Atxn1l ELISA Kit for Mouse(Mus musculus) | EIAab.comAtxn1l ELISA Kit for Mouse(Mus musculus)

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Atxn1l (Gene name),

Ataxin-1-like (Protein name ), ATX1L_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Atxn1l(Boat);

Protein name:

Ataxin-1-like;

Alternative:

Brother of ataxin-1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer. Interacts (via AXH domain) with NCOR2 (By similarity). Interacts with ATXN1 and CIC.

Function:

Can suppress the cytotoxicity of ATXN1 in spinocerebellar ataxia type 1 (SCA1).

Subcellular Location:

Nucleus Cell projection dendrite Forms nuclear foci. Colocalizes with NCOR2 and HDAC3. Distributed beyond the nucleus into the cell body and dendrites in Purkinje cells and in inferior olive cells.

Protein Attributes:

Sequence length:

687

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

687:

FQRFSMQGEE | ARAAMLRPSF | IPQEVKLSIE | GRSNAGK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10090.ENSMUSP00000090850

SMR:

P0C7T6

Pfam:

PF08517

UniGene:

Mm.276770

KEGG:

mmu:52335

String:

P0C7T6

Uniprot:

P0C7T6

FOR

ELISA Kit for Mouse Ataxin-1-like

CLIA Kit for Mouse Ataxin-1-like

Polyclonal Antibody for Mouse Ataxin-1-like

Monoclonal Antibody for Mouse Ataxin-1-like

Protein for Mouse Ataxin-1-like

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
2.

"Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1."
Mizutani A. , Wang L. , Rajan H. , Vig P.J.S. , Alaynick W.A. , Thaler J.P. , Tsai C.-C.
EMBO J.24:3339-3351(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
3.

"Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes."
Bowman A.B. , Lam Y.C. , Jafar-Nejad P. , Chen H.-K. , Richman R. , Samaco R.C. , Fryer J.D. , Kahle J.J. , Orr H.T. , Zoghbi H.Y.
Nat. Genet.39:373-379(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATXN1 AND CIC

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