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Index > Protein center > BCL2(Gene name) > Chicken
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  • BCL2 (Gene name),
  • Apoptosis regulator Bcl-2 (Protein name ),  BCL2_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    BCL2(BCL-2);
    Protein name:
    Apoptosis regulator Bcl-2;
    Alternative:

    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Forms homodimers, and heterodimers with BAX, BAD, BAK and Bcl-X(L). Heterodimerization with BAX requires intact BH1 and BH2 motifs, and is necessary for anti-apoptotic activity (By similarity). Also interacts with APAF1 and RAF-1.
    Function:
    Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
    Subcellular Location:
    Mitochondrion outer membrane Single-pass membrane protein Nucleus membrane Single-pass membrane protein Endoplasmic reticulum membrane Single-pass membrane protein
    Protein Attributes:
    Sequence length:
    233
    Sequence:
    50:
    MAHPGRRGYD | NREIVLKYIH | YKLSQRGYDW | AAGEDRPPVP | PAPAPAAAPA | 
    100:
    AVAAAGASSH | HRPEPPGSAA | ASEVPPAEGL | RPAPPGVHLA | LRQAGDEFSR | 
    150:
    RYQRDFAQMS | GQLHLTPFTA | HGRFVAVVEE | LFRDGVNWGR | IVAFFEFGGV | 
    200:
    MCVESVNREM | SPLVDNIATW | MTEYLNRHLH | NWIQDNGGWD | AFVELYGNSM | 
    233:
    RPLFDFSWIS | LKTILSLVLV | GACITLGAYL | GHK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    E0778r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    E0778b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    E0778h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    E0778m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    E0778c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    E0778d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    U0778r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    U0778b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    U0778h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    U0778d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    U0778m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Apoptosis regulator Bcl-2
    Cat.:
    U0778c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Cat.:
    P0778Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Polyclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Cat.:
    P0778Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Cat.:
    P0778Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Polyclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Monoclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Monoclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Monoclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Monoclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Monoclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Monoclonal Antibody for Chicken Apoptosis regulator Bcl-2
    Protein for Chicken Apoptosis regulator Bcl-2
    Protein for Chicken Apoptosis regulator Bcl-2
    Protein for Chicken Apoptosis regulator Bcl-2
    Protein for Chicken Apoptosis regulator Bcl-2
    Protein for Chicken Apoptosis regulator Bcl-2
    Protein for Chicken Apoptosis regulator Bcl-2

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    References
    1. 1.
      "Isolation and characterization of the chicken bcl-2 gene: expression in a variety of tissues including lymphoid and neuronal organs in adult and embryo."
      Eguchi Y. , Ewert D.L. , Tsujimoto Y.
      Nucleic Acids Res.20:4187-4192(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Molecular cloning and DNA sequence analysis of cDNA encoding chicken homologue of the Bcl-2 oncoprotein."
      Cazals-Hatem D.L. , Louie D.C. , Tanaka S. , Reed J.C.
      Biochim. Biophys. Acta1132:109-113(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: B-cell lymphoma.
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