Baiap2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comBaiap2 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Baiap2(Gene name) > Rat

Baiap2 (Gene name),

Brain-specific angiogenesis inhibitor 1-associated protein 2 (Protein name ), BAIP2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Baiap2;

Protein name:

Brain-specific angiogenesis inhibitor 1-associated protein 2(BAI-associated protein 2;BAI1-associated protein 2);

Alternative:

Insulin receptor tyrosine kinase substrate protein p53;Insulin receptor substrate protein of 53 kDa(IRSp53;Insulin receptor substrate p53);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer. Interacts with CDC42 and RAC1 that have been activated by GTP binding. Binds TIAM1. Interacts with ATN1, BAI1, DIAPH1, EPS8, SHANK1, SHANK2, SHANK3, WASF1 and WASF2. Interacts with ENAH after recruitment of CDC42.

Function:

Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.

Subcellular Location:

Cytoplasm Membrane Peripheral membrane protein Cell projection filopodium Cell projection ruffle Cytoplasm cytoskeleton Detected throughout the cytoplasm in the absence of specific binding partners. Detected in filopodia and close to membrane ruffles. Recruited to actin pedestals that are formed upon infection by bacteria at bacterial attachment sites.

Protein Attributes:

Sequence length:

535

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

535:

QGLDDYGARS | VSRNPFANVH | LKPTVTNDRS | APLLS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.95155

SMR:

Q6GMN2

KEGG:

rno:117542

STRING:

10116.ENSRNOP00000005687

Pfam:

PF08397

String:

Q6GMN2

Uniprot:

Q6GMN2

FOR

ELISA Kit for Rat BAI-associated protein 2

CLIA Kit for Rat BAI-associated protein 2

Polyclonal Antibody for Rat BAI-associated protein 2

Monoclonal Antibody for Rat BAI-associated protein 2

Protein for Rat BAI-associated protein 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Insulin receptor substrate protein p53 localization in rats suggests mechanism for specific polyglutamine neurodegeneration."
Thomas E.A. , Foye P.E. , Alvarez C.E. , Usui H. , Sutcliffe J.G.
Neurosci. Lett.309:145-148(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
strain: Sprague-Dawley.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Lung.
3.

Lubec G. , Chen W.-Q.
Submitted (2007-04) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 12-18 AND 41-50;IDENTIFICATION BY MASS SPECTROMETRY
strain: Sprague-Dawley.
tissue: Hippocampus.
4.

"Distinctive tissue distribution and phosphorylation of IRSp53 isoforms."
Okamura-Oho Y. , Miyashita T. , Yamada M.
Biochem. Biophys. Res. Commun.289:957-960(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;MUTAGENESIS OF TYR-17; TYR-115 AND TYR-178;ALTERNATIVE SPLICING;TISSUE SPECIFICITY
5.

"Tiam1-IRSp53 complex formation directs specificity of rac-mediated actin cytoskeleton regulation."
Connolly B.A. , Rice J. , Feig L.A. , Buchsbaum R.J.
Mol. Cell. Biol.25:4602-4614(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TIAM1

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