Gene name:
Rad54l2 (Arip4;Srisnf2l) ;
Protein name:
Helicase ARIP4 ;
Alternative:
RAD54-like protein 2 ;Androgen receptor-interacting protein 4 ;Steroid receptor-interacting SNF2 domain-containing protein-like ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with AR via its N-terminus. Interacts with DYRK1A. Binds DNA and mononucleosomes, but does not seem to form large multiprotein complexes.
Function:
DNA helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. Not able to remodel mononucleosomes in vitro. Acts as an AR-coregulator in Sertoli cells.
Subcellular Location:
Nucleus
Localizes in speckle-like nuclear compartments.
Protein Attributes:
50:
MSDESASGSD | PDLDPDVELE | DEEEEEEEEE | VAVEEHDRDD | EEGLLDDTSL |
100:
EGMCGTEHAQ | LGEDGQRPPR | CTSTTSSQSE | PSEQLRHQGK | ILASEDPKKK |
150:
RAQKPSHMRR | NIRKLLREDQ | LEPVTKAAQQ | EELERRKRLE | QQRKEYAAPI |
200:
PTVPLEFLPE | EIVLRASDGP | QLPPRVLAQE | VICLDSSSGS | EDEKSSRDEV |
250:
IELSSGEEDT | LHIVDSSESV | SEEDEEEEKG | GTHVNDALNQ | HDALGRVLVN |
300:
LNHPPEEENV | FLAPQLARAV | KPHQIGGIRF | LYDNLVESLE | RFKTSSGFGC |
350:
ILAHSMGLGK | TLQVISFIDV | LFRHTPAKTV | LAIVPVNTLQ | NWLAEFNMWL |
400:
PAPEALPADS | KPEEVQPRFF | KVHILNDEHK | TVASRAKVTA | DWVSEGGVLL |
450:
MGYEMYRLLT | LKKSLATSRP | KKTKKRSHPV | IIDLDEEDRQ | QEFRREFEKA |
500:
LCRPGPDVVI | CDEGHRIKNC | QASTSQALKN | IRSRRRVVLT | GYPLQNNLIE |
550:
YWCMVDFVRP | DFLGTRQEFS | NMFERPILNG | QCIDSTPQDV | RLMRYRSHVL |
600:
HSLLEGFVQR | RGHTVLKIHL | PAKEENVILV | RLSQIQRDLY | TQFMDRFRDC |
650:
GTSGWLGLNP | LKAFCVCCKI | WNHPDVLYEA | LQKENLANEQ | DLDVEELGSA |
700:
GTSARCPPHG | TKVKGEDSAL | PSSMGEATNS | KFLQGVGFNP | FQERGNNIVT |
750:
YEWAKELLTN | YQTGVLENSP | KMVLLFHLIE | ESVKLGDKIL | VFSQSLSTLA |
800:
LIEEFLGKRD | MPCLPGAEGQ | GTQKWVRNVS | YFRLDGSTPA | FERERLINQF |
850:
NDPSNLTTWL | FLLSTRAGCL | GVNLIGANRV | VVFDASWNPC | HDAQAVCRVY |
900:
RYGQKKPCHI | YRLVADYTLE | KKIYDRQISK | QGMSDRVVDD | LNPMLNFTRK |
950:
EVENLLHFVE | KEPAPQTSLD | IKGIKESVLQ | LACLKYPHLI | TKEPFEHESL |
1000:
LLNRKDHKLT | KAEKKAAKKS | YEEDKRTSVP | YTRPSYAQYY | PASDQSLTSI |
1050:
PAFSQRNWQP | TLKGDEKPVA | SVRPVQSTPI | PMMPRHVPLS | GGVSSASSTN |
1100:
TSMNFPINYL | QRAGVLVQKV | VTTTDIVIPG | LNSSTDVQAR | INAGESIHII |
1150:
RGTKGTYIRT | SDGRIFAVRA | TGKPKAPEDG | RMAASGSQGP | SLASTSNGRH |
1200:
SASSPKAPDP | EGLARPVSPD | SPEIISELQQ | YADVAAARES | RQSSPSISAA |
1250:
LPGPPGQLMD | NSTIPGTALG | TEPCLGGHCL | NSSLLVTGQP | SGGRHPVLDL |
1300:
RGHKRKLATP | SVTQESIRRR | SRKGHLPAPV | QPYEHGYPVS | GGFAMPPVSL |
1350:
NHNLTTPFTS | QAGENSLFMG | SNPSYYQLSN | LLADARLVFP | VTTDPLVPAG |
1400:
PVSSSSTATS | VTASNPSFML | NPSVPGMLPS | YSLPFSQPLL | SEPRMFAPFP |
1450:
SPGLPSNLSR | GVSVYPGYMS | PHAGYPAGGL | LRSQVPPFDS | HEVAEVGFSS |
1466:
NDDEDKDDDV | IEVTGK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Helicase ARIP4
ELISA Kit for Mouse Helicase ARIP4
CLIA Kit for Mouse Helicase ARIP4
CLIA Kit for Mouse Helicase ARIP4
Polyclonal Antibody for Mouse Helicase ARIP4
Polyclonal Antibody for Mouse Helicase ARIP4
Monoclonal Antibody for Mouse Helicase ARIP4
Monoclonal Antibody for Mouse Helicase ARIP4
Protein for Mouse Helicase ARIP4
Protein for Mouse Helicase ARIP4
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;DNA-BINDING;INTERACTION WITH AR;MUTAGENESIS OF LYS-310 AND 462-ASP-GLU-463
strain :
Swiss Webster .
tissue :
Embryo .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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"The transcriptional landscape of the mammalian genome."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 33-1466
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH DYRK1A
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES;ENZYME REGULATION;INTERACTION WITH AR;SUMOYLATION;MUTAGENESIS OF LYS-361; LYS-573; LYS-664; LYS-935; LYS-961 AND LYS-1013
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE