ASIC1 ELISA Kit for Chicken(Gallus gallus) | EIAab.comASIC1 ELISA Kit for Chicken(Gallus gallus)

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ASIC1 (Gene name),

Acid-sensing ion channel 1 (Protein name ), ASIC1_CHICK from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ASIC1(ACCN2);

Protein name:

Acid-sensing ion channel 1(ASIC1);

Alternative:

Amiloride-sensitive cation channel 2, neuronal;

Organism:

Chicken (Gallus gallus).

General Annotation

Sub Unit:

Homotrimer.

Function:

Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

527

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

527:

GHPAGMTYAA | NILPHHPARG | TFEDFTC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00858

UniGene:

Gga.17954

KEGG:

gga:426883

SMR:

Q1XA76

STRING:

9031.ENSGALP00000040499

Uniprot:

Q1XA76

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ELISA Kit for Chicken ASIC1

CLIA Kit for Chicken ASIC1

Polyclonal Antibody for Chicken ASIC1

Monoclonal Antibody for Chicken ASIC1

Protein for Chicken ASIC1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel."
Coric T. , Zheng D. , Gerstein M. , Canessa C.M.
J. Physiol. (Lond.)568:725-735(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
2.

"Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH."
Jasti J. , Furukawa H. , Gonzales E.B. , Gouaux E.
Nature449:316-323(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 26-463;SUBUNIT;DISULFIDE BONDS;GLYCOSYLATION AT ASN-367 AND ASN-394;FUNCTION;SUBCELLULAR LOCATION;TOPOLOGY;MUTAGENESIS OF 1-MET--SER-25 AND 464-LEU--CYS-527
3.

"Pore architecture and ion sites in acid-sensing ion channels and P2X receptors."
Gonzales E.B. , Kawate T. , Gouaux E.
Nature460:599-604(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 2-466;DISULFIDE BONDS;FUNCTION;TOPOLOGY;SUBCELLULAR LOCATION;SUBUNIT
4.

"Structure of the acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1."
Dawson R.J. , Benz J. , Stohler P. , Tetaz T. , Joseph C. , Huber S. , Schmid G. , Hugin D. , Pflimlin P. , Trube G. , Rudolph M.G. , Hennig M. , Ruf A.
Nat. Commun.3:936-936(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 26-463 IN COMPLEX WITH SPIDER VENOM PSALMOTOXIN 1;INTERACTION WITH SPIDER VENOM PSALMOTOXIN;SUBUNIT;GLYCOSYLATION AT ASN-367 AND ASN-394;MUTAGENESIS OF 1-MET--SER-25 AND 464-LEU--CYS-527
5.

"Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes."
Baconguis I. , Gouaux E.
Nature489:400-405(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 14-463;GLYCOSYLATION AT ASN-367 AND ASN-394;FUNCTION;ENZYME REGULATION;MUTAGENESIS OF 1-MET--SER-13; GLU-80 AND 464-LEU--CYS-527;DISULFIDE BOND
6.

"X-Ray structure of acid-sensing ion channel 1-snake toxin complex reveals open state of a Na(+)-selective channel."
Baconguis I. , Bohlen C.J. , Goehring A. , Julius D. , Gouaux E.
Cell156:717-729(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.07 ANGSTROMS) OF 14-463 IN COMPLEXES WITH SODIUM IONS; AMILORIDE AND THE HETERODIMERIC SNAKE VENOM NEUROTOXIN COMPOSED OF MITTX-ALPHA AND MITTX-BETA;FUNCTION;SUBCELLULAR LOCATION;SUBUNIT;ENZYME REGULATION;TOPOLOGY;DOMAIN;DISULFIDE BOND

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