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Index > Protein center > BCL11A(Gene name) > Human
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  • BCL11A (Gene name),
  • B-cell lymphoma/leukemia 11A (Protein name ),  BC11A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    BCL11A(CTIP1;EVI9;KIAA1809;ZNF856);
    Protein name:
    B-cell lymphoma/leukemia 11A(BCL-11A);
    Alternative:
    COUP-TF-interacting protein 1;B-cell CLL/lymphoma 11A;Zinc finger protein 856;Ecotropic viral integration site 9 protein homolog(EVI-9);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with TFCOUP1, PIAS3, ARP1 and EAR2.
    Function:
    Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.
    Subcellular Location:
    Cytoplasm Nucleus Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles.
    Protein Attributes:
    Sequence length:
    835
    Sequence:
    50:
    MSRRKQGKPQ | HLSKREFSPE | PLEAILTDDE | PDHGPLGAPE | GDHDLLTCGQ | 
    100:
    CQMNFPLGDI | LIFIEHKRKQ | CNGSLCLEKA | VDKPPSPSPI | EMKKASNPVE | 
    150:
    VGIQVTPEDD | DCLSTSSRGI | CPKQEHIADK | LLHWRGLSSP | RSAHGALIPT | 
    200:
    PGMSAEYAPQ | GICKDEPSSY | TCTTCKQPFT | SAWFLLQHAQ | NTHGLRIYLE | 
    250:
    SEHGSPLTPR | VGIPSGLGAE | CPSQPPLHGI | HIADNNPFNL | LRIPGSVSRE | 
    300:
    ASGLAEGRFP | PTPPLFSPPP | RHHLDPHRIE | RLGAEEMALA | THHPSAFDRV | 
    350:
    LRLNPMAMEP | PAMDFSRRLR | ELAGNTSSPP | LSPGRPSPMQ | RLLQPFQPGS | 
    400:
    KPPFLATPPL | PPLQSAPPPS | QPPVKSKSCE | FCGKTFKFQS | NLVVHRRSHT | 
    450:
    GEKPYKCNLC | DHACTQASKL | KRHMKTHMHK | SSPMTVKSDD | GLSTASSPEP | 
    500:
    GTSDLVGSAS | SALKSVVAKF | KSENDPNLIP | ENGDEEEEED | DEEEEEEEEE | 
    550:
    EEEELTESER | VDYGFGLSLE | AARHHENSSR | GAVVGVGDES | RALPDVMQGM | 
    600:
    VLSSMQHFSE | AFHQVLGEKH | KRGHLAEAEG | HRDTCDEDSV | AGESDRIDDG | 
    650:
    TVNGRGCSPG | ESASGGLSKK | LLLGSPSSLS | PFSKRIKLEK | EFDLPPAAMP | 
    700:
    NTENVYSQWL | AGYAASRQLK | DPFLSFGDSR | QSPFASSSEH | SSENGSLRFS | 
    750:
    TPPGELDGGI | SGRSGTGSGG | STPHISGPGP | GRPSSKEGRR | SDTCEYCGKV | 
    800:
    FKNCSNLTVH | RRSHTGERPY | KCELCNYACA | QSSKLTRHMK | THGQVGKDVY | 
    835:
    KCEICKMPFS | VYSTLEKHMK | KWHSDRVLNN | DIKTE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    String:
    SMR:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human BCL-11A
    Cat.:
    E14965h
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    Packing:
    96T
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    ELISA Kit for Human BCL-11A
    Cat.:
    E14965m
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    Packing:
    96T
    CLIA Kit for Human BCL-11A
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    U14965h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human BCL-11A
    Cat.:
    U14965m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human BCL-11A
    Cat.:
    P14965Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human BCL-11A
    Cat.:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human BCL-11A
    Monoclonal Antibody for Human BCL-11A
    Protein for Human BCL-11A
    Protein for Human BCL-11A

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human EVI9, a homologue of the mouse myeloid leukemia gene, is expressed in the hematopoietic progenitors and down-regulated during myeloid differentiation of HL60 cells."
      Saiki Y. , Yamazaki Y. , Yoshida M. , Katoh O. , Nakamura T.
      Genomics70:387-391(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 4 AND 5);SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Fetal brain.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3);TISSUE SPECIFICITY
    3. 3.
      "Identification of a new isoform for B-cell CLL/lymphoma 11A (BCL11A) gene."
      Suriyapperuma S.P. , Sarfarazi M.
      Submitted (2003-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6)
    4. 4.
      "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Nakayama M. , Nakajima D. , Kikuno R. , Ohara O.
      DNA Res.8:85-95(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Lymph.
    7. 7.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 636-835
      tissue: Embryo.
    8. 8.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-205 AND SER-608;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-332; SER-625; SER-630 AND THR-701;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] PHE-142
    12. 12.
      "A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15."
      Menzel S. , Garner C. , Gut I. , Matsuda F. , Yamaguchi M. , Heath S. , Foglio M. , Zelenika D. , Boland A. , Rooks H. , Best S. , Spector T.D. , Farrall M. , Lathrop M. , Thein S.L.
      Nat. Genet.39:1197-1199(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POLYMORPHISM;ASSOCIATION WITH FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 5
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