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Index > Protein center > Bcl11b(Gene name) > Mouse
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  • Bcl11b (Gene name),
  • B-cell lymphoma/leukemia 11B (Protein name ),  BC11B_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Bcl11b(Ctip2;Rit1);
    Protein name:
    B-cell lymphoma/leukemia 11B(BCL-11B);
    Alternative:
    COUP-TF-interacting protein 2;B-cell CLL/lymphoma 11B;Radiation-induced tumor suppressor gene 1 protein(mRit1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with TFCOUP1, SIRT1, ARP1 and EAR2.
    Function:
    Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    884
    Sequence:
    50:
    MSRRKQGNPQ | HLSQRELITP | EADHVEATIL | EEDEGLEIEE | PSSLGLMVGG | 
    100:
    PDPDLLTCGQ | CQMNFPLGDI | LVFIEHKKKQ | CGGLGPCYDK | VLDKSSPPPS | 
    150:
    SRSELRRVSE | PVEIGIQVTP | DEDDHLLSPT | KGICPKQENI | AGPCRPAQLP | 
    200:
    SMAPIAASSS | HPPTSVITSP | LRALGVLPPC | FPLPCCGARP | ISGDGTQGEG | 
    250:
    QMEAPFGCQC | ELSGKDEPSS | YICTTCKQPF | NSAWFLLQHA | QNTHGFRIYL | 
    300:
    EPGPASTSLT | PRLTIPPPLG | PETVAQSPLM | NFLGDSNPFN | LLRMTGPILR | 
    350:
    DHPGFGEGRL | PGTPPLFSPP | PRHHLDPHRL | SAEEMGLVAQ | HPSAFDRVMR | 
    400:
    LNPMAIDSPA | MDFSRRLREL | AGNSSTPPPV | SPGRGNPMHR | LLNPFQPSPK | 
    450:
    SPFLSTPPLP | PMPAGTPPPQ | PPAKSKSCEF | CGKTFKFQSN | LIVHRRSHTG | 
    500:
    EKPYKCQLCD | HACSQASKLK | RHMKTHMHKA | GSLAGRSDDG | LSAASSPEPG | 
    550:
    TSELPGDLKA | ADGDFRHHES | DPSLGPEPED | DEDEEEEEEE | LLLENESRPE | 
    600:
    SSFSMDSELG | RGRENGGGVP | PGVAGAGAAA | AALADEKALA | LGKVMEDAGL | 
    650:
    GALPQYGEKR | GAFLKRAGDT | GDAGAVGCGD | AGAPGAVNGR | GGAFAPGAEP | 
    700:
    FPALFPRKPA | PLPSPGLGGP | ALHAAKRIKV | EKDLELPPAA | LIPSENVYSQ | 
    750:
    WLVGYAASRH | FMKDPFLGFT | DARQSPFATS | SEHSSENGSL | RFSTPPGDLL | 
    800:
    DGGLSGRSGT | ASGGSTPHLG | GPGPGRPSSK | EGRRSDTCEY | CGKVFKNCSN | 
    850:
    LTVHRRSHTG | ERPYKCELCN | YACAQSSKLT | RHMKTHGQIG | KEVYRCDICQ | 
    884:
    MPFSVYSTLE | KHMKKWHGEH | LLTNDVKIEQ | AERS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse BCL-11B
    Cat.:
    E14966h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse BCL-11B
    Cat.:
    E14966m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse BCL-11B
    Cat.:
    U14966m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse BCL-11B
    Cat.:
    U14966h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse BCL-11B
    Polyclonal Antibody for Mouse BCL-11B
    Monoclonal Antibody for Mouse BCL-11B
    Monoclonal Antibody for Mouse BCL-11B
    Protein for Mouse BCL-11B
    Protein for Mouse BCL-11B

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Homozygous deletions and point mutations of the Rit1/Bcl11b gene in gamma-ray induced mouse thymic lymphomas."
      Wakabayashi Y. , Inoue J. , Takahashi Y. , Matsuki A. , Kosugi-Okano H. , Shinbo T. , Mishima Y. , Niwa O. , Kominami R.
      Biochem. Biophys. Res. Commun.301:598-603(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3);VARIANTS THR-676; CYS-783 AND SER-849
    2. 2.
      "Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors."
      Avram D. , Fields A. , Pretty On Top K. , Nevrivy D.J. , Ishmael J.E. , Leid M.
      J. Biol. Chem.275:10315-10322(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);INTERACTION WITH TFCOUP1; EAR2 AND ARP1
      strain: BALB/c.
      tissue: Brain.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 331-884
      strain: NOD.
      tissue: Thymus.
    5. 5.
      "Bcl11b is required for differentiation and survival of alphabeta T lymphocytes."
      Wakabayashi Y. , Watanabe H. , Inoue J. , Takeda N. , Sakata J. , Mishima Y. , Hitomi J. , Yamamoto T. , Utsuyama M. , Niwa O. , Aizawa S. , Kominami R.
      Nat. Immunol.4:533-539(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    6. 6.
      "Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression."
      Senawong T. , Peterson V.J. , Avram D. , Shepherd D.M. , Frye R.A. , Minucci S. , Leid M.
      J. Biol. Chem.278:43041-43050(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SIRT1
    7. 7.
      "In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice."
      Tirard M. , Hsiao H.H. , Nikolov M. , Urlaub H. , Melchior F. , Brose N.
      Proc. Natl. Acad. Sci. U.S.A.109:21122-21127(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION WITH SUMO1
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