Gene name:
PPP1R13B (ASPP1;KIAA0771) ;
Protein name:
Apoptosis-stimulating of p53 protein 1 ;
Alternative:
Protein phosphatase 1 regulatory subunit 13B ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with TP53.
Function:
Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.
Subcellular Location:
Cytoplasm
Nucleus
Predominantly cytoplasmic. Some fraction is nuclear.
Protein Attributes:
50:
MMPMILTVFL | SNNEQILTEV | PITPETTCRD | VVEFCKEPGE | GSCHLAEVWR |
100:
GNERPIPFDH | MMYEHLQKWG | PRREEVKFFL | RHEDSPTENS | EQGGRQTQEQ |
150:
RTQRNVINVP | GEKRTENGVG | NPRVELTLSE | LQDMAARQQQ | QIENQQQMLV |
200:
AKEQRLHFLK | QQERRQQQSI | SENEKLQKLK | ERVEAQENKL | KKIRAMRGQV |
250:
DYSKIMNGNL | SAEIERFSAM | FQEKKQEVQT | AILRVDQLSQ | QLEDLKKGKL |
300:
NGFQSYNGKL | TGPAAVELKR | LYQELQIRNQ | LNQEQNSKLQ | QQKELLNKRN |
350:
MEVAMMDKRI | SELRERLYGK | KIQLNRVNGT | SSPQSPLSTS | GRVAAVGPYI |
400:
QVPSAGSFPV | LGDPIKPQSL | SIASNAAHGR | SKSANDGNWP | TLKQNSSSSV |
450:
KPVQVAGADW | KDPSVEGSVK | QGTVSSQPVP | FSALGPTEKP | GIEIGKVPPP |
500:
IPGVGKQLPP | SYGTYPSPTP | LGPGSTSSLE | RRKEGSLPRP | SAGLPSRQRP |
550:
TLLPATGSTP | QPGSSQQIQQ | RISVPPSPTY | PPAGPPAFPA | GDSKPELPLT |
600:
VAIRPFLADK | GSRPQSPRKG | PQTVNSSSIY | SMYLQQATPP | KNYQPAAHSA |
650:
LNKSVKAVYG | KPVLPSGSTS | PSPLPFLHGS | LSTGTPQPQP | PSESTEKEPE |
700:
QDGPAAPADG | STVESLPRPL | SPTKLTPIVH | SPLRYQSDAD | LEALRRKLAN |
750:
APRPLKKRSS | ITEPEGPGGP | NIQKLLYQRF | NTLAGGMEGT | PFYQPSPSQD |
800:
FMGTLADVDN | GNTNANGNLE | ELPPAQPTAP | LPAEPAPSSD | ANDNELPSPE |
850:
PEELICPQTT | HQTAEPAEDN | NNNVATVPTT | EQIPSPVAEA | PSPGEEQVPP |
900:
APLPPASHPP | ATSTNKRTNL | KKPNSERTGH | GLRVRFNPLA | LLLDASLEGE |
950:
FDLVQRIIYE | VEDPSKPNDE | GITPLHNAVC | AGHHHIVKFL | LDFGVNVNAA |
1000:
DSDGWTPLHC | AASCNSVHLC | KQLVESGAAI | FASTISDIET | AADKCEEMEE |
1050:
GYIQCSQFLY | GVQEKLGVMN | KGVAYALWDY | EAQNSDELSF | HEGDALTILR |
1090:
RKDESETEWW | WARLGDREGY | VPKNLLGLYP | RIKPRQRTLA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Apoptosis-stimulating of p53 protein 1
ELISA Kit for Human Apoptosis-stimulating of p53 protein 1
CLIA Kit for Human Apoptosis-stimulating of p53 protein 1
CLIA Kit for Human Apoptosis-stimulating of p53 protein 1
Polyclonal Antibody for Human Apoptosis-stimulating of p53 protein 1
Polyclonal Antibody for Human Apoptosis-stimulating of p53 protein 1
Monoclonal Antibody for Human Apoptosis-stimulating of p53 protein 1
Monoclonal Antibody for Human Apoptosis-stimulating of p53 protein 1
Protein for Human Apoptosis-stimulating of p53 protein 1
Protein for Human Apoptosis-stimulating of p53 protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH TP53
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 143-1090
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-681;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-332 AND SER-335;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cervix carcinoma .