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Index > Protein center > ARPIN(Gene name) > Bovine
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  • ARPIN (Gene name),
  • Arpin (Protein name ),  ARPIN_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ARPIN;
    Protein name:
    Arpin;
    Alternative:

    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Associates with the Arp2/3 complex. Interacts with ARPC2; enhanced by activated RAC1. Interacts with ARPC5; the interaction is dependent on RAC1.
    Function:
    Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence.
    Subcellular Location:
    Cell projection Lamellipodium Colocalized with the WAVE complex at lamelliupodium tip.
    Protein Attributes:
    Sequence length:
    226
    Sequence:
    50:
    MSRIYQDSAL | RNKAVRSARL | PGAWDPAAHQ | RGDGVLLEGE | LLDVSRHSIL | 
    100:
    DAHGRKERYY | VLYIRPSRIH | RRKFDPKGNE | IEPNFSATRK | VNTGFLMSSY | 
    150:
    KVEAKGDSDR | LTPEALKGLV | NKPELLALTE | SLTPAETVAF | WMPESEMEAM | 
    200:
    ELELGAGVRL | KTRGDGPFLD | SLAKLEAGTV | TKCNFAGDGK | TGASWTDNIM | 
    226:
    AQKSSEGAAS | ETREQGDGAA | DEEWDD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Arpin
    ELISA Kit for Bovine Arpin
    ELISA Kit for Bovine Arpin
    CLIA Kit for Bovine Arpin
    CLIA Kit for Bovine Arpin
    CLIA Kit for Bovine Arpin
    Polyclonal Antibody for Bovine Arpin
    Polyclonal Antibody for Bovine Arpin
    Polyclonal Antibody for Bovine Arpin
    Monoclonal Antibody for Bovine Arpin
    Monoclonal Antibody for Bovine Arpin
    Monoclonal Antibody for Bovine Arpin
    Protein for Bovine Arpin
    Protein for Bovine Arpin
    Protein for Bovine Arpin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Hippocampus.
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