Gene name:
ASXL2 (ASXH2;KIAA1685) ;
Protein name:
Putative Polycomb group protein ASXL2 ;
Alternative:
Additional sex combs-like protein 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MREKGRRKKG | RTWAEAAKTV | LEKYPNTPMS | HKEILQVIQR | EGLKEIRSGT |
100:
SPLACLNAML | HTNSRGEEGI | FYKVPGRMGV | YTLKKDVPDG | VKELSEGSEE |
150:
SSDGQSDSQS | SENSSSSSDG | GSNKEGKKSR | WKRKVSSSSP | QSGCPSPTIP |
200:
AGKVISPSQK | HSKKALKQAL | KQQQQKKQQQ | QCRPSISISS | NQHLSLKTVK |
250:
AASDSVPAKP | ATWEGKQSDG | QTGSPQNSNS | SFSSSVKVEN | TLLGLGKKSF |
300:
QRSERLHTRQ | MKRTKCADID | VETPDSILVN | TNLRALINKH | TFSVLPGDCQ |
350:
QRLLLLLPEV | DRQVGPDGLM | KLNGSALNNE | FFTSAAQGWK | ERLSEGEFTP |
400:
EMQVRIRQEI | EKEKKVEPWK | EQFFESYYGQ | SSGLSLEDSK | KLTASPSDPK |
450:
VKKTPAEQPK | SMPVSEASLI | RIVPVVSQSE | CKEEALQMSS | PGRKEECESQ |
500:
GEVQPNFSTS | SEPLLSSALN | THELSSILPI | KCPKDEDLLE | QKPVTSAEQE |
550:
SEKNHLTTAS | NYNKSESQES | LVTSPSKPKS | PGVEKPIVKP | TAGAGPQETN |
600:
MKEPLATLVD | QSPESLKRKS | SLTQEEAPVS | WEKRPRVTEN | RQHQQPFQVS |
650:
PQPFLNRGDR | IQVRKVPPLK | IPVSRISPMP | FHPSQVSPRA | RFPVSITSPN |
700:
RTGARTLADI | KAKAQLVKAQ | RAAAAAAAAA | AAAASVGGTI | PGPGPGGGQG |
750:
PGEGGEGQTA | RGGSPGSDRV | SETGKGPTLE | LAGTGSRGGT | RELLPCGPET |
800:
QPQSETKTTP | SQAQPHSVSG | AQLQQTPPVP | PTPAVSGACT | SVPSPAHIEK |
850:
LDNEKLNPTR | ATATVASVSH | PQGPSSCRQE | KAPSPTGPAL | ISGASPVHCA |
900:
ADGTVELKAG | PSKNIPNPSA | SSKTDASVPV | AVTPSPLTSL | LTTATLEKLP |
950:
VPQVSATTAP | AGSAPPSSTL | PAASSLKTPG | TSLNMNGPTL | RPTSSIPANN |
1000:
PLVTQLLQGK | DVPMEQILPK | PLTKVEMKTV | PLTAKEERGM | GALIATNTTE |
1050:
NSTREEVNER | QSHPATQQQL | GKTLQSKQLP | QVPRPLQLFS | AKELRDSSID |
1100:
THQYHEGLSK | ATQDQILQTL | IQRVRRQNLL | SVVPPSQFNF | AHSGFQLEDI |
1150:
STSQRFMLGF | AGRRTSKPAM | AGHYLLNIST | YGRGSESFRR | THSVNPEDRF |
1200:
CLSSPTEALK | MGYTDCKNAT | GESSSSKEDD | TDEESTGDEQ | ESVTVKEEPQ |
1250:
VSQSAGKGDT | SSGPHSRETL | STSDCLASKN | VKAEIPLNEQ | TTLSKENYLF |
1300:
TRGQTFDEKT | LARDLIQAAQ | KQMAHAVRGK | AIRSSPELFS | STVLPLPADS |
1350:
PTHQPLLLPP | LQTPKLYGSP | TQIGPSYRGM | INVSTSSDMD | HNSAVPGSQV |
1400:
SSNVGDVMSF | SVTVTTIPAS | QAMNPSSHGQ | TIPVQAFSEE | NSIEGTPSKC |
1435:
YCRLKAMIMC | KGCGAFCHDD | CIGPSKLCVS | CLVVR
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Chicken
Human
ELISA Kit for Human Putative Polycomb group protein ASXL2
ELISA Kit for Human Putative Polycomb group protein ASXL2
ELISA Kit for Human Putative Polycomb group protein ASXL2
CLIA Kit for Human Putative Polycomb group protein ASXL2
CLIA Kit for Human Putative Polycomb group protein ASXL2
CLIA Kit for Human Putative Polycomb group protein ASXL2
Polyclonal Antibody for Human Putative Polycomb group protein ASXL2
Polyclonal Antibody for Human Putative Polycomb group protein ASXL2
Polyclonal Antibody for Human Putative Polycomb group protein ASXL2
Monoclonal Antibody for Human Putative Polycomb group protein ASXL2
Monoclonal Antibody for Human Putative Polycomb group protein ASXL2
Monoclonal Antibody for Human Putative Polycomb group protein ASXL2
Protein for Human Putative Polycomb group protein ASXL2
Protein for Human Putative Polycomb group protein ASXL2
Protein for Human Putative Polycomb group protein ASXL2
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 890-1435 (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic kidney .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-146;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Leukemic T-cell .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH PPARA AND PPARG