Gene name:
Atp2b2 (Pmca2) ;
Protein name:
Plasma membrane calcium-transporting ATPase 2 (PMCA2) ;
Alternative:
Plasma membrane calcium pump isoform 2 ;Plasma membrane calcium ATPase isoform 2 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. Plays a role in maintaining balance and hearing.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MGDMTNSDFY | SKNQRNESSH | GGEFGCTMEE | LRSLMELRGT | EAVVKIKETY |
100:
GDTEAICRRL | KTSPVEGLPG | TAPDLEKRKQ | IFGQNFIPPK | KPKTFLQLVW |
150:
EALQDVTLII | LEIAAIISLG | LSFYHPPGES | NEGCATAQGG | AEDEGEAEAG |
200:
WIEGAAILLS | VICVVLVTAF | NDWSKEKQFR | GLQSRIEQEQ | KFTVVRAGQV |
250:
VQIPVAEIVV | GDIAQIKYGD | LLPADGLFIQ | GNDLKIDESS | LTGESDQVRK |
300:
SVDKDPMLLS | GTHVMEGSGR | MVVTAVGVNS | QTGIIFTLLG | AGGEEEEKKD |
350:
KKAKQQDGAA | AMEMQPLKSA | EGGDADDKKK | ANMHKKEKSV | LQGKLTKLAV |
400:
QIGKAGLVMS | AITVIILVLY | FTVDTFVVNK | KPWLTECTPV | YVQYFVKFFI |
450:
IGVTVLVVAV | PEGLPLAVTI | SLAYSVKKMM | KDNNLVRHLD | ACETMGNATA |
500:
ICSDKTGTLT | TNRMTVVQAY | VGDVHYKEIP | DPSSINAKTL | ELLVNAIAIN |
550:
SAYTTKILPP | EKEGALPRQV | GNKTECGLLG | FVLDLRQDYE | PVRSQMPEEK |
600:
LYKVYTFNSV | RKSMSTVIKM | PDESFRMYSK | GASEIVLKKC | CKILSGAGEA |
650:
RVFRPRDRDE | MVKKVIEPMA | CDGLRTICVA | YRDFPSSPEP | DWDNENDILN |
700:
ELTCICVVGI | EDPVRPEVPE | AIRKCQRAGI | TVRMVTGDNI | NTARAIAIKC |
750:
GIIHPGEDFL | CLEGKEFNRR | IRNEKGEIEQ | ERIDKIWPKL | RVLARSSPTD |
800:
KHTLVKGIID | STHTEQRQVV | AVTGDGTNDG | PALKKADVGF | AMGIAGTDVA |
850:
KEASDIILTD | DNFSSIVKAV | MWGRNVYDSI | SKFLQFQLTV | NVVAVIVAFT |
900:
GACITQDSPL | KAVQMLWVNL | IMDTFASLAL | ATEPPTETLL | LRKPYGRNKP |
950:
LISRTMMKNI | LGHAVYQLTL | IFTLLFVGEK | MFQIDSGRNA | PLHSPPSEHY |
1000:
TIIFNTFVMM | QLFNEINARK | IHGERNVFDG | IFRNPIFCTI | VLGTFAIQIV |
1050:
IVQFGGKPFS | CSPLQLDQWM | WCIFIGLGEL | VWGQVIATIP | TSRLKFLKEA |
1100:
GRLTQKEEIP | EEELNEDVEE | IDHAERELRR | GQILWFRGLN | RIQTQIRVVK |
1150:
AFRSSLYEGL | EKPESRTSIH | NFMAHPEFRI | EDSQPHIPLI | DDTDLEEDAA |
1198:
LKQNSSPPSS | LNKNNSAIDS | GINLTTDTSK | SATSSSPGSP | IHSLETSL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Mouse PMCA2
ELISA Kit for Mouse PMCA2
ELISA Kit for Mouse PMCA2
Polyclonal Antibody for Mouse PMCA2
Polyclonal Antibody for Mouse PMCA2
Polyclonal Antibody for Mouse PMCA2
Monoclonal Antibody for Mouse PMCA2
Monoclonal Antibody for Mouse PMCA2
Monoclonal Antibody for Mouse PMCA2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;VARIANT DFW SER-243
strain :
C3H/HeJ .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT LYS-412
strain :
BALB/C WMS .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 16-32; 46-58; 62-77; 80-90; 197-249; 251-270; 305-318; 438-455; 464-477; 489-506; 537-543; 554-561; 570-576; 581-588; 593-601; 626-632; 684-694; 757-767; 785-818; 825-832; 931-938; 976-983; 1104-1116; 1130-1152 AND 1164-1180
strain :
C57BL/6 .
tissue :
Brain .
4.
"Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2."
Kozel P.J.
,
Friedman R.A.
,
Erway L.C.
,
Yamoah E.N.
,
Liu L.H.
,
Riddle T.
,
Duffy J.J.
,
Doetschman T.
,
Miller M.L.
,
Cardell E.L.
,
Shull G.E.
J. Biol. Chem.273:18693-18696(1998)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY