Protein name:
ADP-ribosylation factor-like protein 3 ;
Alternative:
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Found in a complex with ARL3, RP2 and UNC119; RP2 induces hydrolysis of GTP ARL3 in the complex, leading to the release of UNC119. Interacts with SYS1 and SCOC. Interacts with ARL2BP; the GTP-bound form interacts with ARL2BP. Interacts with RP2; interaction is direct and stimulated with the activated GTP-bound form of ARL3. Microtubule-associated protein. Does not interact with TBCC. Interacts with RP2 and PDE6D. Interacts with PDE6D; the interaction occurs specifically with the GTP-bound form of ARL3.
Function:
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for normal cytokinesis.
Subcellular Location:
Golgi apparatus membrane
Peripheral membrane protein
Cytoplasmic side
Cytoplasm
cytoskeleton
spindle
Nucleus
Cytoplasm
cytoskeleton
centrosome
Cytoplasm
Cell projection
cilium
Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. Present on the mitotic spindle.
Protein Attributes:
50:
MGLLSILRKL | KSAPDQEVRI | LLLGLDNAGK | TTLLKQLASE | DISHITPTQG |
100:
FNIKSVQSQG | FKLNVWDIGG | QRKIRPYWRN | YFENTDILIY | VIDSADRKRF |
150:
EETGQELAEL | LEEEKLSCVP | VLIFANKQDL | LTAAPASEIA | EGLNLHTIRD |
182:
RVWQIQSCSA | LTGEGVQDGM | NWVCKNVNAK | KK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Bovine
Pig
Rat
ELISA Kit for Pig ADP-ribosylation factor-like protein 3
ELISA Kit for Pig ADP-ribosylation factor-like protein 3
ELISA Kit for Pig ADP-ribosylation factor-like protein 3
ELISA Kit for Pig ADP-ribosylation factor-like protein 3
ELISA Kit for Pig ADP-ribosylation factor-like protein 3
CLIA Kit for Pig ADP-ribosylation factor-like protein 3
CLIA Kit for Pig ADP-ribosylation factor-like protein 3
CLIA Kit for Pig ADP-ribosylation factor-like protein 3
CLIA Kit for Pig ADP-ribosylation factor-like protein 3
CLIA Kit for Pig ADP-ribosylation factor-like protein 3
Polyclonal Antibody for Pig ADP-ribosylation factor-like protein 3
Polyclonal Antibody for Pig ADP-ribosylation factor-like protein 3
Polyclonal Antibody for Pig ADP-ribosylation factor-like protein 3
Polyclonal Antibody for Pig ADP-ribosylation factor-like protein 3
Polyclonal Antibody for Pig ADP-ribosylation factor-like protein 3
Monoclonal Antibody for Pig ADP-ribosylation factor-like protein 3
Monoclonal Antibody for Pig ADP-ribosylation factor-like protein 3
Monoclonal Antibody for Pig ADP-ribosylation factor-like protein 3
Monoclonal Antibody for Pig ADP-ribosylation factor-like protein 3
Monoclonal Antibody for Pig ADP-ribosylation factor-like protein 3
Protein for Pig ADP-ribosylation factor-like protein 3
Protein for Pig ADP-ribosylation factor-like protein 3
Protein for Pig ADP-ribosylation factor-like protein 3
Protein for Pig ADP-ribosylation factor-like protein 3
Protein for Pig ADP-ribosylation factor-like protein 3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]