Akr7a2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAkr7a2 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Akr7a2(Gene name) > Rat

Akr7a2 (Gene name),

Aflatoxin B1 aldehyde reductase member 2 (Protein name ), ARK72_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Akr7a2(Afar2;Aiar);

Protein name:

Aflatoxin B1 aldehyde reductase member 2(rAFAR2);

Alternative:

Succinic semialdehyde reductase(SSA reductase);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer. Heterodimer with AKR7A1.

Function:

Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. Acts as a 2-carboxybenzaldehyde reductase.

Subcellular Location:

Golgi apparatus Golgi stack Cytoplasm Its association with the Golgi stack may facilitate secretion of GHB.

Protein Attributes:

Sequence length:

367

Sequence:

50:

100:

150:

200:

250:

300:

350:

367:

FNQAWNVVAH | ECPNYFR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q8CG45

Pfam:

PF00248

UniGene:

Rn.8548

KEGG:

rno:171445

Uniprot:

Q8CG45

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ELISA Kit for Rat rAFAR2

Cat.:

E15236h

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96T

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ELISA Kit for Rat rAFAR2

Cat.:

E15236m

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96T

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ELISA Kit for Rat rAFAR2

Cat.:

E15236r

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96T

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CLIA Kit for Rat rAFAR2

Cat.:

U15236r

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96T

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CLIA Kit for Rat rAFAR2

Cat.:

U15236m

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96T

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CLIA Kit for Rat rAFAR2

Cat.:

U15236h

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Packing:

96T

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Polyclonal Antibody for Rat rAFAR2

Cat.:

P15236Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat rAFAR2

Cat.:

P15236Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat rAFAR2

Cat.:

P15236Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat rAFAR2

Protein for Rat rAFAR2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins."
Kelly V.P. , Sherratt P.J. , Crouch D.H. , Hayes J.D.
Biochem. J.366:847-861(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 4-14 AND 33-44;FUNCTION;SUBUNIT;COFACTOR;SUBCELLULAR LOCATION
strain: Fischer 344.
tissue: Liver.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 11-367
tissue: Prostate.
3.

"Aflatoxin B1 aldehyde reductase (AFAR) genes cluster at 1p35-1p36.1 in a region frequently altered in human tumour cells."
Praml C. , Savelyeva L. , Schwab M.
Oncogene22:4765-4773(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 11-367
4.

"Androgen-regulated expression of a novel member of the aldo-keto reductase superfamily in regrowing rat prostate."
Nishi N. , Shoji H. , Miyanaka H. , Nakamura T.
Endocrinology141:3194-3199(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 12-367
strain: Sprague-Dawley.
5.

Lubec G. , Afjehi-Sadat L.
Submitted (2006-11) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 230-244; 259-269 AND 306-317;IDENTIFICATION BY MASS SPECTROMETRY
strain: Sprague-Dawley.
tissue: Spinal cord.

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