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Index > Protein center > Atad5(Gene name) > Mouse
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  • Atad5 (Gene name),
  • ATPase family AAA domain-containing protein 5 (Protein name ),  ATAD5_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Atad5(Frag1);
    Protein name:
    ATPase family AAA domain-containing protein 5;
    Alternative:
    Chromosome fragility-associated gene 1 protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with RB1 predominantly in G1 phase via its LXCXE motif. Interacts with RAD9A in growing cells. The interaction with RAD9A is reduced after exposure to DNA replication-inhibiting agents.
    Function:
    Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    1826
    Sequence:
    50:
    MVGVLSMAAA | AAPLPVKDYE | IEPCKKRRKD | DDNSSCETIT | KYLSPIGKTG | 
    100:
    DKVFSPPKPS | NILHYFRKTS | LTTEKPQSTK | AYKIKPSPPL | LVGNSKDCKT | 
    150:
    PLEVFSNREF | KRKRKRVSLS | SQLNDIKIQD | ECPVEISNND | SKEDGGLSDC | 
    200:
    VESSASVSLY | KEHVEVLAES | IEDSRNQPNT | KSSKKKVNPK | QCTTKSDDRI | 
    250:
    LRKRKRSKVT | GQSESVPLAD | ELSLPEDGGK | DSKLTKPSLA | EENDSRTHAT | 
    300:
    KRADLKESTI | TVSYEEFVKS | HKAAKVEEIP | DPAVPACVPS | GPGEAVKSGS | 
    350:
    EGELSGSCEP | SPQLHLKTVT | VLAQVHPTPP | KKKGKIPPIF | LKQKQPELEN | 
    400:
    SLSDPENEQP | VQKRKSNVVI | QEGQLELAVL | EAWNSEASVP | KCSMEERQQF | 
    450:
    MRAFRQPPPD | TLKNGFKKPL | EKQKDPSEKS | VHEGDSSSEK | IIENPNIQRV | 
    500:
    SSQGCLQSHA | DRGSFPKEKS | KKPNKKGKKT | RTTAGGNREE | NIQKEKTAFS | 
    550:
    LKDEQDQNSL | RRSVRQKSEV | LKSNALLNSE | NLVCEDTAHD | SVQMSLCNRN | 
    600:
    KSRSSSTPTR | DMVTHHRAEP | GSSLEYVSTR | QPIRRSLRSC | STPATNALGG | 
    650:
    TESEDAQDTI | PVKASTPKSA | RTSEKHNLYT | AELIIVSSDS | ESPIRMKFTR | 
    700:
    ISTPKKSKKS | SKKSETTEEE | LTSQKKKANS | TSKNISKAKE | LIEEAKAFQI | 
    750:
    GGSKTEETVV | PLRRSSRHQA | RSAKEKSPEI | DDSVIVIDSS | PTSIREPEKS | 
    800:
    QKKLQNLNDV | LGKKLNKSSK | NVPGKMKIAP | LFLAKRTKRA | AIPVFDLDES | 
    850:
    SQDSSEQTQD | CDVQFKAKRD | FLMSGLPDLL | KRQIAKKAAA | LDVYNAVSTS | 
    900:
    FQRVVHVQQK | DDEYWLWHLK | PPSCPLLTEF | KELNTKVTDL | SEYVVAFGEF | 
    950:
    STLNPNPRSN | PAAVMMRTRK | DFTKEVRNLL | LEEIKCSNPE | FSLEKYFPLL | 
    1000:
    LKKRIEHQVL | CEGHGKQASP | QLQPDVSQKE | TKRKQVATGN | QKSKRKRQNE | 
    1050:
    YSVSPEEMKG | RSKDLDERIS | SSCTNLDPSR | DSGTEDMLWT | EKYQPQNSNE | 
    1100:
    LIGNELAVKK | LHSWLKDWKR | RAELEERHNL | KGKRDEKEEG | ILDLSDSTDF | 
    1150:
    KGSSDDEENR | LCNTVLITGP | TGVGKTAAVY | ACAQELGFKI | FEVNASSQRS | 
    1200:
    GRQILSQLKE | ATQSHQVDKQ | GVNSQKPCFF | NNYNIGKSPK | KLNSPGKVVT | 
    1250:
    SPRKLPPSSP | KTSGQKRALL | PKTLANYFKV | SSKSKSNDDV | GALMGDDKGV | 
    1300:
    KNSSLEQRQL | IQTKSTNANN | SHIKDVGAEE | SNRKKATSLI | LFEEVDVIFD | 
    1350:
    EDAGFLNAVK | TFMATTKRPV | ILTTSDPTFS | LVFDGCFEEI | NFSIPSLLNV | 
    1400:
    ASYLQVICLV | ENFRTDFKDF | VTLLTANACD | IRKSILYLQF | WIRSGGGILE | 
    1450:
    ERPLSHCREN | SRNTLVCSED | GSDANINSKK | PKRNRVALPR | CDTGCAEALF | 
    1500:
    GLKNIASPSQ | DLLSLLKHKI | TTKEEWQKLI | QVLTEFHVQN | IDLLHSNLEV | 
    1550:
    ILPLPVHVVP | DVRGAYGFPV | TTQASAPASM | GHLTRKQSKD | QPLRKSQKRK | 
    1600:
    QKKMVILDDS | DLFDTGLDFS | GELPSLSPAP | SLSVEDNIRR | DSNPEIKTQN | 
    1650:
    SGFKPHSVPQ | PPKTLAEKKC | CMLVSHCLNS | LSEFMENMSF | IDALLTDPGE | 
    1700:
    QNELGRSAFH | WTNGRVKSGL | CDEFSLENRD | RWAPQSAGEL | KATAEALSFT | 
    1750:
    ECSSTISKAL | ESLNSCKQLE | RDPTNELTVC | VSQRRHDACF | RQSAANLDNA | 
    1800:
    DKRMAVIKSV | FSSRSFLTLG | NKQASIIDYL | PTLRNICRTE | KLKEQEKNKR | 
    1826:
    RFLHYFEGIH | LEIPEETITT | LAADFP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ATPase family AAA domain-containing protein 5
    ELISA Kit for Mouse ATPase family AAA domain-containing protein 5
    CLIA Kit for Mouse ATPase family AAA domain-containing protein 5
    CLIA Kit for Mouse ATPase family AAA domain-containing protein 5
    Polyclonal Antibody for Mouse ATPase family AAA domain-containing protein 5
    Polyclonal Antibody for Mouse ATPase family AAA domain-containing protein 5
    Monoclonal Antibody for Mouse ATPase family AAA domain-containing protein 5
    Monoclonal Antibody for Mouse ATPase family AAA domain-containing protein 5
    Protein for Mouse ATPase family AAA domain-containing protein 5
    Protein for Mouse ATPase family AAA domain-containing protein 5

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis."
      Ishii H. , Inageta T. , Mimori K. , Saito T. , Sasaki H. , Isobe M. , Mori M. , Croce C.M. , Huebner K. , Ozawa K. , Furukawa Y.
      Proc. Natl. Acad. Sci. U.S.A.102:9655-9660(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH RAD9A AND RB1;TISSUE SPECIFICITY
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-762 AND 1463-1826 (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Cecum.
      tissue: Eye.
      tissue: Lung.
      tissue: Stomach.
      tissue: Wolffian duct.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-472 (ISOFORM 1)
      strain: FVB/N.
      tissue: Mammary tumor.
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