Protein name:
BAG family molecular chaperone regulator 4 (BAG-4) ;
Alternative:
Silencer of death domains ;Bcl-2-associated athanogene 4 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Binds to the ATPase domain of HSP/HSC70 chaperones. Binds to the death domain of TNFRSF1A in the absence of TNF and thereby prevents binding of adapter molecules such as TRADD or TRAF2. Binds to the death domain of TNFRSF12.
Function:
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MSALRRSGYG | PSDGPSYGRY | YGPGGGDVPV | HPPPPLYPLR | PEPPQPPISW |
100:
RVRGGGPAET | TWLGEGGGGD | GYYPSGGAWP | EPGRAGGSHQ | EQPPYPSYNS |
150:
NYWNSTARSR | APYPSTYPVR | PELQGQSLNS | YTNGAYGPTY | PPGPGANTAS |
200:
YSGAYYAPGY | TQTSYSTEVP | STYRSSGNSP | TPVSRWIYPQ | QDCQTEAPPL |
250:
RGQVPGYPPS | QNPGMTLPHY | PYGDGNRSVP | QSGPTVRPQE | DAWASPGAYG |
300:
MGGRYPWPSS | APSAPPGNLY | MTESTSPWPS | SGSPQSPPSP | PVQQPKDSSY |
350:
PYSQSDQSMN | RHNFPCSVHQ | YESSGTVNND | DSDLLDSQVQ | YSAEPQLYGN |
400:
ATSDHPNNQD | QSSSLPEECV | PSDESTPPSI | KKIIHVLEKV | QYLEQEVEEF |
450:
VGKKTDKAYW | LLEEMLTKEL | LELDSVETGG | QDSVRQARKE | AVCKIQAILE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human BAG-4
ELISA Kit for Human BAG-4
Polyclonal Antibody for Human BAG-4
Polyclonal Antibody for Human BAG-4
Monoclonal Antibody for Human BAG-4
Monoclonal Antibody for Human BAG-4
R&D Technical Data
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Precision
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH TNFRSF1A AND TNFRSF12
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