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Index > Protein center > Ascl1(Gene name) > Mouse
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  • Ascl1 (Gene name),
  • Achaete-scute homolog 1 (Protein name ),  ASCL1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ascl1(Ash1;Mash-1;Mash1);
    Protein name:
    Achaete-scute homolog 1(ASH-1;mASH-1;mASH1);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with TCF3.
    Function:
    Transcriptional regulator. May play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Involved in the initiation of neuronal differentiation. Mediates transcription activation by binding to the E box (5'-CANNTG-3').
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    231
    Sequence:
    50:
    MESSGKMESG | AGQQPQPPQP | FLPPAACFFA | TAAAAAAAAA | AAAQSAQQQQ | 
    100:
    PQAPPQQAPQ | LSPVADSQPS | GGGHKSAAKQ | DKRQRSSSPE | LMRCKRRLNF | 
    150:
    SGFGYSLPQQ | QPAAVARRNE | RERNRVKLVN | LGFATLREHV | PNGAANKKMS | 
    200:
    KVETLRSAVQ | YIRALQQLLD | EHDAVSAAFQ | AGVLSPTISP | NYSNDLNSMA | 
    231:
    GSPVSSYSSD | EGSYDPLSPE | EQELLDFTNW | F
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ASH-1
    Cat.:
    E15118h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse ASH-1
    Cat.:
    E15118r
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse ASH-1
    Cat.:
    E15118m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse ASH-1
    Cat.:
    U15118h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ASH-1
    Cat.:
    U15118m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ASH-1
    Cat.:
    U15118r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse ASH-1
    Cat.:
    P15118Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ASH-1
    Cat.:
    P15118Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ASH-1
    Cat.:
    P15118Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse ASH-1
    Monoclonal Antibody for Mouse ASH-1
    Monoclonal Antibody for Mouse ASH-1
    Protein for Mouse ASH-1
    Protein for Mouse ASH-1
    Protein for Mouse ASH-1

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    Linearity
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    References
    1. 1.
      "Cloning, sequencing and expression of the mouse mammalian achaete-scute homolog 1 (MASH1)."
      del Amo F. , Gendron-Maguire M. , Gridley T.
      Biochim. Biophys. Acta1171:323-327(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    2. 2.
      "Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system."
      Guillemot F. , Joyner A.L.
      Mech. Dev.42:171-185(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Eye.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    5. 5.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
    7. 7.
      "Generation of neurons by transient expression of neural bHLH proteins in mammalian cells."
      Farah M.H. , Olson J.M. , Sucic H.B. , Hume R.I. , Tapscott S.J. , Turner D.L.
      Development127:693-702(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DNA-BINDING
    8. 8.
      "Foxn4 acts synergistically with Mash1 to specify subtype identity of V2 interneurons in the spinal cord."
      Li S. , Misra K. , Matise M.P. , Xiang M.
      Proc. Natl. Acad. Sci. U.S.A.102:10688-10693(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NEUROGENESIS;DEVELOPMENTAL STAGE;TISSUE SPECIFICITY
    9. 9.
      "A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool."
      Del Barrio M.G. , Taveira-Marques R. , Muroyama Y. , Yuk D.I. , Li S. , Wines-Samuelson M. , Shen J. , Smith H.K. , Xiang M. , Rowitch D. , Richardson W.D.
      Development134:3427-3436(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NEUROGENESIS
    10. 10.
      "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
      Rardin M.J. , Newman J.C. , Held J.M. , Cusack M.P. , Sorensen D.J. , Li B. , Schilling B. , Mooney S.D. , Kahn C.R. , Verdin E. , Gibson B.W.
      Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-151;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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