Banf1 ELISA Kit for Mouse(Mus musculus) | EIAab.comBanf1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Banf1(Gene name) > Mouse

Banf1 (Gene name),

Barrier-to-autointegration factor (Protein name ), BAF_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Banf1(Baf;Bcrp1;L2bp1);

Protein name:

Barrier-to-autointegration factor;

Alternative:

LAP2-binding protein 1;Breakpoint cluster region protein 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer. Heterodimerizes with BAFL. Binds non-specifically to double-stranded DNA, and is found as a hexamer or dodecamer upon DNA binding. Binds to LEM domain-containing nuclear proteins such as LEMD3/MAN1, TMPO/LAP2 and EMD (emerin). Interacts with CRX and LMNA (lamin-A). Binds linker histone H1.1 and core histones H3 with in vitro affinities of 500-900 and 100-200 nM.

Function:

Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging.

Subcellular Location:

Nucleus Cytoplasm Chromosome Significantly enriched at the nuclear inner membrane, diffusely throughout the nucleus during interphase and concentrated at the chromosomes during the M-phase. The phosphorylated form (by VRK1) shows a cytoplasmic localization.

Protein Attributes:

Sequence length:

Sequence:

50:

89:

VLKKDEDLFR | EWLKDTCGAN | AKQSRDCFGC | LREWCDAFL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence: