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Index > Protein center > Rad54l2(Gene name) > Mouse
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  • Rad54l2 (Gene name),
  • Helicase ARIP4 (Protein name ),  ARIP4_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Rad54l2(Arip4;Srisnf2l);
    Protein name:
    Helicase ARIP4;
    Alternative:
    RAD54-like protein 2;Androgen receptor-interacting protein 4;Steroid receptor-interacting SNF2 domain-containing protein-like;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with AR via its N-terminus. Interacts with DYRK1A. Binds DNA and mononucleosomes, but does not seem to form large multiprotein complexes.
    Function:
    DNA helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. Not able to remodel mononucleosomes in vitro. Acts as an AR-coregulator in Sertoli cells.
    Subcellular Location:
    Nucleus Localizes in speckle-like nuclear compartments.
    Protein Attributes:
    Sequence length:
    1466
    Sequence:
    50:
    MSDESASGSD | PDLDPDVELE | DEEEEEEEEE | VAVEEHDRDD | EEGLLDDTSL | 
    100:
    EGMCGTEHAQ | LGEDGQRPPR | CTSTTSSQSE | PSEQLRHQGK | ILASEDPKKK | 
    150:
    RAQKPSHMRR | NIRKLLREDQ | LEPVTKAAQQ | EELERRKRLE | QQRKEYAAPI | 
    200:
    PTVPLEFLPE | EIVLRASDGP | QLPPRVLAQE | VICLDSSSGS | EDEKSSRDEV | 
    250:
    IELSSGEEDT | LHIVDSSESV | SEEDEEEEKG | GTHVNDALNQ | HDALGRVLVN | 
    300:
    LNHPPEEENV | FLAPQLARAV | KPHQIGGIRF | LYDNLVESLE | RFKTSSGFGC | 
    350:
    ILAHSMGLGK | TLQVISFIDV | LFRHTPAKTV | LAIVPVNTLQ | NWLAEFNMWL | 
    400:
    PAPEALPADS | KPEEVQPRFF | KVHILNDEHK | TVASRAKVTA | DWVSEGGVLL | 
    450:
    MGYEMYRLLT | LKKSLATSRP | KKTKKRSHPV | IIDLDEEDRQ | QEFRREFEKA | 
    500:
    LCRPGPDVVI | CDEGHRIKNC | QASTSQALKN | IRSRRRVVLT | GYPLQNNLIE | 
    550:
    YWCMVDFVRP | DFLGTRQEFS | NMFERPILNG | QCIDSTPQDV | RLMRYRSHVL | 
    600:
    HSLLEGFVQR | RGHTVLKIHL | PAKEENVILV | RLSQIQRDLY | TQFMDRFRDC | 
    650:
    GTSGWLGLNP | LKAFCVCCKI | WNHPDVLYEA | LQKENLANEQ | DLDVEELGSA | 
    700:
    GTSARCPPHG | TKVKGEDSAL | PSSMGEATNS | KFLQGVGFNP | FQERGNNIVT | 
    750:
    YEWAKELLTN | YQTGVLENSP | KMVLLFHLIE | ESVKLGDKIL | VFSQSLSTLA | 
    800:
    LIEEFLGKRD | MPCLPGAEGQ | GTQKWVRNVS | YFRLDGSTPA | FERERLINQF | 
    850:
    NDPSNLTTWL | FLLSTRAGCL | GVNLIGANRV | VVFDASWNPC | HDAQAVCRVY | 
    900:
    RYGQKKPCHI | YRLVADYTLE | KKIYDRQISK | QGMSDRVVDD | LNPMLNFTRK | 
    950:
    EVENLLHFVE | KEPAPQTSLD | IKGIKESVLQ | LACLKYPHLI | TKEPFEHESL | 
    1000:
    LLNRKDHKLT | KAEKKAAKKS | YEEDKRTSVP | YTRPSYAQYY | PASDQSLTSI | 
    1050:
    PAFSQRNWQP | TLKGDEKPVA | SVRPVQSTPI | PMMPRHVPLS | GGVSSASSTN | 
    1100:
    TSMNFPINYL | QRAGVLVQKV | VTTTDIVIPG | LNSSTDVQAR | INAGESIHII | 
    1150:
    RGTKGTYIRT | SDGRIFAVRA | TGKPKAPEDG | RMAASGSQGP | SLASTSNGRH | 
    1200:
    SASSPKAPDP | EGLARPVSPD | SPEIISELQQ | YADVAAARES | RQSSPSISAA | 
    1250:
    LPGPPGQLMD | NSTIPGTALG | TEPCLGGHCL | NSSLLVTGQP | SGGRHPVLDL | 
    1300:
    RGHKRKLATP | SVTQESIRRR | SRKGHLPAPV | QPYEHGYPVS | GGFAMPPVSL | 
    1350:
    NHNLTTPFTS | QAGENSLFMG | SNPSYYQLSN | LLADARLVFP | VTTDPLVPAG | 
    1400:
    PVSSSSTATS | VTASNPSFML | NPSVPGMLPS | YSLPFSQPLL | SEPRMFAPFP | 
    1450:
    SPGLPSNLSR | GVSVYPGYMS | PHAGYPAGGL | LRSQVPPFDS | HEVAEVGFSS | 
    1466:
    NDDEDKDDDV | IEVTGK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    KEGG:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Helicase ARIP4
    ELISA Kit for Mouse Helicase ARIP4
    CLIA Kit for Mouse Helicase ARIP4
    CLIA Kit for Mouse Helicase ARIP4
    Polyclonal Antibody for Mouse Helicase ARIP4
    Polyclonal Antibody for Mouse Helicase ARIP4
    Monoclonal Antibody for Mouse Helicase ARIP4
    Monoclonal Antibody for Mouse Helicase ARIP4
    Protein for Mouse Helicase ARIP4
    Protein for Mouse Helicase ARIP4

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Novel ATPase of SNF2-like protein family interacts with androgen receptor and modulates androgen-dependent transcription."
      Rouleau N. , Domans'kyi A. , Reeben M. , Moilanen A.-M. , Havas K. , Kang Z. , Owen-Hughes T. , Palvimo J.J. , Jaenne O.A.
      Mol. Biol. Cell13:2106-2119(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;DNA-BINDING;INTERACTION WITH AR;MUTAGENESIS OF LYS-310 AND 462-ASP-GLU-463
      strain: Swiss Webster.
      tissue: Embryo.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 33-1466
      strain: C57BL/6J.
    4. 4.
      "Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4."
      Sitz J.H. , Tigges M. , Baumgaertel K. , Khaspekov L.G. , Lutz B.
      Mol. Cell. Biol.24:5821-5834(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH DYRK1A
    5. 5.
      "Biochemical characterization of androgen receptor-interacting protein 4."
      Domanskyi A. , Virtanen K.T. , Palvimo J.J. , Jaenne O.A.
      Biochem. J.393:789-795(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES;ENZYME REGULATION;INTERACTION WITH AR;SUMOYLATION;MUTAGENESIS OF LYS-361; LYS-573; LYS-664; LYS-935; LYS-961 AND LYS-1013
    6. 6.
      "Expression and localization of androgen receptor-interacting protein-4 in the testis."
      Domanskyi A. , Zhang F.-P. , Nurmio M. , Palvimo J.J. , Toppari J. , Jaenne O.A.
      Am. J. Physiol.292:E513-E522(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    7. 7.
      "An adenosine triphosphatase of the sucrose nonfermenting 2 family, androgen receptor-interacting protein 4, is essential for mouse embryonic development and cell proliferation."
      Zhang F.-P. , Domanskyi A. , Palvimo J.J. , Sariola H. , Partanen J. , Jaenne O.A.
      Mol. Endocrinol.21:1430-1442(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE
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