Rat Rho guanine nucleotide exchange factor 9
Polyclonal Antibody for Rat Rho guanine nucleotide exchange factor 9
Polyclonal Antibody for Rat Rho guanine nucleotide exchange factor 9
Polyclonal Antibody for Rat Rho guanine nucleotide exchange factor 9
Polyclonal Antibody for Rat Rho guanine nucleotide exchange factor 9
Monoclonal Antibody for Rat Rho guanine nucleotide exchange factor 9
Monoclonal Antibody for Rat Rho guanine nucleotide exchange factor 9
Monoclonal Antibody for Rat Rho guanine nucleotide exchange factor 9
Monoclonal Antibody for Rat Rho guanine nucleotide exchange factor 9
Protein for Rat Rho guanine nucleotide exchange factor 9
Protein for Rat Rho guanine nucleotide exchange factor 9
Protein for Rat Rho guanine nucleotide exchange factor 9
Protein for Rat Rho guanine nucleotide exchange factor 9
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION;INTERACTION WITH GPHN;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH GPHN;MUTAGENESIS OF ARG-107; ASP-108; ARG-111 AND GLU-117
3.
"The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering."
Harvey K.
,
Duguid I.C.
,
Alldred M.J.
,
Beatty S.E.
,
Ward H.
,
Keep N.H.
,
Lingenfelter S.E.
,
Pearce B.R.
,
Lundgren J.
,
Owen M.J.
,
Smart T.G.
,
Luescher B.
,
Rees M.I.
,
Harvey R.J.
J. Neurosci.24:5816-5826(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ALTERNATIVE SPLICING;FUNCTION;INTERACTION WITH GPHN;SUBCELLULAR LOCATION
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS) OF 10-411 IN COMPLEX WITH CDC42;MUTAGENESIS OF ARG-107; ASP-108; ARG-111 AND GLU-117