Gene name:
ATG4C (APG4C;AUTL1;AUTL3) ;
Protein name:
Cysteine protease ATG4C ;
Alternative:
Autophagin-3 ;AUT-like 3 cysteine endopeptidase ;Autophagy-related protein 4 homolog C ;Autophagy-related cysteine endopeptidase 3 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MEATGTDEVD | KLKTKFISAW | NNMKYSWVLK | TKTYFSRNSP | VLLLGKCYHF |
100:
KYEDEDKTLP | AESGCTIEDH | VIAGNVEEFR | KDFISRIWLT | YREEFPQIEG |
150:
SALTTDCGWG | CTLRTGQMLL | AQGLILHFLG | RAWTWPDALN | IENSDSESWT |
200:
SHTVKKFTAS | FEASLSGERE | FKTPTISLKE | TIGKYSDDHE | MRNEVYHRKI |
250:
ISWFGDSPLA | LFGLHQLIEY | GKKSGKKAGD | WYGPAVVAHI | LRKAVEEARH |
300:
PDLQGITIYV | AQDCTVYNSD | VIDKQSASMT | SDNADDKAVI | ILVPVRLGGE |
350:
RTNTDYLEFV | KGILSLEYCV | GIIGGKPKQS | YYFAGFQDDS | LIYMDPHYCQ |
400:
SFVDVSIKDF | PLETFHCPSP | KKMSFRKMDP | SCTIGFYCRN | VQDFKRASEE |
450:
ITKMLKFSSK | EKYPLFTFVN | GHSRDYDFTS | TTTNEEDLFS | EDEKKQLKRF |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Cysteine protease ATG4C
ELISA Kit for Human Cysteine protease ATG4C
CLIA Kit for Human Cysteine protease ATG4C
CLIA Kit for Human Cysteine protease ATG4C
Polyclonal Antibody for Human Cysteine protease ATG4C
Polyclonal Antibody for Human Cysteine protease ATG4C
Monoclonal Antibody for Human Cysteine protease ATG4C
Monoclonal Antibody for Human Cysteine protease ATG4C
Protein for Human Cysteine protease ATG4C
Protein for Human Cysteine protease ATG4C
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES