ATP2B4 ELISA Kit for Human(Homo sapiens) | EIAab.comATP2B4 ELISA Kit for Human(Homo sapiens)

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ATP2B4 (Gene name),

Plasma membrane calcium-transporting ATPase 4 (Protein name ), AT2B4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ATP2B4(ATP2B2;MXRA1);

Protein name:

Plasma membrane calcium-transporting ATPase 4(PMCA4);

Alternative:

Plasma membrane calcium ATPase isoform 4;Matrix-remodeling-associated protein 1;Plasma membrane calcium pump isoform 4;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

1241

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1241:

RVLLLDGEVT | PYANTNNNAV | DCNQVQLPQS | DSSLQSLETS | V

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF12424

UniGene:

Hs.343522

String:

P23634

MIM:

108732

STRING:

9606.ENSP00000350310

SMR:

P23634

KEGG:

hsa:493

Uniprot:

P23634

FOR

ELISA Kit for Human PMCA4

CLIA Kit for Human PMCA4

Polyclonal Antibody for Human PMCA4

Monoclonal Antibody for Human PMCA4

Protein for Human PMCA4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Peptide sequence analysis and molecular cloning reveal two calcium pump isoforms in the human erythrocyte membrane."
Strehler E.E. , James P. , Fischer R. , Heim R. , Vorherr T.E. , Filoteo A.G. , Penniston J.T. , Carafoli E.
J. Biol. Chem.265:2835-2842(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM XB);PARTIAL PROTEIN SEQUENCE
tissue: Erythrocyte.
2.

"Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and characterization of an alternately spliced form of PMCA4 at the cDNA and genomic levels."
Brandt P. , Neve R.L. , Kammesheidt A. , Rhoads R.E. , Vanaman T.C.
J. Biol. Chem.267:4376-4385(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM XA)
tissue: Fetal brain.
3.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM XB)
tissue: Fetal kidney.
4.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM XA)
tissue: Brain.
7.

"Analysis of mRNA expression and cloning of a novel plasma membrane Ca(2+)-ATPase splice variant in human heart."
Santiago-Garcia J. , Mas-Oliva J. , Saavedra D. , Zarain-Herzberg A.
Mol. Cell. Biochem.155:173-182(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS XA; XB; XK; ZA; ZB AND ZK)
tissue: Heart muscle.
8.

"Identification and primary structure of a calmodulin binding domain of the Ca2+ pump of human erythrocytes."
James P. , Maeda M. , Fischer R. , Verma A.K. , Krebs J. , Penniston J.T. , Carafoli E.
J. Biol. Chem.263:2905-2910(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1085-1153 (ISOFORMS XB/ZB);CALMODULIN-BINDING SUBDOMAIN A
9.

"A C-terminal, calmodulin-like regulatory domain from the plasma membrane Ca2+-pumping ATPase."
Brandt P. , Zurini M. , Neve R.L. , Rhoads R.E. , Vanaman T.C.
Proc. Natl. Acad. Sci. U.S.A.85:2914-2918(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1177-1190
10.

"Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes."
Stauffer T.P. , Hilfiker H. , Carafoli E. , Strehler E.E.
J. Biol. Chem.268:25993-26003(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS X AND Z)
tissue: Heart.
11.

Stauffer T.P. , Hilfiker H. , Carafoli E. , Strehler E.E.
J. Biol. Chem.269:32022-32022(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
12.

"Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants."
Goellner G.M. , DeMarco S.J. , Strehler E.E.
Ann. N. Y. Acad. Sci.986:461-471(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PDZD11
13.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters."
Krapivinsky G. , Krapivinsky L. , Stotz S.C. , Manasian Y. , Clapham D.E.
Proc. Natl. Acad. Sci. U.S.A.108:19234-19239(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SLC35G1 AND STIM1
15.

"NMR solution structure of a complex of calmodulin with a binding peptide of the Ca(2+) pump."
Elshorst B. , Hennig M. , Foersterling H. , Diener A. , Maurer M. , Schulte P. , Schwalbe H. , Griesinger C. , Krebs J. , Schmid H. , Vorherr T.E. , Carafoli E.
Biochemistry38:12320-12332(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1086-1104 IN COMPLEX WITH CALMODULIN

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