Asip ELISA Kit for Mouse(Mus musculus) | EIAab.comAsip ELISA Kit for Mouse(Mus musculus)

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Asip (Gene name),

Agouti-signaling protein (Protein name ), ASIP_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Asip(a);

Protein name:

Agouti-signaling protein(ASP);

Alternative:

Agouti switch protein;Agouti coat color protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). Causes hair follicle melanocytes to synthesize phaeomelanin instead of black or brown pigment eumelanin and produces hairs with a subapical yellow band on an otherwise black or brown background when expressed during the mid-portion of hair growth.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

131

Sequence:

50:

100:

131:

PPAPACCDPC | ASCQCRFFGS | ACTCRVLNPN | C

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10090.ENSMUSP00000105319

UniGene:

Mm.315593

Pfam:

PF05039

KEGG:

mmu:50518

String:

Q03288

UniGene:

Mm.218753

SMR:

Q03288

Uniprot:

Q03288

FOR

ELISA Kit for Mouse ASP

CLIA Kit for Mouse ASP

Polyclonal Antibody for Mouse ASP

Monoclonal Antibody for Mouse ASP

Protein for Mouse ASP

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation."
Miller M.W. , Duhl D.M. , Vrieling H. , Cordes S.P. , Ollmann M.M. , Winkes B.M. , Barsh G.S.
Genes Dev.7:454-467(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Molecular characterization of the mouse agouti locus."
Bultman S.J. , Michaud E.J. , Woychik R.P.
Cell71:1195-1204(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: 129.
tissue: Mammary gland.
6.

"The embryonic lethality of homozygous lethal yellow mice (Ay/Ay) is associated with the disruption of a novel RNA-binding protein."
Michaud E.J. , Bultman S.J. , Stubbs L.J. , Woychik R.P.
Genes Dev.7:1203-1213(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-70
7.

"Neomorphic agouti mutations in obese yellow mice."
Duhl D.M. , Vrieling H. , Miller K.A. , Wolff G.L. , Barsh G.S.
Nat. Genet.8:59-65(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-16
strain: C57BL/6J.
tissue: Spleen.
8.

"Differences in dorsal and ventral pigmentation result from regional expression of the mouse agouti gene."
Vrieling H. , Duhl D.M. , Millar S.E. , Miller K.A. , Barsh G.S.
Proc. Natl. Acad. Sci. U.S.A.91:5667-5671(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-16

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