Atl1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAtl1 ELISA Kit for Rat(Rattus norvegicus)

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Atl1 (Gene name),

Atlastin-1 (Protein name ), ATLA1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Atl1(Spg3a);

Protein name:

Atlastin-1;

Alternative:

Spastic paraplegia 3A homolog;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homooligomer. Interacts (via N-terminal region) with MAP4K4 (via CNH regulatory domain). Interacts with SPAST; interaction is direct (By similarity). Interacts with REEP5, RTN3 and RTN4 (via the transmembrane region).

Function:

GTPase tethering membranes through formation of trans-homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development.

Subcellular Location:

Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein Cell projection axon

Protein Attributes:

Sequence length:

558

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

558:

EQPEKKKI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q6PST4

STRING:

10116.ENSRNOP00000006918

KEGG:

rno:362750

UniGene:

Rn.135117

Pfam:

PF02263

Uniprot:

Q6PST4

FOR

ELISA Kit for Rat Atlastin-1

CLIA Kit for Rat Atlastin-1

Polyclonal Antibody for Rat Atlastin-1

Monoclonal Antibody for Rat Atlastin-1

Protein for Rat Atlastin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cellular localization, oligomerization, and membrane association of the hereditary spastic paraplegia 3A (SPG3A) protein atlastin."
Zhu P.-P. , Patterson A. , Lavoie B. , Stadler J. , Shoeb M. , Patel R. , Blackstone C.
J. Biol. Chem.278:49063-49071(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY
strain: Sprague-Dawley.
tissue: Brain.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
3.

"SPG3A protein atlastin-1 is enriched in growth cones and promotes axon elongation during neuronal development."
Zhu P.-P. , Soderblom C. , Tao-Cheng J.-H. , Stadler J. , Blackstone C.
Hum. Mol. Genet.15:1343-1353(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF ARG-217; ARG-239 AND HIS-258;DEVELOPMENTAL STAGE
4.

"A class of dynamin-like GTPases involved in the generation of the tubular ER network."
Hu J. , Shibata Y. , Zhu P.-P. , Voss C. , Rismanchi N. , Prinz W.A. , Rapoport T.A. , Blackstone C.
Cell138:549-561(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH REEP5; RTN3 AND RTN4

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