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Index > Protein center > Asxl1(Gene name) > Mouse
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  • Asxl1 (Gene name),
  • Putative Polycomb group protein ASXL1 (Protein name ),  ASXL1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Asxl1(Kiaa0978);
    Protein name:
    Putative Polycomb group protein ASXL1;
    Alternative:
    Additional sex combs-like protein 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the PR-DUB complex, at least composed of BAP1 and ASXL1.
    Function:
    Probable Polycomb group (PcG) protein. Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1).
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    1514
    Sequence:
    50:
    MKDKQKRKKE | RTWAEAARLV | LENYSDAPMT | PKQILQVIEA | EGLKEMRSGT | 
    100:
    SPLACLNAML | HSNSRGGEGL | FYKLPGRISL | FTLKKDAVQW | SRNAATVDGD | 
    150:
    EPEDSADVES | CGSNEASTVS | GENDVSLDET | SSNASCSTES | QSRPLSNPRD | 
    200:
    SHRASSQANK | QKKRTGVMLP | RVVLTPLKVN | GAHVEPASGF | SGRHADGESG | 
    250:
    SPSSSSSGSL | ALGNSAIRGQ | AEVTRDPAPL | LRGFRKPATG | QMKRNRGEEV | 
    300:
    DFETPGSILV | NTNLRALINS | RTFHALPLHF | QQQLLLLLPE | VDRQVGTDGL | 
    350:
    LRLSGSALNN | EFFTHAAQSW | RERLADGEFT | HEMQVRLRQE | MEKEKKVEQW | 
    400:
    KEKFFEDYYG | QKLGLTKEES | LQQKEVQEEA | KVKSGLCVSG | ESVRPQRGPN | 
    450:
    TRQRDGHFKK | RSRPDLRTRS | RRNIYKKQEP | EQAGVAKDAS | AAPDVSLSKD | 
    500:
    TKTDLAGVNS | TPGPDVSSAT | SGQEGPKCPS | EPVASQIQAE | RDNLACASAS | 
    550:
    PDRIPTLPQD | TVDQETKDQK | RKSFEQEASA | SFPEKKPRLE | DRQSFRNTIE | 
    600:
    SVHTEKPQPT | KEEPKVPPIR | IQLSRIKPPW | VAKGRPTYQI | CPRIVPITES | 
    650:
    SCRGWTGART | LADIKARALQ | ARGARGYHCN | RETATTAIGG | GGGPGGGGSG | 
    700:
    AIDEGGGRDS | SSGDGSEACG | HPEPRGAPST | SGESASDLQR | TQLLPPCPLN | 
    750:
    GEHTPAEAAM | PRARREDSAS | LRKEESCLLK | RVPGVLTSGL | EDASQPPIAP | 
    800:
    TGDQPCQALP | PLSSQTPVAE | MLTEQPKLLL | DDRTECESSR | EDQGPTIPSE | 
    850:
    SSSGRFPLGD | LLGGGSDQAF | DNMKEPVSMT | PTFISELSLA | NYLQDRPDDD | 
    900:
    GLGLGATGLL | IRESSRQEAL | TEAFASGSPT | SWVPILSNYE | VIKTSDPESR | 
    950:
    ENIPCPEPQD | EKEWERAVPL | IAATESVPQP | ESCISHWTPP | PAAVGSTGSD | 
    1000:
    SEQVDLERLE | MNGISEAPSP | HSESTDTASD | SEGHLSEDSS | EVDASEVTVV | 
    1050:
    KGSLGGDEKQ | DWDPSASLSK | VNNDLSVLTR | TGGVAASQSW | VSRVCSVPHK | 
    1100:
    IPDSLLLSST | ECQPRSVCPL | RPGSSVEVTN | PLVMHLLHGN | LPLEKVLPPG | 
    1150:
    HRSSRLESSQ | LPLREQSQDR | GTLQGTGENN | RLAARINPGS | AQTLKESILA | 
    1200:
    QSYGASAGLV | RAMASKAPAM | SQKIAKMVTS | LDSQHPETEL | TPSSGNLEEI | 
    1250:
    DSKEHLSSFL | CEEQKEGHSL | SQGSDPGAAP | GQCLGDHTTS | KVPCFSSTNV | 
    1300:
    SLSFGSEQTD | GTLSDQNNAG | GHEKKLFGPG | NTVTTLQCPR | SEEQTPLPAE | 
    1350:
    VPPVFPSRKI | EPSKNSVSGG | VQTTRENRMP | KPPPVSADSI | KTEQTFLRDP | 
    1400:
    IKADAENRKA | AGYSSLELVG | HLQGMPFVVD | LPFWKLPREP | GKGFSQPLEP | 
    1450:
    SSIPSQLNIK | QALYGKLSKL | QLSPTSFNYS | SSSATFPKGL | AGGVVQLSHK | 
    1500:
    ASFGTGHTAS | LSLQMFADSS | AVESISLQCA | CSLKAMIMCQ | GCGAFCHDDC | 
    1514:
    IGPSKLCVLC | LVVR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Putative Polycomb group protein ASXL1
    ELISA Kit for Mouse Putative Polycomb group protein ASXL1
    CLIA Kit for Mouse Putative Polycomb group protein ASXL1
    CLIA Kit for Mouse Putative Polycomb group protein ASXL1
    Polyclonal Antibody for Mouse Putative Polycomb group protein ASXL1
    Polyclonal Antibody for Mouse Putative Polycomb group protein ASXL1
    Monoclonal Antibody for Mouse Putative Polycomb group protein ASXL1
    Monoclonal Antibody for Mouse Putative Polycomb group protein ASXL1
    Protein for Mouse Putative Polycomb group protein ASXL1
    Protein for Mouse Putative Polycomb group protein ASXL1

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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Aizawa H. , Yuasa S. , Nakajima D. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    2. 2.
      "Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor."
      Cho Y.S. , Kim E.J. , Park U.H. , Sin H.S. , Um S.J.
      J. Biol. Chem.281:17588-17598(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH RARA AND RXRA
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    4. 4.
      "ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1."
      Lee S.W. , Cho Y.S. , Na J.M. , Park U.H. , Kang M. , Kim E.J. , Um S.J.
      J. Biol. Chem.285:18-29(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH KDM1A; CBX1; CBX3 AND CBX5;MUTAGENESIS OF PRO-170; VAL-172 AND LEU-174
    5. 5.
      "Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}."
      Park U.H. , Yoon S.K. , Park T. , Kim E.J. , Um S.J.
      J. Biol. Chem.286:1354-1363(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PPARA AND PPARG
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