Protein name:
Probable phospholipid-transporting ATPase IC ;
Alternative:
ATPase class I type 8B member 1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
May play a role in the transport of aminophospholipids from the outer to the inner leaflet of various membranes and the maintenance of asymmetric distribution of phospholipids in the canicular membrane. Plays a role in bile salt homeostasis.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MSTERDSETT | FDEESQPNDE | VVPYSDDETE | DELEDQGSTV | EPEQNRVNRE |
100:
AEKKRETFRK | DCTWQVKAND | RKFHEQPHFM | NTKFFCIKES | KYASNAIKTY |
150:
KYNGFTFLPM | NLFEQFKRAA | NFYFLILLIL | QAIPQISTLA | WYTTLVPLLL |
200:
VLGITAIKDL | VDDVARHKMD | KEINNRTCEV | IKDGRFKIIK | WKDIQVGDVI |
250:
RLKKNDFIPA | DILLLSSSEP | NSLCYVETAE | LDGETNLKFK | MALEITDQYL |
300:
QIEDNLATFD | GFIECEEPNN | RLDKFTGTLF | WKNQSFPLDA | DKILLRGCVI |
350:
RNTDVCHGLV | IFAGADTKIM | KNSGKTRFKR | TKIDYLMNYM | VYTIFIVLIL |
400:
VSAGLAIGHA | YWEAQVGNYS | WYLYDGENAT | PSYRGFLNFW | GYIIVLNTMV |
450:
PISLYVSVEV | IRLGQSHFIN | WDLQMYYAEK | DTPAKARTTT | LNEQLGQIHY |
500:
IFSDKTGTLT | QNIMTFKKCC | INGTIYGDHR | DASQHSHSKI | ELVDFSWNTF |
550:
ADGKLAFYDH | YLIEQIQSGK | EPEVRQFFFL | LSICHTVMVD | RIDGQINYQA |
600:
ASPDEGALVN | AARNFGFAFL | ARTQNTITVS | ELGSERTYNV | LAILDFNSDR |
650:
KRMSIIVRTP | EGSIRLYCKG | ADTVIYERLH | RMNPTKQETQ | DALDIFASET |
700:
LRTLCLCYKE | IEEKEFTEWN | NKFMAASVAS | SNRDEALDKV | YEEIEKDLIL |
750:
LGATAIEDKL | QDGVPETISK | LAKADIKIWV | LTGDKKETAE | NIGFACELLT |
800:
EDTTICYGED | INSLLHTRME | NQRNRGGVSA | KFAPPVYEPF | FPPGENRALI |
850:
ITGSWLNEIL | LEKKTKRSKI | LKLKFPRTEE | ERRMRSQSRR | RLEEKKEQRQ |
900:
KNFVDLACEC | SAVICCRVTP | KQKAMVVDLV | KRYKKAITLA | IGDGANDVNM |
950:
IKTAHIGVGI | SGQEGMQAVM | SSDYSFAQFR | YLQRLLLVHG | RWSYIRMCKF |
1000:
LRYFFYKNFA | FTLVHFWYSF | FNGYSAQTAY | EDWFITLYNV | LYSSLPVLLM |
1050:
GLLDQDVSDK | LSLRFPGLYV | VGQRDLLFNY | KRFFVSLLHG | VLTSMVLFFI |
1100:
PLGAYLQTVG | QDGEAPSDYQ | SFAVTVASAL | VITVNFQIGL | DTSYWTFVNA |
1150:
FSIFGSIALY | FGIMFDFHSA | GIHVLFPSAF | QFTGTASNAL | RQPYIWLTII |
1200:
LTVAVCLLPV | VAIRFLSMTI | WPSESDKIQK | HRKRLKAEEQ | WKRRQSVFRR |
1250:
GVSSRRSAYA | FSHQRGYADL | ISSGRSIRKK | RSPLDAIIAD | GTAEYRRTVE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Probable phospholipid-transporting ATPase IC
ELISA Kit for Mouse Probable phospholipid-transporting ATPase IC
CLIA Kit for Mouse Probable phospholipid-transporting ATPase IC
CLIA Kit for Mouse Probable phospholipid-transporting ATPase IC
Polyclonal Antibody for Mouse Probable phospholipid-transporting ATPase IC
Polyclonal Antibody for Mouse Probable phospholipid-transporting ATPase IC
Monoclonal Antibody for Mouse Probable phospholipid-transporting ATPase IC
Monoclonal Antibody for Mouse Probable phospholipid-transporting ATPase IC
Protein for Mouse Probable phospholipid-transporting ATPase IC
Protein for Mouse Probable phospholipid-transporting ATPase IC
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;DISRUPTION PHENOTYPE
strain :
129 .
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
NOD .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1223;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
5.
"ATP8B1 is essential for maintaining normal hearing."
Stapelbroek J.M.
,
Peters T.A.
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van Beurden D.H.
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Curfs J.H.
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Joosten A.
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Proc. Natl. Acad. Sci. U.S.A.106:9709-9714(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;MUTAGENESIS OF GLY-308
6.
"Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia."
Ray N.B.
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Durairaj L.
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Nat. Med.16:1120-1127(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION
7.
"Complementary functions of the flippase ATP8B1 and the floppase ABCB4 in maintaining canalicular membrane integrity."
Groen A.
,
Romero M.R.
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Dixon P.H.
,
Wooding C.
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Gastroenterology141:1927-1937(2011)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION