Bad ELISA Kit for Rat(Rattus norvegicus) | EIAab.comBad ELISA Kit for Rat(Rattus norvegicus)

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Bad (Gene name),

Bcl2 antagonist of cell death (Protein name ), BAD_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Bad;

Protein name:

Bcl2 antagonist of cell death(BAD);

Alternative:

Bcl-xL/Bcl-2-associated death promoter;Bcl-2-binding component 6;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Forms heterodimers with the anti-apoptotic proteins, Bcl-X(L), Bcl-2 and Bcl-W. Also binds protein S100A10. The Ser-113/Ser-137 phosphorylated form binds 14-3-3 proteins. Interacts with PIM3.

Function:

Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Subcellular Location:

Mitochondrion outer membrane Cytoplasm Upon phosphorylation, locates to the cytoplasm.

Protein Attributes:

Sequence length:

205

Sequence:

50:

100:

150:

200:

205:

STPSQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

O35147

Pfam:

PF10514

UniGene:

Rn.36696

KEGG:

rno:64639

String:

O35147

Uniprot:

O35147

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ELISA Kit for Rat BAD

Cat.:

E15040h

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Manual:

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Packing:

96T

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ELISA Kit for Rat BAD

MSDS:

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ELISA Kit for Rat BAD

Cat.:

E15040m

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Manual:

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Packing:

96T

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CLIA Kit for Rat BAD

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CLIA Kit for Rat BAD

MSDS:

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CLIA Kit for Rat BAD

Cat.:

U15040h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat BAD

Monoclonal Antibody for Rat BAD

Protein for Rat BAD

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Interference of BAD (Bcl-xL/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11."
Hsu S.Y. , Kaipia A. , Zhu L. , Hsueh A.J.W.
Mol. Endocrinol.11:1858-1867(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];MUTAGENESIS OF SER-113 AND SER-137
tissue: Ovary.
2.

"Cloning and expression of the programmed cell death regulator BAD in the rat brain."
D'Agata V. , Magro G. , Travali S. , Musco S. , Cavallaro S.
Neurosci. Lett.243:137-140(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
3.

"Functional characterization of two splice variants of rat BAD and their interaction with Bcl-w in sympathetic neurons."
Hamner S. , Arumae U. , Yu L.-Y. , Sun Y.-F. , Saarma M. , Lindholm D.
Mol. Cell. Neurosci.17:97-106(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ALPHA AND BETA)
tissue: Brain.

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