Axin2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAxin2 ELISA Kit for Rat(Rattus norvegicus)

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Axin2 (Gene name),

Axin-2 (Protein name ), AXIN2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Axin2;

Protein name:

Axin-2;

Alternative:

Axis inhibition protein 2;Axin-like protein(Axil);Conductin;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with SMAD7 and RNF111. Interacts with ANKRD6 (By similarity). Interacts with glycogen synthase kinase-3 beta (GSK3B) and beta-catenin. The interaction between axin and beta-catenin occurs via the armadillo repeats contained in beta-catenin.

Function:

Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

838

Sequence:

50:

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650:

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838:

KKASDEFACG | AVFEEIWDDE | TVLPMYEGRI | LGKVERID

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.162212

KEGG:

rno:29134

Pfam:

PF08833

String:

O70240

STRING:

10116.ENSRNOP00000004898

SMR:

O70240

Uniprot:

O70240

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ELISA Kit for Rat Axin-2

Cat.:

E9563h

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Manual:

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Packing:

96T

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ELISA Kit for Rat Axin-2

Cat.:

E9563m

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96T

ELISA Kit for Rat Axin-2

Cat.:

E9563r

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Packing:

96T

CLIA Kit for Rat Axin-2

Cat.:

U9563h

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Manual:

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96T

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CLIA Kit for Rat Axin-2

Cat.:

U9563m

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MSDS:

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Packing:

96T

CLIA Kit for Rat Axin-2

Cat.:

U9563r

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Packing:

96T

Polyclonal Antibody for Rat Axin-2

Cat.:

P9563Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Axin-2

Cat.:

P9563Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Axin-2

Monoclonal Antibody for Rat Axin-2

Protein for Rat Axin-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos."
Yamamoto H. , Kishida S. , Uochi T. , Ikeda S. , Koyama S. , Asashima M. , Kikuchi A.
Mol. Cell. Biol.18:2867-2875(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH CTNNB1 AND GSK3B;TISSUE SPECIFICITY
tissue: Brain.

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