Protein name:
Advillin ;
Alternative:
p92 ;Actin-binding protein DOC6 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Associates (via C-terminus) with actin. Interacts with F-actin (By similarity). Interacts with SCARF1; the interaction occurs in embryonic dorsal root ganglions at 18 dpc and induces neurite-like outgrowth.
Function:
Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.
Subcellular Location:
Cytoplasm
cytoskeleton
Cell projection
Cell projection
axon
Protein Attributes:
50:
MSLSSAFRAV | SNDPRIITWR | IEKMELALVP | LSAHGNFYEG | DCYIVLSTRR |
100:
VGSLLSQNIH | FWIGKDSSQD | EQSCAAIYTT | QLDDYLGGSP | VQHREVQYHE |
150:
SDTFRGYFKQ | GIIYKKGGVA | SGMKHVETNT | YDVKRLLHVK | GKRNIQATEV |
200:
EMSWDSFNRG | DVFLLDLGMV | IIQWNGPESN | SGERLKAMLL | AKDIRDRERG |
250:
GRAEIGVIEG | DKEAASPGLM | TVLQDTLGRR | SMIKPAVSDE | IMDQQQKSSI |
300:
MLYHVSDTAG | QLSVTEVATR | PLVQDLLNHD | DCYILDQSGT | KIYVWKGKGA |
350:
TKVEKQAAMS | KALDFIKMKG | YPSSTNVETV | NDGAESAMFK | QLFQKWSVKD |
400:
QTTGLGKIFS | TGKIAKIFQD | KFDVSLLHTK | PEVAAQERMV | DDGKGQVEVW |
450:
RIENLELVPV | EYQWHGFFYG | GDCYLVLYTY | DVNGKPHYIL | YIWQGRHASR |
500:
DELAASAYRA | VEVDQQFDGA | PVQVRVSMGK | EPRHFMAIFK | GKLVIYEGGT |
550:
SRKGNEEPDP | PVRLFQIHGN | DKSNTKAVEV | SASASSLNSN | DVFLLRTQAE |
600:
HYLWYGKGSS | GDERAMAKEL | VDLLCDGNAD | TVAEGQEPPE | FWDLLGGKTA |
650:
YANDKRLQQE | TLDVQVRLFE | CSNKTGRFLV | TEVTDFTQED | LSPGDVMLLD |
700:
TWDQVFLWIG | AEANATEKKG | ALSTAQEYLV | THPSGRDPDT | PILIIKQGFE |
750:
PPTFTGWFLA | WDPHIWSEGK | SYEQLKNELG | DATAIVRITA | DMKNATLYLN |
800:
PSDGEPKYYP | VEVLLKGQNQ | ELPEDVDPAK | KENYLSEQDF | VSVFGITRGQ |
819:
FTALPGWKQL | QLKKERGLF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Mouse Advillin
ELISA Kit for Mouse Advillin
ELISA Kit for Mouse Advillin
CLIA Kit for Mouse Advillin
CLIA Kit for Mouse Advillin
CLIA Kit for Mouse Advillin
Polyclonal Antibody for Mouse Advillin
Polyclonal Antibody for Mouse Advillin
Polyclonal Antibody for Mouse Advillin
Monoclonal Antibody for Mouse Advillin
Monoclonal Antibody for Mouse Advillin
Monoclonal Antibody for Mouse Advillin
Protein for Mouse Advillin
Protein for Mouse Advillin
Protein for Mouse Advillin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
strain :
BALB/c .
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
NIH Swiss .
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Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
strain :
NOD .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
6.
"Type F scavenger receptor SREC-I interacts with advillin, a member of the gelsolin/villin family, and induces neurite-like outgrowth."
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J. Biol. Chem.279:40084-40090(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH SCARF1;DEVELOPMENTAL STAGE;TISSUE SPECIFICITY;IDENTIFICATION BY MASS SPECTROMETRY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-85; TYR-748 AND TYR-758;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Mast cell .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;DEVELOPMENTAL STAGE;TISSUE SPECIFICITY;DISRUPTION PHENOTYPE