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Index > Protein center > ASUN(Gene name) > Human
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  • ASUN (Gene name),
  • Protein asunder homolog (Protein name ),  ASUN_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ASUN(C12orf11;GCT1);
    Protein name:
    Protein asunder homolog;
    Alternative:
    Germ cell tumor 1;Cell cycle regulator Mat89Bb homolog;Sarcoma antigen NY-SAR-95;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with PAFAH1B1; this interaction may be required for proper recruitment of dynein complexes to the nuclear envelope at prophase.
    Function:
    Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    706
    Sequence:
    50:
    MKIFSESHKT | VFVVDHCPYM | AESCRQHVEF | DMLVKNRTQG | IIPLAPISKS | 
    100:
    LWTCSVESSM | EYCRIMYDIF | PFKKLVNFIV | SDSGAHVLNS | WTQEDQNLQE | 
    150:
    LMAALAAVGP | PNPRADPECC | SILHGLVAAV | ETLCKITEYQ | HEARTLLMEN | 
    200:
    AERVGNRGRI | ICITNAKSDS | HVRMLEDCVQ | ETIHEHNKLA | ANSDHLMQIQ | 
    250:
    KCELVLIHTY | PVGEDSLVSD | RSKKELSPVL | TSEVHSVRAG | RHLATKLNIL | 
    300:
    VQQHFDLAST | TITNIPMKEE | QHANTSANYD | VELLHHKDAH | VDFLKSGDSH | 
    350:
    LGGGSREGSF | KETITLKWCT | PRTNNIELHY | CTGAYRISPV | DVNSRPSSCL | 
    400:
    TNFLLNGRSV | LLEQPRKSGS | KVISHMLSSH | GGEIFLHVLS | SSRSILEDPP | 
    450:
    SISEGCGGRV | TDYRITDFGE | FMRENRLTPF | LDPRYKIDGS | LEVPLERAKD | 
    500:
    QLEKHTRYWP | MIISQTTIFN | MQAVVPLASV | IVKESLTEED | VLNCQKTIYN | 
    550:
    LVDMERKNDP | LPISTVGTRG | KGPKRDEQYR | IMWNELETLV | RAHINNSEKH | 
    600:
    QRVLECLMAC | RSKPPEEEER | KKRGRKREDK | EDKSEKAVKD | YEQEKSWQDS | 
    650:
    ERLKGILERG | KEELAEAEII | KDSPDSPEPP | NKKPLVEMDE | TPQVEKSKGP | 
    700:
    VSLLSLWSNR | INTANSRKHQ | EFAGRLNSVN | NRAELYQHLK | EENGMETTEN | 
    706:
    GKASRQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    KEGG:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein asunder homolog
    ELISA Kit for Human Protein asunder homolog
    CLIA Kit for Human Protein asunder homolog
    CLIA Kit for Human Protein asunder homolog
    Polyclonal Antibody for Human Protein asunder homolog
    Polyclonal Antibody for Human Protein asunder homolog
    Monoclonal Antibody for Human Protein asunder homolog
    Monoclonal Antibody for Human Protein asunder homolog
    Protein for Human Protein asunder homolog
    Protein for Human Protein asunder homolog

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
    2. 2.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Eye.
      tissue: Lymph.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 269-513 (ISOFORM 1)
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 568-706 (ISOFORM 1)
      tissue: Testis.
    6. 6.
      "Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes."
      Bourdon V. , Naef F. , Rao P.H. , Reuter V. , Mok S.C. , Bosl G.J. , Koul S. , Murty V.V. , Kucherlapati R.S. , Chaganti R.S.
      Cancer Res.62:6218-6223(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    7. 7.
      "Drosophila genome-scale screen for PAN GU kinase substrates identifies Mat89Bb as a cell cycle regulator."
      Lee L.A. , Lee E. , Anderson M.A. , Vardy L. , Tahinci E. , Ali S.M. , Kashevsky H. , Benasutti M. , Kirschner M.W. , Orr-Weaver T.L.
      Dev. Cell8:435-442(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    8. 8.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-626;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-626;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-626;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry."
      Jodoin J.N. , Shboul M. , Sitaram P. , Zein-Sabatto H. , Reversade B. , Lee E. , Lee L.A.
      Mol. Biol. Cell23:4713-4724(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PAFAH1B1;SUBCELLULAR LOCATION
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] PRO-227
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