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Index > Protein center > ACTR3B(Gene name) > Human
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  • ACTR3B (Gene name),
  • Actin-related protein 3B (Protein name ),  ARP3B_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    ACTR3B(ARP11;ARP4);
    Protein name:
    Actin-related protein 3B;
    Alternative:
    Actin-like protein 3B;ARP3-beta;Actin-related protein ARP4;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with the Arp2/3 complex composed of ARP2, ARP3, ARPC1B, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.
    Function:
    Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.
    Subcellular Location:
    Cytoplasm cytoskeleton Cell projection
    Protein Attributes:
    Sequence length:
    418
    Sequence:
    50:
    MAGSLPPCVV | DCGTGYTKLG | YAGNTEPQFI | IPSCIAIRES | AKVVDQAQRR | 
    100:
    VLRGVDDLDF | FIGDEAIDKP | TYATKWPIRH | GIIEDWDLME | RFMEQVVFKY | 
    150:
    LRAEPEDHYF | LMTEPPLNTP | ENREYLAEIM | FESFNVPGLY | IAVQAVLALA | 
    200:
    ASWTSRQVGE | RTLTGIVIDS | GDGVTHVIPV | AEGYVIGSCI | KHIPIAGRDI | 
    250:
    TYFIQQLLRE | REVGIPPEQS | LETAKAIKEK | YCYICPDIVK | EFAKYDVDPR | 
    300:
    KWIKQYTGIN | AINQKKFVID | VGYERFLGPE | IFFHPEFANP | DFMESISDVV | 
    350:
    DEVIQNCPID | VRRPLYKNVV | LSGGSTMFRD | FGRRLQRDLK | RVVDARLRLS | 
    400:
    EELSGGRIKP | KPVEVQVVTH | HMQRYAVWFG | GSMLASTPEF | FQVCHTKKDY | 
    418:
    EEYGPSICRH | NPVFGVMS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    SMR:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Actin-related protein 3B
    ELISA Kit for Human Actin-related protein 3B
    CLIA Kit for Human Actin-related protein 3B
    CLIA Kit for Human Actin-related protein 3B
    Polyclonal Antibody for Human Actin-related protein 3B
    Polyclonal Antibody for Human Actin-related protein 3B
    Monoclonal Antibody for Human Actin-related protein 3B
    Monoclonal Antibody for Human Actin-related protein 3B
    Protein for Human Actin-related protein 3B
    Protein for Human Actin-related protein 3B

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "ARP3beta, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells."
      Jay P. , Berge-Lefranc J.-L. , Massacrier A. , Roessler E. , Wallis D. , Muenke M. , Gastaldi M. , Taviaux S. , Cau P. , Berta P.
      Eur. J. Biochem.267:2921-2928(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);ALTERNATIVE SPLICING;TISSUE SPECIFICITY
      tissue: Embryo.
    2. 2.
      "Cloning of a novel human cDNA homology to human actin-related protein Arp3(ARP3) mRNA."
      Ding J.B. , Yu L. , Zhang M. , Dai F.Y. , Jiang J.X. , Zhao S.Y.
      Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Amygdala.
      tissue: Peripheral blood.
    4. 4.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
      tissue: Colon.
      tissue: Skin.
    6. 6.
      "Isolation of a novel actin-related gene expressed in low-metastatic PC-14 human lung adenocarcinoma."
      Shindo-Okada N. , Shimizu K.
      Biochem. Biophys. Res. Commun.280:61-67(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    7. 7.
      "Expression of the Arp11 gene suppresses the tumorigenicity of PC-14 human lung adenocarcinoma cells."
      Shindo-Okada N. , Iigo M.
      Biochem. Biophys. Res. Commun.312:889-896(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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