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Index > Protein center > Atg4c(Gene name) > Mouse
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  • Atg4c (Gene name),
  • Cysteine protease ATG4C (Protein name ),  ATG4C_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    Atg4c(Apg4c;Autl3);
    Protein name:
    Cysteine protease ATG4C;
    Alternative:
    Autophagin-3;AUT-like 3 cysteine endopeptidase;Autophagy-related protein 4 homolog C;Autophagy-related cysteine endopeptidase 3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    458
    Sequence:
    50:
    MEASGTDEVD | KLKTKFISAW | NNMKYSWVLK | TKTYFSRNSP | VLLLGKCYHF | 
    100:
    KYEDESKMLP | ARSGCAIEDH | VIAGNVEEFR | KDFISRIWLT | YREEFPQIEA | 
    150:
    SALTTDCGWG | CTLRTGQMLL | AQGLILHFLG | RAWTWPDALH | IENADSDSWT | 
    200:
    SNTVKKFTAS | FEASLSGDRE | LRTPAVSLKE | TSGKCPDDHA | VRNEAYHRKI | 
    250:
    ISWFGDSPVA | VFGLHRLIEF | GKKSGKKAGD | WYGPAVVAHI | LRKAVEEARH | 
    300:
    PDLQGLTIYV | AQDCTVYNSD | VIDKQTDSVT | AGDARDKAVI | ILVPVRLGGE | 
    350:
    RTNTDYLEFV | KGVLSLEYCV | GIIGGKPKQS | YYFAGFQDDS | LIYMDPHYCQ | 
    400:
    SFVDVSIKDF | PLETFHCPSP | KKMSFRKMDP | SCTIGFYCRN | VQDFERASEE | 
    450:
    ITKMLKISSK | EKYPLFTFVN | GHSKDFDFTS | TAASEEDLFS | EDERKNFKRF | 
    458:
    STEEFVLL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cysteine protease ATG4C
    ELISA Kit for Mouse Cysteine protease ATG4C
    CLIA Kit for Mouse Cysteine protease ATG4C
    CLIA Kit for Mouse Cysteine protease ATG4C
    Polyclonal Antibody for Mouse Cysteine protease ATG4C
    Polyclonal Antibody for Mouse Cysteine protease ATG4C
    Monoclonal Antibody for Mouse Cysteine protease ATG4C
    Monoclonal Antibody for Mouse Cysteine protease ATG4C
    Protein for Mouse Cysteine protease ATG4C
    Protein for Mouse Cysteine protease ATG4C

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy."
      Marino G. , Uria J.A. , Puente X.S. , Quesada V. , Bordallo J. , Lopez-Otin C.
      J. Biol. Chem.278:3671-3678(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
    4. 4.
      "Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3."
      Marino G. , Salvador-Montoliu N. , Fueyo A. , Knecht E. , Mizushima N. , Lopez-Otin C.
      J. Biol. Chem.282:18573-18583(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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