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Index > Protein center > ATP4A(Gene name) > Pig
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  • ATP4A (Gene name),
  • Potassium-transporting ATPase alpha chain 1 (Protein name ),  ATP4A_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ATP4A;
    Protein name:
    Potassium-transporting ATPase alpha chain 1;
    Alternative:
    Proton pump;Gastric H(+)/K(+) ATPase subunit alpha;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Composed of two subunits: alpha (catalytic) and beta.
    Function:
    Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1034
    Sequence:
    50:
    MGKAENYELY | QVELGPGPSG | DMAAKMSKKK | AGRGGGKRKE | KLENMKKEME | 
    100:
    INDHQLSVAE | LEQKYQTSAT | KGLSASLAAE | LLLRDGPNAL | RPPRGTPEYV | 
    150:
    KFARQLAGGL | QCLMWVAAAI | CLIAFAIQAS | EGDLTTDDNL | YLALALIAVV | 
    200:
    VVTGCFGYYQ | EFKSTNIIAS | FKNLVPQQAT | VIRDGDKFQI | NADQLVVGDL | 
    250:
    VEMKGGDRVP | ADIRILQAQG | RKVDNSSLTG | ESEPQTRSPE | CTHESPLETR | 
    300:
    NIAFFSTMCL | EGTAQGLVVN | TGDRTIIGRI | ASLASGVENE | KTPIAIEIEH | 
    350:
    FVDIIAGLAI | LFGATFFIVA | MCIGYTFLRA | MVFFMAIVVA | YVPEGLLATV | 
    400:
    TVCLSLTAKR | LASKNCVVKN | LEAVETLGST | SVICSDKTGT | LTQNRMTVSH | 
    450:
    LWFDNHIHSA | DTTEDQSGQT | FDQSSETWRA | LCRVLTLCNR | AAFKSGQDAV | 
    500:
    PVPKRIVIGD | ASETALLKFS | ELTLGNAMGY | RERFPKVCEI | PFNSTNKFQL | 
    550:
    SIHTLEDPRD | PRHVLVMKGA | PERVLERCSS | ILIKGQELPL | DEQWREAFQT | 
    600:
    AYLSLGGLGE | RVLGFCQLYL | SEKDYPPGYA | FDVEAMNFPT | SGLSFAGLVS | 
    650:
    MIDPPRATVP | DAVLKCRTAG | IRVIMVTGDH | PITAKAIAAS | VGIISEGSET | 
    700:
    VEDIAARLRV | PVDQVNRKDA | RACVINGMQL | KDMDPSELVE | ALRTHPEMVF | 
    750:
    ARTSPQQKLV | IVESCQRLGA | IVAVTGDGVN | DSPALKKADI | GVAMGIAGSD | 
    800:
    AAKNAADMIL | LDDNFASIVT | GVEQGRLIFD | NLKKSIAYTL | TKNIPELTPY | 
    850:
    LIYITVSVPL | PLGCITILFI | ELCTDIFPSV | SLAYEKAESD | IMHLRPRNPK | 
    900:
    RDRLVNEPLA | AYSYFQIGAI | QSFAGFTDYF | TAMAQEGWFP | LLCVGLRPQW | 
    950:
    ENHHLQDLQD | SYGQEWTFGQ | RLYQQYTCYT | VFFISIEMCQ | IADVLIRKTR | 
    1000:
    RLSAFQQGFF | RNRILVIAIV | FQVCIGCFLC | YCPGMPNIFN | FMPIRFQWWL | 
    1034:
    VPMPFGLLIF | VYDEIRKLGV | RCCPGSWWDQ | ELYY
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Pig Potassium-transporting ATPase alpha chain 1
    ELISA Kit for Pig Potassium-transporting ATPase alpha chain 1
    ELISA Kit for Pig Potassium-transporting ATPase alpha chain 1
    ELISA Kit for Pig Potassium-transporting ATPase alpha chain 1
    ELISA Kit for Pig Potassium-transporting ATPase alpha chain 1
    ELISA Kit for Pig Potassium-transporting ATPase alpha chain 1
    CLIA Kit for Pig Potassium-transporting ATPase alpha chain 1
    CLIA Kit for Pig Potassium-transporting ATPase alpha chain 1
    CLIA Kit for Pig Potassium-transporting ATPase alpha chain 1
    CLIA Kit for Pig Potassium-transporting ATPase alpha chain 1
    CLIA Kit for Pig Potassium-transporting ATPase alpha chain 1
    CLIA Kit for Pig Potassium-transporting ATPase alpha chain 1
    Polyclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Polyclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Polyclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Polyclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Polyclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Polyclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Monoclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Monoclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Monoclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Monoclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Monoclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Monoclonal Antibody for Pig Potassium-transporting ATPase alpha chain 1
    Protein for Pig Potassium-transporting ATPase alpha chain 1
    Protein for Pig Potassium-transporting ATPase alpha chain 1
    Protein for Pig Potassium-transporting ATPase alpha chain 1
    Protein for Pig Potassium-transporting ATPase alpha chain 1
    Protein for Pig Potassium-transporting ATPase alpha chain 1
    Protein for Pig Potassium-transporting ATPase alpha chain 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "cDNA cloning and sequence determination of pig gastric (H+ + K+)-ATPase."
      Maeda M. , Ishizaki J. , Futai M.
      Biochem. Biophys. Res. Commun.157:203-209(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Structural studies on H+,K+-ATPase: determination of the NH2-terminal amino acid sequence and immunological cross-reactivity with Na+,K+-ATPase."
      Lane L.K. , Kirley T.L. , Ball W.J. Jr.
      Biochem. Biophys. Res. Commun.138:185-192(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-18
    3. 3.
      "Ser-27, Tyr-10 and Tyr-7 in the alpha-chain of pig stomach H+,K(+)-ATPase as Ca(2+)-dependent phosphorylatable sites by intrinsic and extrinsic protein kinases."
      Togawa K. , Kaya S. , Shimada A. , Imagawa T. , Maardh S. , Corbin J. , Kikkawa U. , Taniguchi K.
      Biochem. Biophys. Res. Commun.227:810-815(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-11;PHOSPHORYLATION AT SER-27
    4. 4.
      "Determination of the epitope for the inhibitory monoclonal antibody 5-B6 on the catalytic subunit of gastric Mg(2+)-dependent H(+)-transporting and K(+)-stimulated ATPase."
      Van Uem T.J. , Swarts H.G. , De Pont J.J.
      Biochem. J.280:243-248(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACTIVE SITE ASP-386
    5. 5.
      "Reversible phosphorylation of both Tyr7 and Tyr10 in the alpha-chain of pig stomach H+,K(+)-ATPase by a membrane-bound kinase and a phosphatase."
      Togawa K. , Ishiguro T. , Kaya S. , Shimada A. , Imagawa T. , Taniguchi K.
      J. Biol. Chem.270:15475-15478(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-7 AND TYR-10
    6. 6.
      "Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressant."
      Abe K. , Tani K. , Fujiyoshi Y.
      Nat. Commun.2:155-155(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY ELECTRON MICROSCOPY (7.0 ANGSTROMS) IN COMPLEX WITH ATP4B AND INHIBITOR;SUBCELLULAR LOCATION
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