Histone chaperone ASF1 (Protein name
), ASF1_CHICK from NCBI database.
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Gene name:
ASF1;
Protein name:
Histone chaperone ASF1;
Alternative:
Anti-silencing function protein 1 homolog;
Organism:
Chicken (Gallus gallus).
General Annotation
Sub Unit:
Interacts with CHAF1B, HIRA, histone H3 and histone H4.
Function:
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. May also cooperate with HIRA to promote replication-independent chromatin assembly.
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Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH CHAF1B; HIRA; HISTONE H3 AND HISTONE H4;SUBCELLULAR LOCATION;PHOSPHORYLATION;MUTAGENESIS OF 36-GLU-ASP-37