Protein name:
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 ;
Alternative:
Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein ;
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.
Function:
Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
Subcellular Location:
Cytoplasm
Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs.
Protein Attributes:
50:
MATGSLRGLA | VAGGGESSDS | EDDGWEIGYL | DRPPQKLKGP | LPIEEKNETF |
100:
KKALTTGDTS | LVKELLDSGI | SVDSSFRYGW | TPLMYAASVA | NVELVRVLLD |
150:
RGANASFDKD | KQTILITACS | ARGSEEQILK | CVELLLSRNA | DPNVACRRLM |
200:
TPIMYAARDG | HPQVVALLVA | HGAEVNIQDE | NGYTALTWAA | RQGHKSVVLK |
250:
LLELGANKTL | QTKDGKTPSE | IAKRNKHLEI | FNLLSLTLNP | LEGKLQQLTK |
300:
EETICKLLTT | DSDKEKDHIF | SSYTAFGDLE | IFLHGLGLEH | MTDLLKERDI |
350:
TLRHLLTMRK | DEFTQNGITS | KDQQKILAAL | KELEVEEIKF | GELPEVAKLE |
400:
ISGDEFLNFL | LKLNKQCGHL | ITAVQNIITE | LPVNSHKIVL | EWASPRNFTS |
450:
VCEELVSNVE | DLNEEVCKLK | DLIQKLQNER | ENDPTHIPLM | EEVSTWNSKI |
475:
LKRTAVTVCG | FGFLLFICKL | TFQRK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rabbit
Human
Bovine
Mouse
ELISA Kit for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
ELISA Kit for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
ELISA Kit for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
ELISA Kit for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
CLIA Kit for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
CLIA Kit for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
CLIA Kit for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
CLIA Kit for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Polyclonal Antibody for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Polyclonal Antibody for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Polyclonal Antibody for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Polyclonal Antibody for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Monoclonal Antibody for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Monoclonal Antibody for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Monoclonal Antibody for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Monoclonal Antibody for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Protein for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Protein for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Protein for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Protein for Rabbit Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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more...
Submitted (2006-09) to the EMBL/GenBank/DDBJ databases
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]