Gene name:
ARHGEF15 (KIAA0915) ;
Protein name:
Rho guanine nucleotide exchange factor 15 ;
Alternative:
Vsm-RhoGEF ;Ephexin-5 (E5) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with EPHB2 (By similarity). Interacts with EPHA4.
Function:
Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.
Subcellular Location:
Cell projection
dendrite
Expressed exclusively in dendrites of the developing hippocampus.
Protein Attributes:
50:
MSAQSLPAAT | PPTQKPPRII | RPRPPSRSRA | AQSPGPPHNG | SSPQELPRNS |
100:
NDAPTPMCTP | IFWEPPAASL | KPPALLPPSA | SRASLDSQTS | PDSPSSTPTP |
150:
SPVSRRSASP | EPAPRSPVPP | PKPSGSPCTP | LLPMAGVLAQ | NGSASAPGTV |
200:
RRLAGRFEGG | AEGRAQDADA | PEPGLQARAD | VNGEREAPLT | GSGSQENGAP |
250:
DAGLACPPCC | PCVCHTTRPG | LELRWVPVGG | YEEVPRVPRR | ASPLRTSRSR |
300:
PHPPSIGHPA | VVLTSYRSTA | ERKLLPLLKP | PKPTRVRQDA | TIFGDPPQPD |
350:
LDLLSEDGIQ | TGDSPDEAPQ | NTPPATVEGR | EEEGLEVLKE | QNWELPLQDE |
400:
PLYQTYRAAV | LSEELWGVGE | DGSPSPANAG | DAPTFPRPPG | PRNTLWQELP |
450:
AVQASGLLDT | LSPQERRMQE | SLFEVVTSEA | SYLRSLRLLT | DTFVLSQALR |
500:
DTLTPRDHHT | LFSNVQRVQG | VSERFLATLL | SRVRSSPHIS | DLCDVVHAHA |
550:
VGPFSVYVDY | VRNQQYQEET | YSRLMDTNVR | FSAELRRLQS | LPKCERLPLP |
600:
SFLLLPFQRI | TRLRMLLQNI | LRQTEEGSSR | QENAQKALGA | VSKIIERCSA |
650:
EVGRMKQTEE | LIRLTQRLRF | HKVKALPLVS | WSRRLEFQGE | LTELGCRRGG |
700:
VLFASRPRFT | PLCLLLFSDL | LLITQPKSGQ | RLQVLDYAHR | SLVQAQQVPD |
750:
PSGPPTFRLS | LLSNHQGRPT | HRLLQASSLS | DMQRWLGAFP | TPGPLPCSPD |
800:
TIYEDCDCSQ | ELCSESSAPA | KTEGRSLESR | AAPKHLHKTP | EGWLKGLPGA |
841:
FPAQLVCEVT | GEHERRRHLR | QNQRLLEAVG | SSSGTPNAPP | P
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Rho guanine nucleotide exchange factor 15
ELISA Kit for Human Rho guanine nucleotide exchange factor 15
CLIA Kit for Human Rho guanine nucleotide exchange factor 15
CLIA Kit for Human Rho guanine nucleotide exchange factor 15
Polyclonal Antibody for Human Rho guanine nucleotide exchange factor 15
Polyclonal Antibody for Human Rho guanine nucleotide exchange factor 15
Monoclonal Antibody for Human Rho guanine nucleotide exchange factor 15
Monoclonal Antibody for Human Rho guanine nucleotide exchange factor 15
Protein for Human Rho guanine nucleotide exchange factor 15
Protein for Human Rho guanine nucleotide exchange factor 15
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT PRO-831
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
3.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T.
,
Suzuki Y.
,
Nishikawa T.
,
Otsuki T.
,
Sugiyama T.
,
Irie R.
,
Wakamatsu A.
,
Hayashi K.
,
Sato H.
,
Nagai K.
,
Kimura K.
,
Makita H.
,
Sekine M.
,
Obayashi M.
,
Nishi T.
,
Shibahara T.
,
Tanaka T.
,
Ishii S.
,
Yamamoto J.
,
Saito K.
,
Kawai Y.
,
Isono Y.
,
Nakamura Y.
,
Nagahari K.
,
Murakami K.
,
Yasuda T.
,
Iwayanagi T.
,
Wagatsuma M.
,
Shiratori A.
,
Sudo H.
,
Hosoiri T.
,
Kaku Y.
,
Kodaira H.
,
Kondo H.
,
Sugawara M.
,
Takahashi M.
,
Kanda K.
,
Yokoi T.
,
Furuya T.
,
Kikkawa E.
,
Omura Y.
,
Abe K.
,
Kamihara K.
,
Katsuta N.
,
Sato K.
,
Tanikawa M.
,
Yamazaki M.
,
Ninomiya K.
,
Ishibashi T.
,
Yamashita H.
,
Murakawa K.
,
Fujimori K.
,
Tanai H.
,
Kimata M.
,
Watanabe M.
,
Hiraoka S.
,
Chiba Y.
,
Ishida S.
,
Ono Y.
,
Takiguchi S.
,
Watanabe S.
,
Yosida M.
,
Hotuta T.
,
Kusano J.
,
Kanehori K.
,
Takahashi-Fujii A.
,
Hara H.
,
Tanase T.-O.
,
Nomura Y.
,
Togiya S.
,
Komai F.
,
Hara R.
,
Takeuchi K.
,
Arita M.
,
Imose N.
,
Musashino K.
,
Yuuki H.
,
Oshima A.
,
Sasaki N.
,
Aotsuka S.
,
Yoshikawa Y.
,
Matsunawa H.
,
Ichihara T.
,
Shiohata N.
,
Sano S.
,
Moriya S.
,
Momiyama H.
,
Satoh N.
,
Takami S.
,
Terashima Y.
,
Suzuki O.
,
Nakagawa S.
,
Senoh A.
,
Mizoguchi H.
,
Goto Y.
,
Shimizu F.
,
Wakebe H.
,
Hishigaki H.
,
Watanabe T.
,
Sugiyama A.
,
Takemoto M.
,
Kawakami B.
,
Yamazaki M.
,
Watanabe K.
,
Kumagai A.
,
Itakura S.
,
Fukuzumi Y.
,
Fujimori Y.
,
Komiyama M.
,
Tashiro H.
,
Tanigami A.
,
Fujiwara T.
,
Ono T.
,
Yamada K.
,
Fujii Y.
,
Ozaki K.
,
Hirao M.
,
Ohmori Y.
,
Kawabata A.
,
Hikiji T.
,
Kobatake N.
,
Inagaki H.
,
Ikema Y.
,
Okamoto S.
,
Okitani R.
,
Kawakami T.
,
Noguchi S.
,
Itoh T.
,
Shigeta K.
,
Senba T.
,
Matsumura K.
,
Nakajima Y.
,
Mizuno T.
,
Morinaga M.
,
Sasaki M.
,
Togashi T.
,
Oyama M.
,
Hata H.
,
Watanabe M.
,
Komatsu T.
,
Mizushima-Sugano J.
,
Satoh T.
,
Shirai Y.
,
Takahashi Y.
,
Nakagawa K.
,
Okumura K.
,
Nagase T.
,
Nomura N.
,
Kikuchi H.
,
Masuho Y.
,
Yamashita R.
,
Nakai K.
,
Yada T.
,
Nakamura Y.
,
Ohara O.
,
Isogai T.
,
Sugano S.
more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS PRO-277 AND PRO-831
tissue :
Placenta .
4.
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C.
,
Garber M.
,
Adams D.J.
,
Sharpe T.
,
Harrow J.
,
Lupski J.R.
,
Nicholson C.
,
Searle S.M.
,
Wilming L.
,
Young S.K.
,
Abouelleil A.
,
Allen N.R.
,
Bi W.
,
Bloom T.
,
Borowsky M.L.
,
Bugalter B.E.
,
Butler J.
,
Chang J.L.
,
Chen C.-K.
,
Cook A.
,
Corum B.
,
Cuomo C.A.
,
de Jong P.J.
,
DeCaprio D.
,
Dewar K.
,
FitzGerald M.
,
Gilbert J.
,
Gibson R.
,
Gnerre S.
,
Goldstein S.
,
Grafham D.V.
,
Grocock R.
,
Hafez N.
,
Hagopian D.S.
,
Hart E.
,
Norman C.H.
,
Humphray S.
,
Jaffe D.B.
,
Jones M.
,
Kamal M.
,
Khodiyar V.K.
,
LaButti K.
,
Laird G.
,
Lehoczky J.
,
Liu X.
,
Lokyitsang T.
,
Loveland J.
,
Lui A.
,
Macdonald P.
,
Major J.E.
,
Matthews L.
,
Mauceli E.
,
McCarroll S.A.
,
Mihalev A.H.
,
Mudge J.
,
Nguyen C.
,
Nicol R.
,
O'Leary S.B.
,
Osoegawa K.
,
Schwartz D.C.
,
Shaw-Smith C.
,
Stankiewicz P.
,
Steward C.
,
Swarbreck D.
,
Venkataraman V.
,
Whittaker C.A.
,
Yang X.
,
Zimmer A.R.
,
Bradley A.
,
Hubbard T.
,
Birren B.W.
,
Rogers J.
,
Lander E.S.
,
Nusbaum C.
more...
Nature440:1045-1049(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
Mural R.J.
,
Istrail S.
,
Sutton G.G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
,
Walenz B.
,
Shatkay H.
,
Dew I.
,
Miller J.R.
,
Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANTS PRO-277 AND PRO-831
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS VAL-155; PRO-277 AND PRO-831
tissue :
Lung .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;PHOSPHORYLATION;INTERACTION WITH EPHA4;REGULATION