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Index > Protein center > Atp2b2(Gene name) > Mouse
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  • Atp2b2 (Gene name),
  • Plasma membrane calcium-transporting ATPase 2 (Protein name ),  AT2B2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Atp2b2(Pmca2);
    Protein name:
    Plasma membrane calcium-transporting ATPase 2(PMCA2);
    Alternative:
    Plasma membrane calcium pump isoform 2;Plasma membrane calcium ATPase isoform 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. Plays a role in maintaining balance and hearing.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1198
    Sequence:
    50:
    MGDMTNSDFY | SKNQRNESSH | GGEFGCTMEE | LRSLMELRGT | EAVVKIKETY | 
    100:
    GDTEAICRRL | KTSPVEGLPG | TAPDLEKRKQ | IFGQNFIPPK | KPKTFLQLVW | 
    150:
    EALQDVTLII | LEIAAIISLG | LSFYHPPGES | NEGCATAQGG | AEDEGEAEAG | 
    200:
    WIEGAAILLS | VICVVLVTAF | NDWSKEKQFR | GLQSRIEQEQ | KFTVVRAGQV | 
    250:
    VQIPVAEIVV | GDIAQIKYGD | LLPADGLFIQ | GNDLKIDESS | LTGESDQVRK | 
    300:
    SVDKDPMLLS | GTHVMEGSGR | MVVTAVGVNS | QTGIIFTLLG | AGGEEEEKKD | 
    350:
    KKAKQQDGAA | AMEMQPLKSA | EGGDADDKKK | ANMHKKEKSV | LQGKLTKLAV | 
    400:
    QIGKAGLVMS | AITVIILVLY | FTVDTFVVNK | KPWLTECTPV | YVQYFVKFFI | 
    450:
    IGVTVLVVAV | PEGLPLAVTI | SLAYSVKKMM | KDNNLVRHLD | ACETMGNATA | 
    500:
    ICSDKTGTLT | TNRMTVVQAY | VGDVHYKEIP | DPSSINAKTL | ELLVNAIAIN | 
    550:
    SAYTTKILPP | EKEGALPRQV | GNKTECGLLG | FVLDLRQDYE | PVRSQMPEEK | 
    600:
    LYKVYTFNSV | RKSMSTVIKM | PDESFRMYSK | GASEIVLKKC | CKILSGAGEA | 
    650:
    RVFRPRDRDE | MVKKVIEPMA | CDGLRTICVA | YRDFPSSPEP | DWDNENDILN | 
    700:
    ELTCICVVGI | EDPVRPEVPE | AIRKCQRAGI | TVRMVTGDNI | NTARAIAIKC | 
    750:
    GIIHPGEDFL | CLEGKEFNRR | IRNEKGEIEQ | ERIDKIWPKL | RVLARSSPTD | 
    800:
    KHTLVKGIID | STHTEQRQVV | AVTGDGTNDG | PALKKADVGF | AMGIAGTDVA | 
    850:
    KEASDIILTD | DNFSSIVKAV | MWGRNVYDSI | SKFLQFQLTV | NVVAVIVAFT | 
    900:
    GACITQDSPL | KAVQMLWVNL | IMDTFASLAL | ATEPPTETLL | LRKPYGRNKP | 
    950:
    LISRTMMKNI | LGHAVYQLTL | IFTLLFVGEK | MFQIDSGRNA | PLHSPPSEHY | 
    1000:
    TIIFNTFVMM | QLFNEINARK | IHGERNVFDG | IFRNPIFCTI | VLGTFAIQIV | 
    1050:
    IVQFGGKPFS | CSPLQLDQWM | WCIFIGLGEL | VWGQVIATIP | TSRLKFLKEA | 
    1100:
    GRLTQKEEIP | EEELNEDVEE | IDHAERELRR | GQILWFRGLN | RIQTQIRVVK | 
    1150:
    AFRSSLYEGL | EKPESRTSIH | NFMAHPEFRI | EDSQPHIPLI | DDTDLEEDAA | 
    1198:
    LKQNSSPPSS | LNKNNSAIDS | GINLTTDTSK | SATSSSPGSP | IHSLETSL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse PMCA2
    Cat.:
    E12578m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse PMCA2
    Cat.:
    E12578r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse PMCA2
    Cat.:
    E12578h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse PMCA2
    Cat.:
    U12578r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse PMCA2
    Cat.:
    U12578m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse PMCA2
    Cat.:
    U12578h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse PMCA2
    Cat.:
    P12578Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse PMCA2
    Cat.:
    P12578Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse PMCA2
    Cat.:
    P12578Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse PMCA2
    Monoclonal Antibody for Mouse PMCA2
    Monoclonal Antibody for Mouse PMCA2
    Protein for Mouse PMCA2
    Protein for Mouse PMCA2
    Protein for Mouse PMCA2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in deafwaddler mice."
      Street V.A. , McKee-Johnson J.W. , Fonseca R.C. , Tempel B.L. , Noben-Trauth K.
      Nat. Genet.19:390-394(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;VARIANT DFW SER-243
      strain: C3H/HeJ.
    2. 2.
      "A mouse with a point mutation in plasma membrane Ca2+-ATPase isoform 2 gene showed the reduced Ca2+ influx in cerebellar neurons."
      Ueno T. , Kameyama K. , Hirata M. , Ogawa M. , Hatsuse H. , Takagaki Y. , Ohmura M. , Osawa N. , Kudo Y.
      Neurosci. Res.42:287-297(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT LYS-412
      strain: BALB/C WMS.
    3. 3.
      Lubec G. , Kang S.U.
      Submitted (2007-04) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 16-32; 46-58; 62-77; 80-90; 197-249; 251-270; 305-318; 438-455; 464-477; 489-506; 537-543; 554-561; 570-576; 581-588; 593-601; 626-632; 684-694; 757-767; 785-818; 825-832; 931-938; 976-983; 1104-1116; 1130-1152 AND 1164-1180
      strain: C57BL/6.
      tissue: Brain.
    4. 4.
      "Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2."
      Kozel P.J. , Friedman R.A. , Erway L.C. , Yamoah E.N. , Liu L.H. , Riddle T. , Duffy J.J. , Doetschman T. , Miller M.L. , Cardell E.L. , Shull G.E.
      J. Biol. Chem.273:18693-18696(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons."
      Krizaj D. , Demarco S.J. , Johnson J. , Strehler E.E. , Copenhagen D.R.
      J. Comp. Neurol.451:1-21(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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