Gene name:
Tnfaip1 (Edp1) ;
Protein name:
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 ;
Alternative:
Tumor necrosis factor, alpha-induced protein 1, endothelial ;BTB/POZ domain-containing protein TNFAIP1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the BCR(BACURD2) E3 ubiquitin ligase complex, at least composed of CUL3, TNFAIP1/BACURD2 and RBX1. Interacts with RHOA; with a preferrence for RhoA-GDP. Interacts with RHOB. Interacts with PCNA. Interacts with CSNK2B.
Function:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Subcellular Location:
Cytoplasm
Nucleus
Endosome
Colocalizes with RHOB in endosomes.
Protein Attributes:
50:
MSGDTCLCPA | SGAKPKISGF | KGGGLGNKYV | QLNVGGSLYY | TTVRALTRHD |
100:
TMLKAMFSGR | MEVLTDKEGW | ILIDRCGKHF | GTILNYLRDD | TITLPQSRQE |
150:
IQELMAEAKY | YLIQGLVSTC | QTALQDKKDS | YQPVCNIPII | TSLREEDRLI |
200:
ESSTKPVVKL | LYNRSNNKYS | YTSNSDDHLL | KNIELFDKLS | LRFNGRVLFI |
250:
KDVIGDEICC | WSFYGQGRKL | AEVCCTSIVY | ATEKKQTKVE | FPEARIYEET |
300:
LNVLLYETPR | VPDNSLLEAT | SRSRSQASPS | EDEDTFELRD | RVRRIHVKRY |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Chicken
Rat
Human
ELISA Kit for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
ELISA Kit for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
ELISA Kit for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
ELISA Kit for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
CLIA Kit for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
CLIA Kit for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
CLIA Kit for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
CLIA Kit for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Polyclonal Antibody for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Polyclonal Antibody for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Polyclonal Antibody for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Polyclonal Antibody for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Monoclonal Antibody for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Monoclonal Antibody for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Monoclonal Antibody for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Monoclonal Antibody for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Protein for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Protein for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Protein for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Protein for Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.
"The transcriptional landscape of the mammalian genome."
Carninci P.
,
Kasukawa T.
,
Katayama S.
,
Gough J.
,
Frith M.C.
,
Maeda N.
,
Oyama R.
,
Ravasi T.
,
Lenhard B.
,
Wells C.
,
Kodzius R.
,
Shimokawa K.
,
Bajic V.B.
,
Brenner S.E.
,
Batalov S.
,
Forrest A.R.
,
Zavolan M.
,
Davis M.J.
,
Wilming L.G.
,
Aidinis V.
,
Allen J.E.
,
Ambesi-Impiombato A.
,
Apweiler R.
,
Aturaliya R.N.
,
Bailey T.L.
,
Bansal M.
,
Baxter L.
,
Beisel K.W.
,
Bersano T.
,
Bono H.
,
Chalk A.M.
,
Chiu K.P.
,
Choudhary V.
,
Christoffels A.
,
Clutterbuck D.R.
,
Crowe M.L.
,
Dalla E.
,
Dalrymple B.P.
,
de Bono B.
,
Della Gatta G.
,
di Bernardo D.
,
Down T.
,
Engstrom P.
,
Fagiolini M.
,
Faulkner G.
,
Fletcher C.F.
,
Fukushima T.
,
Furuno M.
,
Futaki S.
,
Gariboldi M.
,
Georgii-Hemming P.
,
Gingeras T.R.
,
Gojobori T.
,
Green R.E.
,
Gustincich S.
,
Harbers M.
,
Hayashi Y.
,
Hensch T.K.
,
Hirokawa N.
,
Hill D.
,
Huminiecki L.
,
Iacono M.
,
Ikeo K.
,
Iwama A.
,
Ishikawa T.
,
Jakt M.
,
Kanapin A.
,
Katoh M.
,
Kawasawa Y.
,
Kelso J.
,
Kitamura H.
,
Kitano H.
,
Kollias G.
,
Krishnan S.P.
,
Kruger A.
,
Kummerfeld S.K.
,
Kurochkin I.V.
,
Lareau L.F.
,
Lazarevic D.
,
Lipovich L.
,
Liu J.
,
Liuni S.
,
McWilliam S.
,
Madan Babu M.
,
Madera M.
,
Marchionni L.
,
Matsuda H.
,
Matsuzawa S.
,
Miki H.
,
Mignone F.
,
Miyake S.
,
Morris K.
,
Mottagui-Tabar S.
,
Mulder N.
,
Nakano N.
,
Nakauchi H.
,
Ng P.
,
Nilsson R.
,
Nishiguchi S.
,
Nishikawa S.
,
Nori F.
,
Ohara O.
,
Okazaki Y.
,
Orlando V.
,
Pang K.C.
,
Pavan W.J.
,
Pavesi G.
,
Pesole G.
,
Petrovsky N.
,
Piazza S.
,
Reed J.
,
Reid J.F.
,
Ring B.Z.
,
Ringwald M.
,
Rost B.
,
Ruan Y.
,
Salzberg S.L.
,
Sandelin A.
,
Schneider C.
,
Schoenbach C.
,
Sekiguchi K.
,
Semple C.A.
,
Seno S.
,
Sessa L.
,
Sheng Y.
,
Shibata Y.
,
Shimada H.
,
Shimada K.
,
Silva D.
,
Sinclair B.
,
Sperling S.
,
Stupka E.
,
Sugiura K.
,
Sultana R.
,
Takenaka Y.
,
Taki K.
,
Tammoja K.
,
Tan S.L.
,
Tang S.
,
Taylor M.S.
,
Tegner J.
,
Teichmann S.A.
,
Ueda H.R.
,
van Nimwegen E.
,
Verardo R.
,
Wei C.L.
,
Yagi K.
,
Yamanishi H.
,
Zabarovsky E.
,
Zhu S.
,
Zimmer A.
,
Hide W.
,
Bult C.
,
Grimmond S.M.
,
Teasdale R.D.
,
Liu E.T.
,
Brusic V.
,
Quackenbush J.
,
Wahlestedt C.
,
Mattick J.S.
,
Hume D.A.
,
Kai C.
,
Sasaki D.
,
Tomaru Y.
,
Fukuda S.
,
Kanamori-Katayama M.
,
Suzuki M.
,
Aoki J.
,
Arakawa T.
,
Iida J.
,
Imamura K.
,
Itoh M.
,
Kato T.
,
Kawaji H.
,
Kawagashira N.
,
Kawashima T.
,
Kojima M.
,
Kondo S.
,
Konno H.
,
Nakano K.
,
Ninomiya N.
,
Nishio T.
,
Okada M.
,
Plessy C.
,
Shibata K.
,
Shiraki T.
,
Suzuki S.
,
Tagami M.
,
Waki K.
,
Watahiki A.
,
Okamura-Oho Y.
,
Suzuki H.
,
Kawai J.
,
Hayashizaki Y.
more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Amnion .
tissue :
Diencephalon .
tissue :
Lung .
tissue :
Thymus .
3.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Mammary tumor .