Tnfaip1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comTnfaip1 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Tnfaip1(Gene name) > Rat

Tnfaip1 (Gene name),

BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (Protein name ), BACD2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Tnfaip1;

Protein name:

BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2;

Alternative:

Tumor necrosis factor-induced protein 1;BTB/POZ domain-containing protein TNFAIP1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Component of the BCR(BACURD2) E3 ubiquitin ligase complex, at least composed of CUL3, TNFAIP1/BACURD2 and RBX1. Interacts with RHOA; with a preferrence for RhoA-GDP. Interacts with RHOB. Interacts with CSNK2B (By similarity). Interacts with PCNA.

Function:

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis (By similarity). May enhance the PCNA-dependent DNA polymerase delta activity.

Subcellular Location:

Cytoplasm Nucleus Endosome Colocalizes with RHOB in endosomes.

Protein Attributes:

Sequence length:

316

Sequence:

50:

100:

150:

200:

250:

300:

316:

STYDDRQLGH | QSAHRD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:287543

STRING:

10116.ENSRNOP00000012245

Pfam:

PF02214

UniGene:

Rn.18199

Uniprot:

Q7TNY1

FOR

ELISA Kit for Rat BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

CLIA Kit for Rat BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

Polyclonal Antibody for Rat BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

Monoclonal Antibody for Rat BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

Protein for Rat BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning of two rat PDIP1 related genes and their interactions with proliferating cell nuclear antigen."
Zhou J. , Hu X. , Xiong X. , Liu X. , Liu Y. , Ren K. , Jiang T. , Hu X. , Zhang J.
J. Exp. Zool. A Comp. Exp. Biol.303:227-240(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH PCNA
strain: Wistar.
tissue: Liver.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Placenta.

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