Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (Protein name
), ASAP1_RAT from NCBI database.
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General Annotation
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Antigen Annotation
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Predicted Eptitope
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Gene name:
Asap1(Ddef1);
Protein name:
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1;
Alternative:
ADP-ribosylation factor-directed GTPase-activating protein 1(ARF GTPase-activating protein 1);130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein;PIP2-dependent ARF1 GAP;Development and differentiation-enhancing factor 1(DEF-1;Differentiation-enhancing factor 1);
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homodimer. Interacts with SRC and CRK. Interacts with RAB11FIP3.
Function:
Possesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types. Plays a role in ciliogenesis.
ELISA Kit for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
ELISA Kit for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
ELISA Kit for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
ELISA Kit for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
CLIA Kit for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
CLIA Kit for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
CLIA Kit for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
CLIA Kit for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Polyclonal Antibody for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Polyclonal Antibody for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Polyclonal Antibody for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Polyclonal Antibody for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Monoclonal Antibody for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Monoclonal Antibody for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Monoclonal Antibody for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Monoclonal Antibody for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Protein for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Protein for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Protein for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Protein for Rat Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Enhanced ASAP1 expression is associated with tumor development and progression, and promotes metastasis in experimental tumors." Mueller T.
,
Rothley M.
,
Bauer M.
,
Pankraz M.
,
Sleeman J.
Submitted (2005-10) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3)