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Index > Protein center > ASPM(Gene name) > Dog
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  • ASPM (Gene name),
  • Abnormal spindle-like microcephaly-associated protein homolog (Protein name ),  ASPM_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ASPM;
    Protein name:
    Abnormal spindle-like microcephaly-associated protein homolog;
    Alternative:

    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis.
    Subcellular Location:
    Cytoplasm Nucleus The nuclear-cytoplasmic distribution could be regulated by the availability of calmodulin.
    Protein Attributes:
    Sequence length:
    3469
    Sequence:
    50:
    MATRRAGRSW | EVSPSGPRPA | AGEAAAASPP | VLSLSHFCRS | PFLCFGDVRL | 
    100:
    GGSRTLPLLL | HNPNDEAARV | EVCRAPAAQQ | GFSVSPRRFQ | LQPKEKIVIS | 
    150:
    VNWTPLKEGR | VRETVTFLVN | DVLKHQAILL | GNAEEQKKKK | RSLWGTIKKK | 
    200:
    KMSASSNNKR | ISSAQNVNKT | FCVSQKADRV | RNPLQACENL | DVNEGCSPTE | 
    250:
    NNSLILEENK | IPISPISPIF | KECNGETSLP | LSVRRSTTYI | SLHARENGDL | 
    300:
    LKVEDASILE | DFSFSEKVVN | ETSFNSTNNI | NDQTEENCKL | ILTPACSSTL | 
    350:
    NITQSQGNFL | SPDSFVKNSR | AANNELEVVT | CLSSNILMKD | NSMPLHLESK | 
    400:
    SVHENYRKIL | SPDSFINDNY | GLNQDLESEP | INPILSPNQF | VKDNMAYTCI | 
    450:
    YQQTCKLSLS | SNKNSQFSQS | QDPRTNGILP | CIPECQSSKS | PKATFEEHRA | 
    500:
    LEMKSDCYSF | TKNQPKFSAM | QDISSCSQDK | LTRRPILSAT | ITKRKSNFTR | 
    550:
    ENQKETNKPK | AKRCLNSVAG | EFEKVTDNIK | EKDGFQSCLP | VIDPVFSKPK | 
    600:
    SYKIVVTPPS | KTTLIARKRR | SEGDREDANV | RITATGHSEI | QEIKRIHFSP | 
    650:
    VESKTSVLKK | TKKMTTPISK | HFNREKLNLK | KKTDSRIYRT | PNSKTSKKTK | 
    700:
    PIVAVAQSTL | TFIKPLKTDI | PRHPMPFAAK | NMFYDERWKE | KQEQGFTWWL | 
    750:
    NFILTPDDFT | VKTNISEVNA | ATLLLGVESQ | HKISVPRAPT | KDEMSLRAYT | 
    800:
    ARCRLNRLRR | AACRLFTSEK | MVKAIKKLEI | EIEARRLIVR | RDRHLWKDVG | 
    850:
    ERQKVLNWLL | SYNPLWLRIG | LETVFGELLS | LEDNSDVTGL | AVFILNRLLW | 
    900:
    NPDIAAEYRH | PTVPHLYRDG | HEEALSKFTL | KKLLLLVCFL | DYAKISKLID | 
    950:
    HDPCLFCKDA | EFKTSKDILL | AFSRDFLSGE | GDLSRHLSLL | GLPVNHVQTP | 
    1000:
    FDEFDFAVTN | LAVDLQCGVR | LVRIMELLTR | DWNLSKKLRM | PAISRLQKMH | 
    1050:
    NVDIVLQILR | SQGIQLNDEH | GNAILSKDIV | DRHREKTLAL | LWKIAFAFQV | 
    1100:
    DISLNLDQLK | EEIDFLKHTQ | SMKKMSAQSC | HSDVIINKKK | DNRNSGSFEQ | 
    1150:
    YSESIKLLME | WVNAVCAFYN | KKVENFTVSF | SDGRVLCYLI | HHYHPYYVPF | 
    1200:
    DAICQRTTQT | IECTQTGSVV | LNSSSESDGS | SLDLSLKAFD | HENTSELYKE | 
    1250:
    LLENEKKNFQ | LVRSAVRDLG | GIPAMINHSD | MSNTIPDEKV | VITYLSFLCS | 
    1300:
    RLLDLCKETR | AARLIQTTWR | KYKLKTDMKR | HQEQDKAARI | IQSAIINFLT | 
    1350:
    KRRLKKEISA | ALAIQKYWRR | FLAQRKLLML | KKEKLEKVQN | ESASIIQRYW | 
    1400:
    RRYSTRKQFL | KLRYYSIILQ | SRIRMIIAVT | SYKRYLWATV | TIQRHWRASL | 
    1450:
    RRKHDQQRYK | MLKSSCLIIQ | SMFRRWKRRK | MQLQIKATRV | LQRAFREWHV | 
    1500:
    RKRAKEEKSA | IVIQSWYRMH | KELRKYVQIR | SCVVIIQTRF | RCLQAQKLYK | 
    1550:
    RKKEAILTIQ | KYYKAYLKGK | MERTNYLQKR | AAAIRLQTAF | RRMKARNLYR | 
    1600:
    QSRAACVLQS | YWRMRQDRFR | FLNLKKITTK | LQAQVRKHQQ | LQKYRKIKKA | 
    1650:
    ALVIQIHFRA | YVSAKKVLAS | YQKTRSAVLV | LQSAYRGMQA | RKKFIHILTS | 
    1700:
    IIKIQSCYRA | YISRKRFLRL | KNATVKLQSI | VKMRQTRKRY | LHWRAASLFI | 
    1750:
    QRWYRSAKLA | ALKRHQYVQM | RESCIKLQAF | VRGHLVRKQI | RLQRQAAISL | 
    1800:
    QSYFRMRKKR | QYYLEIYKAT | LVIQNYYRAY | KAQVNQRKNF | LQVKRAVTCL | 
    1850:
    QAAYRGYKVR | QLIKQQSIAA | LKIQTAFRGY | RERKKYQYVL | QSTIKIQRWY | 
    1900:
    RTCRTVRDVR | TQFLKTRAAV | ISLQCAFRGW | KVRKQIRRER | QAAVRIQSAF | 
    1950:
    RMAKAQKQFK | LLKTAALVIQ | QHLRAWTAGK | RQRMEYIELR | EAALRLQSTW | 
    2000:
    KGKRVRRQVQ | KQHKCAVIIQ | SNYRMYVQQK | KWKIMKKAAR | LIQMYYRAYS | 
    2050:
    IGRKQRQLYL | KTKAAAVVLQ | SAYRSMKVRK | KIKECNRAAV | TIQSTYRAYK | 
    2100:
    TKKNYTNCRA | SAIIIQRWYR | GTKIANHQRK | EYLNLKKTAV | KIQAIYRGIR | 
    2150:
    VRRHNRHLHM | AATVIQAMFK | MHQAKMRYHK | MRTAAVIIQV | RYRAYREGKI | 
    2200:
    QRAKYLTIMK | AITVLQASFR | GTRVRQTLRK | MQSAATLIQS | YYRRHRQQAY | 
    2250:
    FTKLKKVTRT | IQQRYRAVKE | RNTQLQRYNK | LRHSIICIQA | GFRGMKARRH | 
    2300:
    LKSMHLAATL | IQRRFRTLRM | RRRFLHLRKT | AIWIQRKYRA | TVCAKHYFQH | 
    2350:
    FVRVQKAVIK | IQSSYRGWMV | RKKMQEVHRA | ATAIQAAFRM | HRANVKYQAL | 
    2400:
    KHASVVIQQQ | FRASRAAKLQ | RQCYLQQRHS | ALILQAAFRG | MKARGHLKNM | 
    2450:
    HSSATLIQST | FRSLVVRKRF | ISLKRATVFV | QRKYRATICA | RHHLHQFLKL | 
    2500:
    KKAVITIQSS | YRRLVAKKKL | QEMHRAAVLI | QATYRMHRTY | VTFQTWKHAS | 
    2550:
    ILIQQHYRTY | RAAKLQRENS | VPQRRSALII | QAVYKGMKAR | QLLREKHRAA | 
    2600:
    IIIQSTYRMY | RQYLFYQKIQ | WATKVIQEKY | RANKKKALQH | SALRNAAAAC | 
    2650:
    TEADFQDMIL | RKPTQEQHQA | ATIIQKHFKA | SKVRKHYLHL | RANVIFVQRR | 
    2700:
    YRALTAVRTQ | AVVCTQSSYR | SCKVQEDMQH | RHLAATRIQS | FYRMHRAKLD | 
    2750:
    YQAKKTAVAV | IQNYFRSYIR | VKVEREKFLA | VQKSVRIIQA | AFRGMKVRER | 
    2800:
    LKSLSEVNMV | ASAKQSAFYS | CRTEAQCAAV | HGSALRTQKW | HGASLVTCSQ | 
    2850:
    EAEYPQREAL | VATQRAFCEM | VTRKLETQKC | AALRIQYFLQ | MAVCRRRFVQ | 
    2900:
    QKRAAVTLQQ | YFRTWQTRRQ | FLLYRKAAVV | LQNHHRAFLS | TKHQRQVYLQ | 
    2950:
    IRSSIIMIQA | RTRGFIQKRR | FQKIKDSTIK | IQAVWRSYKA | RKYLHQVKAA | 
    3000:
    CKIQAWYRYW | KARKDYLAVL | KAVKIIQGCF | YTKLERRRFL | NVRASTIIIQ | 
    3050:
    RKWRAILSGR | IACEHFLMIK | RHQAACLIQA | NFRRYKGRQV | FLRQKSAALT | 
    3100:
    IQRYIRARKA | GKCQRIKYVE | LKKSTVVLQA | LVRGWLVRKR | ILEQRTKIRL | 
    3150:
    LHFTAAAYYH | LSALKIQRAY | KRHMAMKNAN | KQVNAVICIQ | RWFRTRLQQK | 
    3200:
    RFAQKYPSIL | TSQHEVPECM | SQQNRAASVI | QKAVRRFLLR | KKQEKFNNAI | 
    3250:
    SRIQSLWRGY | SWRKKNDCTK | IKAIRLSLQL | VNREIREENK | LYKRTALALH | 
    3300:
    YLLTYKHLSA | ILEALKHLEV | VTRLSPLCCE | NMAQSGAVSK | IFVLIRSCNR | 
    3350:
    SIPCMEVIRY | AVQVLLNVAK | YEKTTAAVSD | VENCIDTLLD | LLQMYREKPG | 
    3400:
    DKVADKGGSI | FTKTCCLLAV | LLKTTNRASS | VRSKSKVVDR | IYSLYKLTAR | 
    3450:
    KHKMNTERTL | YKQKMNSSIS | TPFIPETPVR | TRIVSRLKPD | WVLRRDNMEE | 
    3469:
    ITNPLQAIQM | VMDTLGIPY
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Dog Abnormal spindle-like microcephaly-associated protein homolog
    ELISA Kit for Dog Abnormal spindle-like microcephaly-associated protein homolog
    ELISA Kit for Dog Abnormal spindle-like microcephaly-associated protein homolog
    ELISA Kit for Dog Abnormal spindle-like microcephaly-associated protein homolog
    CLIA Kit for Dog Abnormal spindle-like microcephaly-associated protein homolog
    CLIA Kit for Dog Abnormal spindle-like microcephaly-associated protein homolog
    CLIA Kit for Dog Abnormal spindle-like microcephaly-associated protein homolog
    CLIA Kit for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Polyclonal Antibody for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Polyclonal Antibody for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Polyclonal Antibody for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Polyclonal Antibody for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Monoclonal Antibody for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Monoclonal Antibody for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Monoclonal Antibody for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Monoclonal Antibody for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Protein for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Protein for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Protein for Dog Abnormal spindle-like microcephaly-associated protein homolog
    Protein for Dog Abnormal spindle-like microcephaly-associated protein homolog

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    References
    1. 1.
      "Genome sequence, comparative analysis and haplotype structure of the domestic dog."
      Lindblad-Toh K. , Wade C.M. , Mikkelsen T.S. , Karlsson E.K. , Jaffe D.B. , Kamal M. , Clamp M. , Chang J.L. , Kulbokas E.J. III , Zody M.C. , Mauceli E. , Xie X. , Breen M. , Wayne R.K. , Ostrander E.A. , Ponting C.P. , Galibert F. , Smith D.R. , more...
      Nature438:803-819(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Boxer.
    2. 2.
      "Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans."
      Evans P.D. , Anderson J.R. , Vallender E.J. , Gilbert S.L. , Malcom C.M. , Dorus S. , Lahn B.T.
      Hum. Mol. Genet.13:489-494(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-3452
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