Protein name:
Copper-transporting ATPase 1 ;
Alternative:
Menkes disease-associated protein homolog ;Copper pump 1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.
Subcellular Location:
Golgi apparatus
trans-Golgi network membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Constitutively cycles between the trans-Golgi network (TGN) and the plasma membrane. Predominantly found in the TGN and relocalized to the plasma membrane in response to elevated copper levels.
Protein Attributes:
50:
MEPNMDANSI | TITVEGMTCI | SCVRTIEQQI | GKVNGVHHIK | VSLEEKSATV |
100:
IYNPKLQTPK | TLQEAIDDMG | FDALLHNANP | LPVLTNTVFL | TVTAPLALPW |
150:
DHIQSTLLKT | KGVTGVKISP | QQRSAVVTII | PSVVSANQIV | ELVPDLSLDM |
200:
GTQEKKSGTS | EEHSTPQAGE | VLLKMRVEGM | TCHSCTSTIE | GKVGKLQGVQ |
250:
RIKVSLDNQE | ATIVYQPHLI | TAEEIKKQIE | AVGFPAFIKK | QPKYLKLGAI |
300:
DVERLKSTPV | KSSEGSQQKS | PAYPSDSAIT | FTIDGMHCKS | CVSNIESALS |
350:
TLQYVSSIVV | SLENRSAIVK | YNASLVTPEI | LRKAIEAVSP | GQYRVSISSE |
400:
VESPTSSPSS | SSLQKMPLNL | VSQPLTQEVV | ININGMTCNS | CVQSIEGVIS |
450:
KKPGVKSIHV | SLTNSTGTIE | YDPLLTSPEP | LREAIEDMGF | DAVLPADMKE |
500:
PLVVIAQPSL | ETPLLPSTTE | PENVMTPVQN | KCYIQVSGMT | CASCVANIER |
550:
NLRREEGIYS | VLVALMAGKA | EVRYNPAVIQ | PRVIAELIRE | LGFGAVVMEN |
600:
AGEGNGILEL | VVRGMTCASC | VHKIESTLTK | HKGIFYCSVA | LATNKAHIKY |
650:
DPEIIGPRDI | IHTIGNLGFE | ASLVKKDRSA | NHLDHKREIK | QWRGSFLVSL |
700:
FFCIPVMGLM | IYMMVMDHHL | ATLNHNQNMS | NEEMINMHSS | MFLERQILPG |
750:
LSIMNLLSLL | LCLPVQFCGG | WYFYIQAYKA | LRHKTANMDV | LIVLATTIAF |
800:
AYSLVILLVA | MYERAKVNPI | TFFDTPPMLF | VFIALGRWLE | HIAKGKTSEA |
850:
LAKLISLQAT | EATIVTLNSE | NLLLSEEQVD | VELVQRGDII | KVVPGGKFPV |
900:
DGRVIEGHSM | VDESLITGEA | MPVAKKPGST | VIAGSINQNG | SLLIRATHVG |
950:
ADTTLSQIVK | LVEEAQTSKA | PIQQFADKLS | GYFVPFIVLV | SIVTLLVWII |
1000:
IGFQNFEIVE | AYFPGYNRSI | SRTETIIRFA | FQASITVLCI | ACPCSLGLAT |
1050:
PTAVMVGTGV | GAQNGILIKG | GEPLEMAHKV | KVVVFDKTGT | ITHGTPVVNQ |
1100:
VKVLVESNKI | SRNKILAIVG | TAESNSEHPL | GAAVTKYCKQ | ELDTETLGTC |
1150:
TDFQVVPGCG | ISCKVTNIEG | LLHKSNLKIE | ENNIKNASLV | QIDAINEQSS |
1200:
PSSSMIIDAH | LSNAVNTQQY | KVLIGNREWM | IRNGLVISND | VDESMIEHER |
1250:
RGRTAVLVTI | DDELCGLIAI | ADTVKPEAEL | AVHILKSMGL | EVVLMTGDNS |
1300:
KTARSIASQV | GITKVFAEVL | PSHKVAKVKQ | LQEEGKRVAM | VGDGINDSPA |
1350:
LAMASVGIAI | GTGTDVAIEA | ADVVLIRNDL | LDVVASIDLS | RKTVKRIRIN |
1400:
FVFALIYNLI | GIPIAAGVFL | PIGLVLQPWM | GSAAMAASSV | SVVLSSLFLK |
1450:
LYRKPTYDNY | ELRPRSHTGQ | RSPSEISVHV | GIDDTSRNSP | RLGLLDRIVN |
1492:
YSRASINSLL | SDKRSLNSVV | TSEPDKHSLL | VGDFREDDDT | TL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Rat Copper-transporting ATPase 1
ELISA Kit for Rat Copper-transporting ATPase 1
ELISA Kit for Rat Copper-transporting ATPase 1
CLIA Kit for Rat Copper-transporting ATPase 1
CLIA Kit for Rat Copper-transporting ATPase 1
CLIA Kit for Rat Copper-transporting ATPase 1
Polyclonal Antibody for Rat Copper-transporting ATPase 1
Polyclonal Antibody for Rat Copper-transporting ATPase 1
Polyclonal Antibody for Rat Copper-transporting ATPase 1
Monoclonal Antibody for Rat Copper-transporting ATPase 1
Monoclonal Antibody for Rat Copper-transporting ATPase 1
Monoclonal Antibody for Rat Copper-transporting ATPase 1
Protein for Rat Copper-transporting ATPase 1
Protein for Rat Copper-transporting ATPase 1
Protein for Rat Copper-transporting ATPase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Astrocyte .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1204;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]